Volatile Organic Compounds Detected in Amniotic Fluid of Women During Normal Pregnancy DOI Creative Commons
Régine Minet‐Quinard, Nicolas Gonçalves-Mendes, Denis Gallot

et al.

Exposure and Health, Journal Year: 2023, Volume and Issue: 16(5), P. 1155 - 1169

Published: Dec. 21, 2023

Abstract Exposure to volatile organic compounds (VOCs) during the fetal period may induce negative effects on children’s health (e.g. increased risk of low birth weight and imbalanced development). Whereas VOCs have been analysed extensively in various human biological fluids (i.e. urine, blood, breath), pregnancy only urine has studied no work performed amniotic fluid (AF), which is direct contact with fetus essential for its well-balanced development maturation. This study aimed detect AF investigate their links lifestyle habits pregnant women. The VOC composition collected from 76 healthy women was using a gas chromatograph coupled mass spectrometer. sources exposure were assessed questionnaire about home living conditions professional exposure. A total 126 belonging 13 chemical families detected AF. majority these (92) had an exogenous origin, presence linked habits, especially smoking fragrance use. Considering multiple organs, this important contribution literature exploring future potential relationships between abnormal development.

Language: Английский

Indoor Air Quality (IAQ) evaluation in a naturally ventilated church: key pollutants concentrations determined by incense burning practice over liturgical celebrations DOI
Alessia Di Gilio, Jolanda Palmisani, Lucio Pastore

et al.

Atmospheric Environment, Journal Year: 2025, Volume and Issue: unknown, P. 121143 - 121143

Published: March 1, 2025

Language: Английский

Citations

0
The Presence of Aromatic Substances in Incense: Determining Indoor Air Quality and Its Impact on Human Health DOI Creative Commons
Cristina Di Fiore, Pietro Pandolfi,

Fabiana Carriera

et al.

Applied Sciences, Journal Year: 2023, Volume and Issue: 13(12), P. 7344 - 7344

Published: June 20, 2023

Indoor air quality has become a topic of great concern. Burning incense recently been identified as one the primary sources volatile organic compounds, specifically benzene, in an indoor setting. The current paper aims to evaluate compound (VOC) emissions, particularly within environments through utilization experimental clean room. Experimental findings showed that 10 types sticks emitted benzene concentrations between 11.1 and 66.5 μg m−3, which were 2.5 lower than limit suggested for non-occupation exposure (160 m−3), by American Association Industrial Hygienists (ACGIH). Furthermore, correlation dimensions (diameter length) combustible parts stick was investigated indicated slight influence on release benzene. Taking into consideration substantial human health, coupled with lack precise legislation regarding residential settings, this research serves initial investigation noteworthy effects burning private public settings.

Language: Английский

Citations

8
Biomarkers of occupational benzene exposure: A Systematic Review to estimate the exposure levels and individual susceptibility at low doses DOI
Zhijuan Zhang,

Wenmin Shi,

Lihua Ru

et al.

Toxicology and Industrial Health, Journal Year: 2024, Volume and Issue: 40(9-10), P. 539 - 555

Published: June 12, 2024

Benzene is associated with diverse occupational and public health hazards. It exhibits an ability to rapidly permeate the skin contaminate water food sources, leading dermal ingestion exposures. Despite numerous studies examining associations between benzene various indicators of harm, findings have yielded inconsistent results. Furthermore, relying solely on air concentration as a measure exposure limited, it fails account for internal dose individual susceptibility. This study aimed conduct comprehensive review in order present current knowledge biomarkers their significance evaluating levels The search methodology adhered PRISMA guidelines involved application specific inclusion exclusion criteria across multiple databases including PubMed, Embase, Web Science. Two researchers independently extracted evaluated relevant data based predetermined criteria. Following screening process, total 80 articles were considered eligible out initially retrieved 1053 after undergoing assessment inclusion. As level decreased, demonstrated gradual increase limitations, heightened background concentrations vulnerability confounding factors. advancement sampling analysis techniques will yield new biomarkers. Additionally, when conducting practical work, crucial employ utilization while excluding metabolic variations combined

Language: Английский

Citations

2
Occupational-Related Exposure to Benzene and Risk of Breast Cancer: Systematic Review and Meta-analysis DOI Creative Commons
Vincent DeStefano, Darshi Shah, Veer Shah

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 18, 2024

Abstract Purpose Benzene is a recognized carcinogen; however, its association with breast cancer not well established. Hence, meta-analysis of cohort and case-control studies was performed to determine the between occupational benzene exposure risk cancer. Methods A systematic literature review identified 7221 publications from which 21 were retained evaluated using meta-analyses (fixed effects model). PRISMA guidelines followed. Our protocol registered in PROSPERO database (Registration No. 379720). Study quality assessed modified Newcastle-Ottawa scale (NOS). Results The summary RR for ever-benzene 1.08 (95% CI = 1.02–1.14, I 2 43.6%, n estimates); corresponding incidence mortality 58.6%, 15) 1.09 0.87–1.38, < 0.001%, 9), respectively. These main results confirmed sub-analyses by geography, industry, publication year, levels exposure. No heterogeneity detected amongst geographical regions (p-het 0.19) or industry employment 0.05). However, sex 0.002), year 0.001), study design 0.001). Publication bias (p 0.04). Conclusions an cohorts, regions, durations findings, inability exclude residual confounding, together bias, prevent conclusions causality.

