Clemastine improves emotional and social deficits in adolescent social isolation mice by reversing demyelination DOI
Dan Guo,

Yuan Yao,

Xiumin Liu

et al.

Pharmacology Biochemistry and Behavior, Journal Year: 2024, Volume and Issue: 242, P. 173824 - 173824

Published: Sept. 1, 2024

Language: Английский

Bibliometric analysis of the intestinal microbiota and demyelinating diseases, particularly multiple sclerosis, since 2014 DOI Creative Commons
Ling Chen,

Lijun Wu,

Changyin Yu

et al.

Frontiers in Neuroscience, Journal Year: 2025, Volume and Issue: 19

Published: March 5, 2025

The gut-brain axis (GBA) represents a complex, bidirectional communication network that connects the central nervous system (CNS) and gastrointestinal system. Our study aimed to explore correlation between intestinal microbiota demyelinating diseases from bibliometric perspective, focusing on research since 2014. A comprehensive search was carried out Web of Science Core Collection (WoSCC) locate studies diseases, with focus publications 1 January 2014 29 March 2024. We visualized analyzed data using VOSviewer, CiteSpace, Charticulator. gathered 429 scholarly articles disorders published in past 10 years. Research concerning has demonstrated consistent increase frequency over time. USA highest number publications, while Canada average citations, reaching as high 3,429, which is greater than USA. Moreover, journal Frontiers Immunology, 33 1,494 citations. majority scholars focused "multiple sclerosis" "gut microbiota," are primary keywords field diseases. This conducted analysis existing investigating Using advanced tools such VOSviewer this intricate relationship pathogenesis conditions. In addition, used literature statistical identify hotspots future directions field.

Language: Английский

Citations

0

Astragaloside II, a natural saponin, facilitates remyelination in demyelination neurological diseases via p75NTR receptor mediated β-catenin/Id2/MBP signaling axis in oligodendrocyte precursor cells DOI Creative Commons

Jinfeng Yuan,

Yanlin Tao, Mengxue Wang

et al.

Journal of Advanced Research, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0

Demyelinating Diseases: From Molecular Mechanisms to Therapeutic Strategies DOI Open Access
Antonietta Bernardo, Sergio Visentin

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(5), P. 4596 - 4596

Published: Feb. 27, 2023

Demyelinating diseases are a group of pathologies characterized by the alteration myelin-that is, coating that wraps around most nerve fibres central and peripheral nervous system, whose goal is improvement conduction preservation energy spent during action potential propagation [...].

Language: Английский

Citations

5

The potential of noninvasive brain stimulation techniques for the treatment of central nervous system demyelinating diseases: a narrative review DOI
Yinan Shen, Zhenguo Lin, Wen Liu

et al.

Advanced technology in neuroscience ., Journal Year: 2024, Volume and Issue: 1(2), P. 211 - 228

Published: Nov. 27, 2024

Noninvasive brain stimulation techniques have emerged as a promising therapeutic option for various central nervous system demyelinating diseases. Demyelinating diseases represent group of pathological conditions that impact the or peripheral system. They are characterized by damage to loss myelin sheath surrounding nerve fibers. This sheaths disrupts signal transmission, leading wide range signs and symptoms associated with neurological impairment. Treatment usually aligns specific underlying cause. can affect neuronal electrical activity glial cell function, suggesting potential intervention. In this narrative review, we explore noninvasive treatment disorders. techniques, including transcranial magnetic stimulation, focused ultrasound optogenetic low-intensity pulsed ultrasound, photobiomodulation, been shown potentially intervene in affecting cells function. addition, review summarizes applications mechanisms how these promote regeneration improve disease prognosis. also research advances multiple sclerosis, acute disseminated encephalomyelitis, progressive multifocal leukoencephalopathy, neuromyelitis optical spectrum disorder. promoting oligodendrocyte proliferation differentiation, enhancing regeneration, modulating immune responses. Although disorders, their use treating remains challenging. For example, is relatively new technique advantages high spatial resolution ability stimulate deep structures, but its safety efficacy clinical need be further investigated. Optogenetic offers highly precise neuromodulation, feasibility practice limited technical ethical constraints. Overall, significant diseases, needed optimize parameters, efficacy, gain insight into mechanism action. With continuous development technology in-depth trials, expected become an effective provide options such patients.

Language: Английский

Citations

1

Clemastine improves emotional and social deficits in adolescent social isolation mice by reversing demyelination DOI
Dan Guo,

Yuan Yao,

Xiumin Liu

et al.

Pharmacology Biochemistry and Behavior, Journal Year: 2024, Volume and Issue: 242, P. 173824 - 173824

Published: Sept. 1, 2024

Language: Английский

Citations

0