The generation and transformation mechanisms of reactive oxygen species in the environment and their implications for pollution control processes: a review.

Environmental Research, Journal Year: 2024, Volume and Issue: 260, P. 119592 - 119592

Published: July 14, 2024

Language: Английский

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Hydrolysis, Ligand Exchange, and Redox Properties of Vanadium Compounds: Implications of Solution Transformation on Biological, Therapeutic, and Environmental Applications

Chemical Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 16, 2025

Vanadium is a transition metal with important industrial, technological, biological, and biomedical applications widespread in the environment living beings. The different reactions that vanadium compounds (VCs) undergo presence of proteins, nucleic acids, lipids metabolites under mild physiological conditions are reviewed. In present naturally or through anthropogenic sources, latter having an environmental impact caused by dispersion VCs atmosphere aquifers. has versatile chemistry interconvertible oxidation states, variable coordination number geometry, ability to form polyoxidovanadates various nuclearity structures. If VC added water-containing it can hydrolysis, ligand-exchange, redox, other types changes, determined speciation vanadium. Importantly, solution likely differ from introduced into system varies concentration. Here, hydrolytic ligand-exchange chemical reactions, influence pH, concentration, salt, specific solutes, biomolecules, on described. One our goals this work highlight need for assessment speciation, so beneficial toxic species might be identified mechanisms action elucidated.

Language: Английский

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The future of polyoxymetalates for biological and chemical apllications

Coordination Chemistry Reviews, Journal Year: 2023, Volume and Issue: 493, P. 215306 - 215306

Published: June 20, 2023

Language: Английский

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Anticancer perspectives of vanadium complexes

Inorganic Chemistry Communications, Journal Year: 2024, Volume and Issue: 161, P. 112014 - 112014

Published: Jan. 5, 2024

Language: Английский

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Calcium (Ca2+) signaling in plants: A plant stress perspective

South African Journal of Botany, Journal Year: 2024, Volume and Issue: 169, P. 464 - 485

Published: May 4, 2024

Language: Английский

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2-Aminofluorene-Based Imine Compounds: Single Crystal Structure, Vanadium(III) detection and Anticancer Activity

Journal of Molecular Structure, Journal Year: 2025, Volume and Issue: unknown, P. 141810 - 141810

Published: Feb. 1, 2025

Language: Английский

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Co-application of potassium and thiourea for mitigating salinity stress in wheat seedlings

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: April 26, 2025

Salt stress disrupts ionic homeostasis and induces oxidative damage, leading to reduced plant growth development. Determining the lethal dose of NaCl is essential for developing effective mitigation strategies. Potassium other antioxidant regulatory compounds often prove insufficient in addressing salt-induced toxicity, especially wheat. This laboratory experiment aimed determine concentration that reduces by 50% evaluate effectiveness different approaches involving potassium thiourea supplementation at 0 mM, 10 15 mM under identified condition. The followed a factorial arrangement with three biological replications. Results showed 198 decreased germination 50%. combined application significantly improved homeostasis, 14% increase overall ion balance. was achieved reducing sodium ions 28.55% increasing 23.92%. Furthermore, interactive enhances various parameters, including shoot root length (by 14.20-32.82%), shoot/root fresh dry weight 18.56/8.89% 26.60/25.52%, respectively). These improvements were attributed enhanced physiological processes, 10.23% net photosynthetic rate, 30.20% stomatal conductance, 6.70% transpiration an 8.12% internal carbon dioxide concentrations 10.13% improvement relative water content. Additionally, markers, such as hydrogen peroxide malonaldeahyde, 8.43% 26.20%, respectively. reduction associated increased enzyme activity, 13.69% superoxide dismutase, 8.91% catalase, 20.18% peroxidase, 13.11% ascorbate peroxidase. decrease contributed 8.48% membrane stability 17.06% enhancement Principle component analysis confirmed efficacy K15 + TU15 treatment improving wheat salt tolerance. simultaneous K TU effectively mitigated toxicity enhancing through activity

Language: Английский

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Vanadium Compounds with Antidiabetic Potential

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(21), P. 15675 - 15675

Published: Oct. 27, 2023

Over the last four decades, vanadium compounds have been extensively studied as potential antidiabetic drugs. With present review, we aim at presenting a general overview of most promising and main results obtained with in vivo studies, reported from 1899-2023. The chemistry is explored, discussing importance structure biochemistry vanadate impact its similarity phosphate on effect. spectroscopic characterization discussed, particularly magnetic resonance methodologies, emphasizing relevance for understanding species activity, speciation, interaction biological membranes. Finally, relevant studies regarding use to treat diabetes are summarized, considering both animal models human clinical trials. An hypotheses explaining activity these presented, accepted pathway involving phosphatase kinase enzymes involved insulin signaling cascade. From our point view, major discoveries pharmacological action this family not yet fully understood. Thus, still believe that presents help metabolic control management diabetes, either an insulin-like drug or adjuvant. We look forward next forty years research field, aiming discover compound desired therapeutic properties.

Language: Английский

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Repurposing Therapeutic Drugs Complexed to Vanadium in Cancer

Pharmaceuticals, Journal Year: 2023, Volume and Issue: 17(1), P. 12 - 12

Published: Dec. 21, 2023

Repurposing drugs by uncovering new indications for approved accelerates the process of establishing treatments and reduces high costs drug discovery development. Metal complexes with clinically allow further opportunities in cancer therapy—many vanadium compounds have previously shown antitumor effects, which makes a suitable metal to complex therapeutic drugs, potentially improving their efficacy treatment. In this review, covering last 25 years research field, we identified non-oncology-approved as ligands obtain different complexes. Metformin-decavanadate, vanadium-bisphosphonates, vanadyl(IV) non-steroidal anti-inflammatory cetirizine imidazole-based oxidovanadium(IV) complexes, each has parent known medicinal properties indications, all showed potential novel anticancer treatments. Nevertheless, precise mechanisms action these against are still not fully understood.

Language: Английский

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Green route synthesis of transition metal doped V2O5 nanoparticles, with emerging biomedical applications

Results in Chemistry, Journal Year: 2024, Volume and Issue: 7, P. 101373 - 101373

Published: Jan. 1, 2024

In this proposed work we synthesized the pristine V2O5 nanoparticles and Ag (3.2 %, 14.5 23.4 %), Cd (5.8 23.5 35.7 %) Ru doped (4.9 20.7 32 using vigna radiata extract. The were characterized by various techniques like UV-DRS, FT-IR, XRD, FE-SEM HR-TEM. antibacterial activities of studied bacterial strains such as Staphylococcus aures (S.aureus), Streptococcus pneumoniea (S. pneumoniea), Pseudomonas aeruginosae (P. aeruginosae), Klebsiella (K. pneumoniea) Escherichia coli (E.coli). Among potential bacterium growth inhibition 99 % for S.aureus was observed CV-5. binding efficiency with biomolecule BSA UV–visible absorption emission spectral techniques. It found that there is a interaction between them constant values are in range from 104 to 105 M−1. quenching rate (kq) value bigger than maximum diffusion biomolecules 2.0 x 1010M−1s−1 suggesting static type. glucose oxidation studies lower high current density 440 mA/cm2 occurred NPs.

Language: Английский

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