Neuroprotective Effect of Curcumin–Metavanadate in the Hippocampus of Aged Rats DOI Open Access

Sonia Irais González‐Cano,

Ulises Peña‐Rosas,

Guadalupe Muñoz‐Arenas

et al.

Synapse, Journal Year: 2025, Volume and Issue: 79(1)

Published: Jan. 1, 2025

ABSTRACT Brain aging is a multifactorial process that includes reduction in the biological and metabolic activity of individuals. Oxidative stress inflammatory processes are characteristic brain aging. Given current problems, need arises to implement new therapeutic approaches. Polyoxidovanadates (POV), as well curcumin, have stood out for their participation variety activities. This work aimed evaluate coupling metavanadate curcumin (Cuma‐MV) on learning, memory, redox balance, neuroinflammation, cell death hippocampal region (CA1 CA3) dentate gyrus (DG) aged rats. Rats 18 months old were administered daily dose (Cuma), sodium (MV), or Cuma‐MV two months. The results demonstrated administration 60 days rats improved short‐ long‐term recognition decreased reactive oxygen species, substantially lipoperoxidation hippocampus. Furthermore, superoxide dismutase catalase increased animals treated with Cuma‐MV. It important highlight treatment exhibited significantly greater effect than treatments MV Cuma all parameters evaluated. Finally, we conclude represents potential option prevention cognitive decline associated

Language: Английский

Maintaining quality of postharvest green pepper fruit using melatonin by regulating membrane lipid metabolism and enhancing antioxidant capacity DOI
Tianyu Huang, Xiaohong Kou,

LinXiang Qiao

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 460, P. 140671 - 140671

Published: July 27, 2024

Language: Английский

Citations

4
Sturgeon (Acipenser schrenckii) spinal cord peptides: Antioxidative and acetylcholinesterase inhibitory efficacy and mechanisms DOI

Zu Xiaoyan,

Qing Zhao, Wenbo Liu

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 461, P. 140834 - 140834

Published: Aug. 12, 2024

Language: Английский

Citations

4
“Copper-Loaded Microplastics Unleash Endoplasmic Reticulum Stress-driven Liver Apoptosis in Fish Channa punctatus” DOI Creative Commons

Jumman Bakhasha,

Vaishnavi Saxena,

Neeti Arya

et al.

Emerging contaminants, Journal Year: 2024, Volume and Issue: 11(1), P. 100422 - 100422

Published: Oct. 9, 2024

Language: Английский

Citations

4
Nanomaterial-enabled drug transport systems: a comprehensive exploration of current developments and future avenues in therapeutic delivery DOI

Shatabdi Basu,

Prabir Kumar Biswas,

Mariya Anto

et al.

3 Biotech, Journal Year: 2024, Volume and Issue: 14(12)

Published: Nov. 4, 2024

Language: Английский

Citations

4
Neuroprotective Effect of Curcumin–Metavanadate in the Hippocampus of Aged Rats DOI Open Access

Sonia Irais González‐Cano,

Ulises Peña‐Rosas,

Guadalupe Muñoz‐Arenas

et al.

Synapse, Journal Year: 2025, Volume and Issue: 79(1)

Published: Jan. 1, 2025

ABSTRACT Brain aging is a multifactorial process that includes reduction in the biological and metabolic activity of individuals. Oxidative stress inflammatory processes are characteristic brain aging. Given current problems, need arises to implement new therapeutic approaches. Polyoxidovanadates (POV), as well curcumin, have stood out for their participation variety activities. This work aimed evaluate coupling metavanadate curcumin (Cuma‐MV) on learning, memory, redox balance, neuroinflammation, cell death hippocampal region (CA1 CA3) dentate gyrus (DG) aged rats. Rats 18 months old were administered daily dose (Cuma), sodium (MV), or Cuma‐MV two months. The results demonstrated administration 60 days rats improved short‐ long‐term recognition decreased reactive oxygen species, substantially lipoperoxidation hippocampus. Furthermore, superoxide dismutase catalase increased animals treated with Cuma‐MV. It important highlight treatment exhibited significantly greater effect than treatments MV Cuma all parameters evaluated. Finally, we conclude represents potential option prevention cognitive decline associated

Language: Английский

Citations

0