Language: Английский

Citations

2
Occupational Exposure to Benzene and Risk of Breast Cancer: Systematic Review and Meta-Analysis DOI
Monireh Sadat Seyyedsalehi, Vincent DeStefano, Darshi Shah

et al.

˜La œMedicina del lavoro, Journal Year: 2024, Volume and Issue: 115(5), P. e2024034 - e2024034

Published: Oct. 24, 2024

Introduction: Benzene is a recognized carcinogen; however, its association with breast cancer not well established. Hence, meta-analysis of cohort and case-control studies was performed to determine the between occupational benzene exposure risk cancer. Methods: A systematic literature review identified 7573 publications from which 23 were retained evaluated using meta-analyses (fixed effects model). PRISMA guidelines followed. Our protocol registered in PROSPERO database (Registration No. CRD42022379720). Study quality assessed modified Newcastle-Ottawa scale (NOS).Results: The summary relative (RR) for ever-benzene 1.08 (95% CI=1.03-1.14, I2=38.6%, n=23 estimates); corresponding RR incidence mortality CI=1.02-1.14, I2=56.1%, n=16) 1.10 CI=0.87-1.37, I2<0.001%, n=10). However, heterogeneity detected sex (p-het=0.002), publication year (p-het<0.001), study design industry employment (p-het=0.03). high level showed positive 1.35 CI=1.06-1.72, I2 =<0.001%, n=3) (P-het=0.64). Publication bias (p=0.03).Conclusions: results our indicate an increased cancer, particularly when exposed higher levels benzene. confounding could be excluded.

Language: Английский

Citations

1
Direct environmental pollution from solid waste DOI
Ambreen Bano

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 249 - 269

Published: Nov. 15, 2024

Language: Английский

Citations

0
Association between maternal usage of volatile organic compounds and West syndrome, the Japan Environment and Children’s study DOI Creative Commons
Hideki Shimomura,

Naoko Taniguchi,

Tetsuro Fujino

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Dec. 28, 2024

Multiple etiologies of West syndrome have been reported; however, there are cases unknown etiologies. Exposure to volatile organic compounds (VOCs) increases the risk epilepsy; their effects on children remain unknown. This study aimed investigate association between maternal occupational usage VOCs and development in children. Using data from a cohort 88,280 children, we extracted born mothers who had used during pregnancy. Based an epilepsy diagnosis by age 2 years, frequency was comparatively analyzed among following groups: never diagnosed with epilepsy, syndrome, other epileptic syndromes. A total 15, 154, 88,111 were categorized into groups, respectively. The odds ratio (OR) for increased permanent marker (one three times month: OR = 2.58, 95% confidence interval [CI] 0.75–8.90; one or more week: 4.34, CI 1.23–15.26). These results suggested frequent

Language: Английский

Citations

0
Developmental Immunotoxicology – Alternative Methods DOI
Fenna C.M. Sillé

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Language: Английский

Citations

0
Toxicity of chemical-based hand sanitizers on children and the development of natural alternatives: a computational approach DOI
Toshika Mishra, Suneetha Vuppu

Critical Reviews in Toxicology, Journal Year: 2023, Volume and Issue: 53(9), P. 572 - 599

Published: Oct. 21, 2023

The unintended exposure of children to hand sanitizers poses a high risk potentially fatal complications. Skin irritation, dryness, cracking, peeling, hypoglycemia, apnea, and acidosis are examples consequences sanitizer. sanitizer reportedly kills normal microbial flora on hands, which usually promotes innate immunity among under 12. Children more susceptible the toxicity associated with chemical constituents marketed chemical-based sanitizers; however, studies develop formulations for rudimentary. adverse events limit use specifically in because their sensitive delicate skin. Additionally, it is reported that many formulations, especially alcohol-based ones may also contain contaminants like methanol, acetaldehyde, benzene, isopropanol, ethyl-acetate. These found be hazardous human health exhibiting ingestion, inhalation, or dermal exposure, children. Therefore, important design novel, innovative, safer study aims discuss toxic propose novel herbal minimal effects, review focuses ADMET analysis common sanitizers, molecular docking, Lipinski's rule five analysis, simulation analyze efficacy interaction receptor leading anti-microbial activity drug-likeness compound.

Language: Английский

Citations

1
Volatile Organic Compounds Detected in Amniotic Fluid of Women During Normal Pregnancy DOI Creative Commons
Régine Minet‐Quinard, Nicolas Gonçalves-Mendes, Denis Gallot

et al.

Exposure and Health, Journal Year: 2023, Volume and Issue: 16(5), P. 1155 - 1169

Published: Dec. 21, 2023

Abstract Exposure to volatile organic compounds (VOCs) during the fetal period may induce negative effects on children’s health (e.g. increased risk of low birth weight and imbalanced development). Whereas VOCs have been analysed extensively in various human biological fluids (i.e. urine, blood, breath), pregnancy only urine has studied no work performed amniotic fluid (AF), which is direct contact with fetus essential for its well-balanced development maturation. This study aimed detect AF investigate their links lifestyle habits pregnant women. The VOC composition collected from 76 healthy women was using a gas chromatograph coupled mass spectrometer. sources exposure were assessed questionnaire about home living conditions professional exposure. A total 126 belonging 13 chemical families detected AF. majority these (92) had an exogenous origin, presence linked habits, especially smoking fragrance use. Considering multiple organs, this important contribution literature exploring future potential relationships between abnormal development.

Language: Английский

Citations

1