Bio-Inspired Nanomaterials for Micro/Nanodevices: A New Era in Biomedical Applications

Micromachines, Journal Year: 2023, Volume and Issue: 14(9), P. 1786 - 1786

Published: Sept. 18, 2023

Exploring bio-inspired nanomaterials (BINMs) and incorporating them into micro/nanodevices represent a significant development in biomedical applications. Nanomaterials, engineered to imitate biological structures processes, exhibit distinctive attributes such as exceptional biocompatibility, multifunctionality, unparalleled versatility. The utilization of BINMs demonstrates potential diverse domains micro/nanodevices, encompassing biosensors, targeted drug delivery systems, advanced tissue engineering constructs. This article thoroughly examines the various BINMs, including those originating from proteins, DNA, biomimetic polymers. Significant attention is directed toward these entities subsequent ramifications that arise. review explores biomimicry’s structure–function correlations. Synthesis mosaics include bioprocesses, biomolecules, natural structures. These nanomaterials’ interfaces use functionalization geometric adaptations, transforming delivery, nanobiosensing, organ-on-chip cancer-on-chip models, wound healing dressing mats, antimicrobial surfaces. It provides an in-depth analysis existing challenges proposes prospective strategies improve efficiency, performance, reliability devices. Furthermore, this study offers forward-thinking viewpoint highlighting avenues for future exploration advancement. objective effectively utilize maximize application progression thereby propelling rapidly developing field its promising future.

Language: Английский

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Chitosan and Its Derivatives: Preparation and Antibacterial Properties

Materials, Journal Year: 2023, Volume and Issue: 16(18), P. 6076 - 6076

Published: Sept. 5, 2023

This comprehensive review illuminates the various methods of chitosan extraction, its antibacterial properties, and multifarious applications in diverse sectors. We delve into chemical, physical, biological, hybrid, green extraction techniques, each which presents unique advantages disadvantages. The choice method is dictated by multiple variables, including desired properties chitosan, resource availability, cost, environmental footprint. explore intricate relationship between chitosan’s activity such as cationic density, molecular weight, water solubility, pH. Furthermore, we spotlight burgeoning chitosan-based materials like films, nanoparticles, nonwoven materials, hydrogels across food, biomedical, agricultural concludes highlighting promising future underpinned technological advancements growing sustainability consciousness. However, critical challenges optimizing production for efficiency remain to be tackled.

Language: Английский

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Biopolymer based nanoparticles and their therapeutic potential in wound healing – A review

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 267, P. 131335 - 131335

Published: April 10, 2024

Language: Английский

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Activity and safety evaluation of natural preservatives

Food Research International, Journal Year: 2024, Volume and Issue: 190, P. 114548 - 114548

Published: May 29, 2024

Language: Английский

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Chitosan‐Based Hydrogels as Antibacterial/Antioxidant/Anti‐Inflammation Multifunctional Dressings for Chronic Wound Healing

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 13(30)

Published: July 22, 2024

Abstract Due to repeated microbial infection, persistent inflammation, excessive oxidative stress, and cell dysfunction, chronic wounds are difficult heal, posing a serious threat public health. Therefore, developing multifunctional wound dressings that can regulate the complex microenvironment of enhance cellular function holds great significance. Recently, chitosan has emerged as promising biopolymer for healing due its excellent biocompatibility, biodegradability, versatile bioactivity. The aim this review is provide comprehensive understanding mechanisms delayed discuss healing–promoting properties derivatives, such good antibacterial activity, hemostatic capacity, ability promote tissue regeneration. On basis, potential applications chitosan‐based hydrogels summarized in healing, including providing suitable microenvironment, eliminating bacterial infections, promoting hemostasis, inhibiting alleviating In addition, concerns perspectives clinical application also discussed.

Language: Английский

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Synthesis and characterization of a novel magnetic chitosan–nickel ferrite nanocomposite for antibacterial and antioxidant properties

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: Sept. 22, 2023

A novel nanomagnet modified with nickel ferrite nanoparticles (NPs) coated hybrid chitosan (Cs-NiFe2O4) was synthesized using the co-precipitation method. The resulting nanomagnets were characterized various techniques. size of nanomagnetic particles estimated to be about 40 nm based on transmission electron microscopy (TEM) image and X-ray diffraction analysis (XRD) pattern (using Debye-Scherrer equation). Scanning (SEM) images indicated that surface Cs-NiFe2O4 NPs is flatter smoother than uncoated NiFe2O4 NPs. According value stream mapping (VSM) analysis, magnetization (17.34 emu/g) significantly lower (40.67 emu/g). higher antibacterial properties Cs. minimum inhibitory concentrations against S. aureus E. coli 128 256 mg/mL, respectively. Antioxidant activity (evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging test) for at concentration 100 µg/mL 35% 42%, Consequently, can proposed as a viable material biomedical applications.

Language: Английский

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Polysaccharide-Based Coatings as Drug Delivery Systems

Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(9), P. 2227 - 2227

Published: Aug. 29, 2023

Therapeutic polysaccharide-based coatings have recently emerged as versatile strategies to transform a conventional medical implant into drug delivery system. However, the translation of these clinic systems still requires deeper understanding their degradation/release profiles. This claim is supported by little or no data. In this review paper, comprehensive description benefits and challenges generated provided. Moreover, latest advances made towards application most important representative based on polysaccharide types for are debated. Furthermore, suggestions/recommendations future research speed up transition from laboratory testing clinical applications given.

Language: Английский

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Development of chitosan-based edible film incorporated with purified flavonoids from Moringa oleifera: Structural, thermal, antibacterial activity and application

Food Chemistry, Journal Year: 2024, Volume and Issue: 457, P. 140059 - 140059

Published: June 12, 2024

Language: Английский

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Microwave Assisted Extraction of Chitosan from Agaricus bisporus: Techno-Functional and Microstructural Properties

Carbohydrate Polymer Technologies and Applications, Journal Year: 2025, Volume and Issue: unknown, P. 100730 - 100730

Published: Feb. 1, 2025

Language: Английский

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Synergistic chitin-zinc nanocomposites from shrimp shell waste: characterization, antioxidant, and antibacterial properties

Biomass Conversion and Biorefinery, Journal Year: 2023, Volume and Issue: unknown

Published: Dec. 23, 2023

Language: Английский

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