A survey-based, quasi-experimental study assessing a high-cannabidiol suppository for menstrual-related pain and discomfort DOI Creative Commons
Mary Kathryn Dahlgren, Rosemary T. Smith, Deniz Kosereisoglu

et al.

npj Women s Health, Journal Year: 2024, Volume and Issue: 2(1)

Published: Aug. 29, 2024

Abstract The endocannabinoid system is involved in gynecological functions, with cannabidiol (CBD) demonstrating promise for alleviating menstrual-related symptoms. This survey-based, quasi-experimental study assessed pro re nata (PRN) use of a commercially-available, hemp-derived, broad-spectrum, high-CBD (100 mg) vaginal suppository (Foria®) pain and discomfort compared to treatment-as-usual (TAU) group (CBD n = 77, TAU 230), survey assessments collected at baseline two monthly follow-ups (~2 menstrual cycles). CBD demonstrated significantly reduced frequency severity symptoms, impact symptoms on daily functioning, need analgesics, number analgesics used relative the ( ps ≤ 0.032). Correlation analyses indicated potential dose-dependent response, increased associated greater reduction 0.025). Most participants reported least moderate improvement (follow-up 1 72.9%, follow-up 2 81.1%). Future studies (including replication randomized clinical trials) assessing pharmacokinetics/pharmacodynamics, mechanism(s) action, efficacy other indications, adverse events (e.g., drug-drug interactions) are indicated.

Language: Английский

Cannabis use across the menstrual cycle: The impact of negative affect and cannabis use motives DOI
Paige E. Morris, Paul L. Soto, Julia D. Buckner

et al.

Addictive Behaviors, Journal Year: 2025, Volume and Issue: 164, P. 108284 - 108284

Published: Feb. 4, 2025

Language: Английский

Citations

0
Exploring hidden risks and empowerment in women’s acquisition of medicinal cannabis from illegal markets: a qualitative study DOI Creative Commons
Vinuli Withanarachchie, Marta Rychert, Chris Wilkins

et al.

Drugs Education Prevention and Policy, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 13

Published: March 21, 2025

Language: Английский

Citations

0
Treatment Strategies for Painful Pelvic Floor Conditions: A Focus on the Potential Benefits of Cannabidiol DOI Creative Commons
Roberto Bonanni, Patrizia Ratano, Ida Cariati

et al.

Biomolecules, Journal Year: 2024, Volume and Issue: 14(12), P. 1627 - 1627

Published: Dec. 19, 2024

Painful conditions of the pelvic floor include a set disorders region, discreetly prevalent in female population, which pain emerges as predominant symptom. Such have significant impact on quality life they impair couple relationships and promote states anxiety irascibility affected individuals. Although numerous treatment approaches been proposed for management such disorders, there is need to identify strategies muscle relaxation, counter pain, reduce inflammation. The endocannabinoid system (ECS) represents complex spread throughout body involved regulation physiological processes representing potential therapeutic target mood well management. Cannabidiol (CBD), acting ECS, can relief from hyperalgesia allodynia typical affecting relaxation by restoring balance this delicate anatomical region. However, its use currently limited due lack evidence supporting efficacy harmlessness, mechanism action ECS remains partially unexplored day. This comprehensive review literature examines major brings together main CBD disorders.

Language: Английский

Citations

1
Cannabis sativa L. roots from Northeast Brazil reduce abdominal contortions in a mouse model of primary dysmenorrhea DOI
Tarcísio Cícero de Lima Araújo, Pedro Modesto Nascimento Menezes,

Tiago Feitosa Ribeiro

et al.

Journal of Ethnopharmacology, Journal Year: 2023, Volume and Issue: 318, P. 116891 - 116891

Published: July 8, 2023

Language: Английский

Citations

1
Prevalence of Dysmenorrhea and its Management among Undergraduate Students of the University of Port Harcourt, Nigeria DOI Open Access

Faustina Chiamaka Irozulike,

Nicholas Asiwe,

Joy Wilberforce Ekokodje

et al.

Asian Journal of Advanced Research and Reports, Journal Year: 2023, Volume and Issue: 17(12), P. 19 - 28

Published: Nov. 6, 2023

Background: Dysmenorrhea is a pain felt by women before or during menstruation and accompanied some symptoms like headache, dizziness, food cravings, mood swings, fatigue. Many ways have been adopted for the management of dysmenorrhea. The study aims to evaluate prevalence dysmenorrhea its among university students. Methods: A total two hundred (200) female students were involved in this study. cross-sectional descriptive design was used where sampled randomly questionnaire collect data obtained analyzed using IBM SPSS version 26. Results: found that majority population experiences (81.5%) respondents experienced menstrual flow within 4-5 days with 37% experiencing severe pain. Symptoms include anxiety, tender breasts, fatigue, irritating mood, depression, vomiting, diarrhea, headache. Management varies, 23.5% synthetic drugs 1.5% local herbal practices. Conclusion: There high University presenting most local/herbal medication.

Language: Английский

Citations

1
Medical Cannabis Prescription Practices and Quality of Life in Thai Patients: A Nationwide Prospective Observational Cohort Study DOI Creative Commons

Pramote Stienrut,

Krit Pongpirul, Phanupong Phutrakool

et al.

Medical Cannabis and Cannabinoids, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 1

Published: July 17, 2024

The legalization of cannabis in Thailand has renewed interest its traditional medical use. This study aimed to explore the prescribing patterns practitioners and assess impact oil on patients' quality life, with a specific focus comparing outcomes between cancer non-cancer patients.

Language: Английский

Citations

0
A survey-based, quasi-experimental study assessing a high-cannabidiol suppository for menstrual-related pain and discomfort DOI Creative Commons
Mary Kathryn Dahlgren, Rosemary T. Smith, Deniz Kosereisoglu

et al.

npj Women s Health, Journal Year: 2024, Volume and Issue: 2(1)

Published: Aug. 29, 2024

Abstract The endocannabinoid system is involved in gynecological functions, with cannabidiol (CBD) demonstrating promise for alleviating menstrual-related symptoms. This survey-based, quasi-experimental study assessed pro re nata (PRN) use of a commercially-available, hemp-derived, broad-spectrum, high-CBD (100 mg) vaginal suppository (Foria®) pain and discomfort compared to treatment-as-usual (TAU) group (CBD n = 77, TAU 230), survey assessments collected at baseline two monthly follow-ups (~2 menstrual cycles). CBD demonstrated significantly reduced frequency severity symptoms, impact symptoms on daily functioning, need analgesics, number analgesics used relative the ( ps ≤ 0.032). Correlation analyses indicated potential dose-dependent response, increased associated greater reduction 0.025). Most participants reported least moderate improvement (follow-up 1 72.9%, follow-up 2 81.1%). Future studies (including replication randomized clinical trials) assessing pharmacokinetics/pharmacodynamics, mechanism(s) action, efficacy other indications, adverse events (e.g., drug-drug interactions) are indicated.

Language: Английский

Citations

0