The Nano Revolution, Metal Nanoparticles in Antibiotic-Resistant Era DOI

Shilpa Rudra,

Danie Kingsley

IGI Global eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 91 - 142

Published: April 25, 2025

Nanoparticle synthesis has gained significant interest over the years because of its unique characteristics and sustainable productive applications in numerous fields. Metals exhibiting a friend-foe relationship with bacteria, possess potential to inhibit their growth specific forms concentrations. The increase antimicrobial resistance recent drawn attention. Top-down Bottom-up are two approaches metal nanoparticle synthesis. Gold, silver, copper, etc. have been used medical fields from ancient times. Although these conventional methods creating nanoparticles effective adaptable, they very negative effects. On other hand, green provides an economical environmentally beneficial substitute by using natural resources. To address current problem resistance, this review highlights activity contributions sustainability, safety efficiency production as well process, benefits, drawbacks.

Language: Английский

Advances in the Optimization of Fe Nanoparticles: Unlocking Antifungal Properties for Biomedical Applications DOI Creative Commons

Zeshan Ali Sandhu,

Muhammad Asam Raza, Abdulmajeed Alqurashi

et al.

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(5), P. 645 - 645

Published: May 10, 2024

In recent years, nanotechnology has achieved a remarkable status in shaping the future of biological applications, especially combating fungal diseases. Owing to excellence nanotechnology, iron nanoparticles (Fe NPs) have gained enormous attention years. this review, we provided comprehensive overview Fe NPs covering key synthesis approaches and underlying working principles, factors that influence their properties, essential characterization techniques, optimization antifungal potential. addition, diverse kinds NP delivery platforms command highly effective release, with fewer toxic effects on patients, are great significance medical field. The issues biocompatibility, toxicity profiles, applications optimized field biomedicine also been described because these most significant determining inclusion clinical use. Besides this, difficulties regulations exist transition from laboratory experimental studies (toxicity, specific standards, safety concerns) NPs-based agents summarized.

Language: Английский

Citations

7

Chemo-photothermal therapy of chitosan/gold nanorod clusters for antibacterial treatment against the infection of planktonic and biofilm MRSA DOI

G.R. Nirmal,

Zih‐Chan Lin,

Tai‐Sheng Chiu

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 268, P. 131673 - 131673

Published: April 19, 2024

Language: Английский

Citations

5

AMP-Mimetic Antimicrobial Polymer-Involved Synergic Therapy with Various Coagents for Improved Efficiency DOI

Yiyu Gong,

Hepeng Wang,

Jing Sun

et al.

Biomacromolecules, Journal Year: 2024, Volume and Issue: 25(8), P. 4619 - 4638

Published: May 8, 2024

The misuse of antibiotics contributes to the emergence multidrug-resistant (MDR) bacteria. Infections caused by MDR bacteria are rapidly evolving into a significant threat global healthcare due lack effective and safe treatments. Antimicrobial peptides (AMPs) with broad-spectrum antibacterial activity kill generally through membrane disruption mechanism; hence, they tend not induce resistance readily. However, AMPs exhibit disadvantages, such as high cost susceptibility proteolytic degradation, which limit their clinical application. AMP-mimetic antimicrobial polymers, low cost, stability proteolysis, activity, negligible resistance, rapid bactericidal effect, have received extensive attention new type drugs. Lately, polymer-involved synergic therapy provides superior alternative combat distinct mechanisms. In this Review, we summarize polymers involved in therapy, particularly focusing on different combinations between commercially available antimicrobials, organic small molecule photosensitizers, inorganic nanomaterials, nitric oxide.

Language: Английский

Citations

5

Green synthesis of Brassica carinata microgreen silver nanoparticles, characterization, safety assessment, and antimicrobial activities DOI Creative Commons

Dogfounianalo Somda,

Joel L. Bargul, John Wesonga

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Nov. 26, 2024

Nanotechnology has been a central focus of scientific investigation over the past decades owing to its versatile applications. The synthesis silver nanoparticles (AgNPs) through plant secondary metabolites is cost-effective and eco-friendly approach. present study employed Brassica carinata microgreen extracts (BCME) promote reduction nitrate (AgNO

Language: Английский

Citations

5

Unlocking the potential of titanium dioxide nanoparticles: an insight into green synthesis, optimizations, characterizations, and multifunctional applications DOI Creative Commons
Ahmed Ghareeb, Amr Fouda, Rania Kishk

et al.

Microbial Cell Factories, Journal Year: 2024, Volume and Issue: 23(1)

Published: Dec. 23, 2024

This comprehensive review explores the emergence of titanium dioxide nanoparticles (TiO

Language: Английский

Citations

4

Royal Jelly: A Novel Biotemplate for the Green Synthesis of Antibacterial Metal Nanoparticles DOI
Seyed Mohammad Mahdi Dadfar,

Fatemeh-Sadat Hashemirad,

Gholamreza Kavoosi

et al.

Published: Jan. 1, 2025

The application of green synthesis in nanotechnology is rapidly expanding as a safe and eco-friendly alternative to conventional methods. This study explored the potential royal jelly bio-reducing agent for synthesizing metal nanoparticles evaluated their antibacterial activity. Royal exhibited strong antioxidant activity, demonstrated by ABTS (2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonate)) DPPH (2,2-diphenyl-1-picrylhydrazyl) assays, comparable that Trolox. However, it showed weak effects against both Gram-positive Gram-negative bacteria. Using jelly, silver, iron, copper, zinc were synthesized, confirmed Fourier Transform Infrared Spectrometer (FTIR), ultraviolet-visible (UV-Vis), fluorescence spectroscopy, morphological analyses. significant disrupting bacterial cell walls killing bacteria, shown inhibition zone minimum inhibitory concentrations (MIC), bactericidal (MBC), scanning electron microscope (SEM) imaging. research highlights jelly's dual role reducing nanoparticle its applications.

Language: Английский

Citations

0

Effect of stabilizers on composition and stability of bimetallic copper/silver nanoparticles DOI
Kateryna Bryleva, Zinaida Bunina, Victoria Varchenko

et al.

Journal of Nanoparticle Research, Journal Year: 2025, Volume and Issue: 27(3)

Published: Feb. 20, 2025

Language: Английский

Citations

0

Gold nanoparticle mediated approaches for wound healing DOI
Adalberto Zamudio‐Ojeda, Santiago José Guevara-Martínez, J.G. Quiñones-Galván

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 241 - 262

Published: Jan. 1, 2025

Language: Английский

Citations

0

Ciprofloxacin-loaded copper oxide nanoparticles: Cutting-edge multifunctional nano-therapeutics with superior antidiabetic, antioxidant, anti-inflammatory, and antibacterial potency against drug-resistant pathogens DOI

Ibtissam Laib,

Abderrhmane Bouafia, Salah Eddine Laouini

et al.

Journal of Crystal Growth, Journal Year: 2025, Volume and Issue: unknown, P. 128074 - 128074

Published: Jan. 1, 2025

Language: Английский

Citations

0

Characterisation and visible light induced antibacterial activity of Cu-doped zinc oxide nanoparticles DOI

Saba Behfar,

Mohammad Ghorbanpour, Mohammed Jaafar Ali Alatabe

et al.

Indian Chemical Engineer, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 10

Published: Jan. 29, 2025

Language: Английский

Citations

0