Gut Aging: A wane from the normal to repercussion and Gerotherapeutic strategies

Heliyon, Journal Year: 2024, Volume and Issue: 10(19), P. e37883 - e37883

Published: Sept. 13, 2024

Globally, age-related diseases represent a significant public health concern among the elderly population. In aging, healthy organs and tissues undergo structural functional changes that put aged adults at risk of diseases. Some include cancer, atherosclerosis, brain disorders, muscle atrophy (sarcopenia), gastrointestinal (GIT) etc. organs, decline in stem cell function is starting point many conditions extremely important GIT disorder development. Many studies have established aging affects cells their surrounding supportive niche components. Although there advancement treating intestinal rising population coupled with higher occurrence chronic gut ailments necessitates more effective therapeutic approaches to preserve health. Notable strategies such as Western medicine, traditional Chinese other health-promotion interventions been reported several hold promise mitigating disorders. This review highlights findings across various facets focus on aging-associated components, thus deviation from normal repercussion, well essential mitigate aging.

Language: Английский

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Inulin alleviates inflammatory response and gut barrier dysfunction via modulating microbiota in lipopolysaccharide-challenged broilers

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 282, P. 137208 - 137208

Published: Nov. 1, 2024

Language: Английский

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Revisiting dietary proanthocyanidins on blood glucose homeostasis from a multi-scale structural perspective

Current Research in Food Science, Journal Year: 2024, Volume and Issue: 9, P. 100926 - 100926

Published: Jan. 1, 2024

Multi-dimensional studies have consistently indicated the benefits of dietary proanthocyanidins on blood glucose homeostasis through consumption them from fruits, cereals and nuts. Proanthocyanidins various sources possess different structures, but even minor variations in structures influence their regulation glucose, including degree polymerization, galloacylation at C3, number hydroxyl groups B ring linkage type. Therefore, this Review details role three types (procyanidins, prodelphinidins propelargonidins) control underlying mechanisms, structural features contribute to. Due to extremely low bioavailability, mainly ameliorate high by luminal effects: inhibit enzyme activities, improve structure gut microbiota, protect intestinal barrier function. A few absorbed exert insulin-like effects targeted organs. Prodelphinidin gallates exhibit greater hypoglycemic activities than others, due C3 amounts ring. Because action pathways, comprehensive consideration type density was required. Further understanding these relationships can concrete diet therapeutic opportunities for proanthocyanidins.

Language: Английский

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Mechanism of procyanidins for health functionality by improving the intestinal environment

Bioscience Biotechnology and Biochemistry, Journal Year: 2023, Volume and Issue: 88(4), P. 345 - 351

Published: Dec. 6, 2023

Procyanidins are one of the polyphenols consisting multiple flavan-3-ols (eg epicatechin). They have a complex chemical structure, with degree polymerization and linked position varying among various foods, such as apples chocolate. Physiological functional studies procyanidins investigated their mechanisms in cells animals based on antioxidant effects. Recently, intestinal environment, including microflora, has played an important role energy metabolism health status host. Regulation environment by dietary is becoming new concept functions, we begun to investigate mechanism apple procyanidins, focusing gut microbiota metabolites our research. In this minireview, will discuss effects procyanidin ingestion metabolites.

Language: Английский

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Abordaje nutricional en el síndrome metabólico: Un estudio de revisión

Ciencia Latina Revista Científica Multidisciplinar, Journal Year: 2023, Volume and Issue: 7(2), P. 7130 - 7161

Published: May 12, 2023

El síndrome metabólico, es un trastorno que promueve el desarrollo de estados inflamatorios bajo grado, debido al incremento tejido adiposo. Siendo constituido como problema global, compromete estado salud, ya que, conduce surgimiento patologías metabólicas la Obesidad, Diabetes Mellitus Tipo II (DM2), Hiperlipidemia e HTA. Por ello, propósito este estudio fue elaborar una revisión bibliográfica referente a los patrones y estrategias dietoterapéuticas actividad física, regulen factores riesgo asociados metabólico. Se realizaron búsquedas en PubMed, Multidisciplinary Digital Publishing Institute (MDPI), Dialnet Google Scholar, desde 15 noviembre del 2022 25 febrero 2023. En cual, se incluyó, 35 artículos, publicados entre año 2018 A partir cuales, logró describir Síndrome Metabólico, además tipos dietas, alimentos nutraceúticos ciertos micronutrientes (Vitamina C, D magnesio) empleados para tratamiento prevención concluyó pesar no existir modelo nutricional o física establecido manejo esta patología uso combinado aeróbica anaeróbica, más patrón dietético caracterizan dieta mediterránea, redujo valores antropométricos (IMC, peso circunferencia cintura) bioquímicos, mediante descenso CT, LDL-C, triglicéridos mejor control tensión arterial sensibilidad insulina. Reduciendo cardiometabólico mortalidad precoz individuos metabólicamente descompensados.

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Gut Aging: A Wane from the Normal to Repercussion and Gerotherapeutic Strategies

Published: Jan. 1, 2024

Language: Английский

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Libro de Autoría colectiva “Estudios Centrados en Ciencias de la Salud” Vol 1 Núm 4

CID - Centro de Investigación y Desarrollo eBooks, Journal Year: 2023, Volume and Issue: unknown

Published: Jan. 1, 2023

Libro de Autoría colectiva “Estudios Centrados en Ciencias la Salud” Vol 1 Núm 4

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