Hydrogen sulfide signaling in plant response to temperature stress

Frontiers in Plant Science, Journal Year: 2024, Volume and Issue: 15

Published: March 13, 2024

For the past 300 years, hydrogen sulfide (H 2 S) has been considered a toxic gas. Nowadays, it found to be novel signaling molecule in plants involved regulation of cellular metabolism, seed germination, plant growth, development, and response environmental stresses, including high temperature (HT) low (LT). As molecule, H S can actively synthesized degraded cytosol, chloroplasts, mitochondria cells by enzymatic non-enzymatic pathways maintain homeostasis. To date, receptors for have not found. It usually exerts physiological functions through persulfidation target proteins. In 10 gained much attention. Therefore, this review, based on that same attention, homeostasis, protein persulfidation, role HT LT stress were summarized. Also, common mechanisms S-induced tolerance updated. These involve restoration biomembrane integrity, synthesis proteins, enhancement antioxidant system methylglyoxal (MG) detoxification system, improvement water homeostasis reestablishment Ca 2+ acid-base balance. updates lay foundation further understanding acquiring temperature-stress-resistant crops develop sustainable food agriculture.

Language: Английский

Hydrogen Sulfide and Irisin, Potential Allies in Ensuring Cardiovascular Health

Antioxidants, Journal Year: 2024, Volume and Issue: 13(5), P. 543 - 543

Published: April 28, 2024

Irisin is a myokine secreted under the influence of physical activity and exposure to low temperatures through different exogenous stimuli by cleavage its precursor, fibronectin type III domain-containing protein 5 (FNDC5). It mainly known for maintaining metabolic homeostasis, promoting browning white adipose tissue, thermogenesis process, glucose homeostasis. Growing experimental evidence suggests possible central role irisin in regulation cardiometabolic pathophysiological processes. On other side, hydrogen sulfide (H2S) well recognized as pleiotropic gasotransmitter that regulates several homeostatic balances physiological functions takes part pathogenesis diseases. Through S-persulfidation cysteine residues, H2S capable interacting with crucial signaling pathways, exerting beneficial effects regulating lipid homeostasis well. seem be intertwined; indeed, recently, was found regulate secretion activating peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α)/FNDC5/irisin pathway, they share mechanisms action. Their involvement diseases confirmed detection their lower circulating levels obese diabetic subjects. Along importance disorders, these modulators exert favorable against cardiovascular diseases, preventing incidents hypertension, atherosclerosis, heart failure, myocardial infarction, ischemia–reperfusion injury. This review, first time, aims explore crosstalk pointing out main exerted common molecular pathways involved.

Language: Английский

Anti‐obesity effects of Beta vulgaris and Eruca sativa‐based extracts

Phytotherapy Research, Journal Year: 2024, Volume and Issue: 38(9), P. 4757 - 4773

Published: Aug. 9, 2024

Obesity is a major source of morbidity worldwide with more than 2 billion adults being overweight or obese. The incidence obesity has tripled in the last 50 years, leading to an increased risk for variety noncommunicable diseases. Previous studies have demonstrated positive effects green leafy vegetables on weight gain and attributed these beneficial properties, at least part, nitrates isothiocyanates. Nitrates are converted nitric oxide (NO) isothiocyanates known release hydrogen sulfide (H

Language: Английский