Vaccines, Journal Year: 2024, Volume and Issue: 12(11), P. 1263 - 1263
Published: Nov. 8, 2024
The vast, untapped potential of the world's oceans is revealing groundbreaking advancements in human health and vaccination. Microalgae such as
Language: Английский
Antibiotics, Journal Year: 2024, Volume and Issue: 13(6), P. 487 - 487
Published: May 24, 2024
This review explores the potential of antimicrobial metabolites derived from Caucasian medicinal plants as alternatives to conventional antibiotics. With rise antibiotic resistance posing a global health threat, there is pressing need investigate alternative sources agents. have traditionally been used for their therapeutic properties, and recent research has highlighted compounds. Representatives 15 families plant extracts (24 species) explored efficacy against these pathogens. The effect on Gram-positive Gram-negative bacteria fungi discussed in this paper. By harnessing bioactive present plants, study aims contribute development new treatments that can effectively combat bacterial infections while minimizing risk emergence. Herein we discuss following classes compounds exhibiting activity: phenolic compounds, flavonoids, tannins, terpenes, saponins, alkaloids, sulfur-containing Allium species. discusses pharmacological properties selected extraction characterization metabolites, mechanisms action antibacterial antifungal applications clinical settings. Additionally, challenges future directions are addressed.
Language: Английский
Citations
13
Current Medicinal Chemistry, Journal Year: 2024, Volume and Issue: 31(28), P. 4407 - 4424
Published: Feb. 12, 2024
Abstract: The study of antioxidants is pivotal importance in biomedicine as these molecules could be involved biological pathways associated with disease. identification new together the acquisition a deeper knowledge on their biology, lead to use compounds drugs for innovative treatments. Plants are an important reservoir phytodrugs that many cases can isolated good extraction yields directly from vegetal source and often endowed low toxicity profile. Georgia, country situated Black Sea coast Caucasus region at intersection Western Asia Eastern Europe, renowned its unique woodland habitats immense diversity due great variety climate zones landscapes. Many wild plants area used remedies number illnesses local traditional medicine. However, scientific sources natural molecular components still far exhaustive. Therefore, present work we reviewed literature some main Georgian medicinal found several species valuable hydrophilic hydrophobic antioxidants, high ROS-scavenging ability. analysis also demonstrated most extracts beneficial suppressing multiple diseases vitro. This review will provide information scientists looking develop secure plant-based pharmaceuticals well rationale using treatment range diseases.
Language: Английский
Citations
10
Environmental Chemistry Letters, Journal Year: 2024, Volume and Issue: 22(4), P. 2133 - 2149
Published: April 27, 2024
Abstract The rising number of diseases and deaths caused by pollution modern lifestyle habits is a growing societal concern. Marine ecosystems are both victim to this human behaviour as recipient well being source medicinal chemicals which can cure variety diseases. In paper, we review the chemical basis water-based treatments their effects on health, while focusing threats marine potential benefits balneotherapy, thalassotherapy, bioactive species. We found that seawater has for skin demonstrating emollient properties, protection against barrier disruption, inhibition atopic dermatitis-like lesions. present putative mechanisms minerals, salts, organic matter slow down disease progression, through numerous activities, such anti-inflammatory, antioxidant, wound healing properties. Water-living organisms also have an impact producing biologically active compounds with beneficial health.
Language: Английский
Citations
6
Foods, Journal Year: 2024, Volume and Issue: 13(14), P. 2282 - 2282
Published: July 20, 2024
L. is commonly used in folk medicine the form of infusion or decoction to treat gastrointestinal diseases and flatulence as a carminative, antiseptic, anti-inflammatory agent. In this study, essential oil (EO) composition wild-grown
Language: Английский
Citations
3
Molecules, Journal Year: 2024, Volume and Issue: 29(13), P. 3075 - 3075
Published: June 27, 2024
The whole Hypericum patulum Thunb. plant is utilized in traditional medicine for its properties of clearing heat, detoxifying, soothing meridians, relaxing the liver, and stopping bleeding. In folk medicine, it frequently used to treat hepatitis, colds, tonsillitis, bruises. Phytochemical investigation a 30% ethanol extract fresh ripe fruits H. has resulted isolation two new pinane-type monoterpenoid glycosides 1–2, named patulumside E-F, three chain-shaped 3–5, G-H, J. Their structures were determined using extensive spectroscopic techniques, such as HR-ESI-MS, 1D 2D NMR spectroscopy, electronic circular dichroism (ECD) calculation. anti-inflammatory activities these compounds evaluated LPS-induced RAW264.7 cells. This research represents inaugural comprehensive phytochemical study patulum, paving way further exploration glycosides.
Language: Английский
Citations
1
Life, Journal Year: 2023, Volume and Issue: 13(11), P. 2127 - 2127
Published: Oct. 27, 2023
Asymmetry plays a major role in biology at all scales. This can be seen the helix of DNA, fact that human heart is on left side, or most people use their right hand. A single protein such as Myosin 1D induce helical motion another molecule. causes cells, organs, and even entire bodies to twist domino effect, causing left–right behaviour. More generally, athlete movements are often asymmetric and, during physical rehabilitation after injury, asymmetry visually discernible. Herein, we review molecular basis movement asymmetries report available knowledge few therapeutics investigated so far meloxicam. From more rehabilitative perspective, it very important effective methods control process resolving injury-related through complex specialised exercises, measurements, gait analysis, which provide useful information effectiveness plans. If for each athlete, normal range known, individually treated evolution monitored over time. Appropriate measures should taken if outside this range. In addition, genetic, physiological, psychological factors relevant health considered assessing improving exercise asymmetry, also discuss review. The main proposal work athletes treated, while taking into account athlete’s genetics, condition, previous injuries.
Language: Английский
Citations
1
Journal of Anatolian Environmental and Animal Sciences, Journal Year: 2024, Volume and Issue: 9(3), P. 430 - 436
Published: Aug. 21, 2024
The leaves and fruits of Laurus nobilis L. are used in pharmaceutical applications with their various activities such as antioxidant, antimicrobial anti-inflammatory. In current study, it was aimed to investigate antimicrobial, antiquorum sensing, cytotoxicity antiviral activity leaf fruit extract prepared by %70 ethanol. This study carried out the Department Medical Microbiology, Faculty Medicine, Karadeniz Technical University, Laurel collected from Trabozon province Black Sea region. Antimicrobial investigated agar well method. Gram negative, positive bacteria 2 fungi were used. Chromobacterium violaceum ATCC 12472 Pseudomonas aeruginosa PAO1 strains for antibiofilm anti swarming activities. cytotoxic effect ethanol plant on Vero, A549 MDA-MB-231 cell lines MTT extracts HSV-1 quorum sensing determined be moderate. It understood that showed antiproliferative effects a dose-dependent manner. needs more detail using different solvents.
Language: Английский
Citations
0
Vaccines, Journal Year: 2024, Volume and Issue: 12(11), P. 1263 - 1263
Published: Nov. 8, 2024
The vast, untapped potential of the world's oceans is revealing groundbreaking advancements in human health and vaccination. Microalgae such as
Language: Английский
Citations
0