Nutraceuticals in the management of autonomic function and related disorders: A comprehensive review

Pharmacological Research, Journal Year: 2024, Volume and Issue: 208, P. 107368 - 107368

Published: Aug. 25, 2024

Nutraceuticals have been described as phytocomplexes when derived from foods of plant origin or a pool secondary metabolites animal origin, which are concentrated and administered in an appropriate form can promote beneficial health effects the prevention/treatment diseases. Considering that pharmaceutical medications cause side effects, there is growing interest using nutraceuticals adjuvant therapeutic tool for several disorders involving autonomic dysfunction, such obesity, atherosclerosis other cardiometabolic This review summarizes discusses evidence literature on various control, addressing gut microbiota modulation, production bioactive compounds, improvement physical chemical properties cell membranes. Additionally, safety prospects discussed. Probiotics, resveratrol, quercetin, curcumin, nitrate, inositol, L-carnosine, n-3 polyunsaturated fatty acids (n-3 PUFAs) among most studied to improve dysfunction experimental models clinical trials. Further human studies needed elucidate formulated multitarget compounds their underlying mechanisms action, could benefit conditions dysfunction.

Language: Английский

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The role of gut microbiota metabolites in the regeneration and protection of nervous tissue: a narrative review

Regenerative medicine reports ., Journal Year: 2024, Volume and Issue: 1(1), P. 12 - 30

Published: Sept. 1, 2024

The gut microbiota modulates various physiological functions in the human body, including digestion, immune regulation, barrier maintenance, and even nervous system activity. bidirectional communication between microbes brain, known as microbiota–gut–brain axis, is crucial for balanced metabolism. Recent studies have indicated that metabolites, such short-chain fatty acids, indole derivatives, neurotransmitters, other bioactive compounds, can positively impact neurogenesis, myelination, axonal regeneration, suggesting their potential therapeutic strategies neuroprotection neuroregeneration. Despite growing number of on understanding role neuroprotective mechanisms remains limited. This article reviews classification, production, most well-known well synaptogenesis, energy metabolism, modulation, blood–brain integrity, which will provide a foundation study metabolites field biomedical engineering.

Language: Английский

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The emerging roles of neuroactive components produced by gut microbiota

Molecular Biology Reports, Journal Year: 2024, Volume and Issue: 52(1)

Published: Nov. 21, 2024

Language: Английский

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The role of gut microbiota in the development of salt-sensitive hypertension and the possible preventive effect of exercise

Expert Review of Cardiovascular Therapy, Journal Year: 2024, Volume and Issue: 22(6), P. 265 - 271

Published: June 1, 2024

Introduction The aim of the present study is to analyze data indicating an association between high salt intake and gastrointestinal microbiota in development sensitive hypertension animals man. It also, discuss preventive effects exercise on gut-induced by favorably modifying composition gut microbiota.

Language: Английский

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Clinicopathological findings in cats with haws syndrome

Veterinary Record, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 12, 2024

Haws syndrome is a relatively common yet poorly understood disorder in cats.

Language: Английский

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Latest Review Papers in Molecular Microbiology

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(18), P. 13990 - 13990

Published: Sept. 12, 2023

This Special Issue—dedicated to high-quality review papers in molecular microbiology—is highlighting two important developments the field: (i) analysis of microbiome data health and disease (ii) search for strategies against bacteria showing antimicrobial resistance [...]

Language: Английский

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