Associations between urinary parabens and thyroid hormone homeostasis across trimesters in Taiwanese pregnant women

Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 291, P. 117818 - 117818

Published: Jan. 30, 2025

Language: Английский

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Occupational exposure to hairdressing products and thyroid disrupting effects : protocol for an exploratory field study in French hairdressers (Preprint)

Published: March 14, 2025

Cosmetic legislation is ensuring the safety of cosmetics for consumers but not professional use. All around world, hairdressing sector constitutes a major occupational group including about 90% women continuously exposed to numerous chemical composing products, among them endocrine disrupting compounds such as resorcinol, parabens, phtalates, UV filters. The thyroid-disrupting chemicals are substances concern incidence thyroid dysfunction has increased recently worldwide and long-term consequences at neurodevelopmental level in offspring after in-utero expoure were highlighted. Few biomonitoring studies explored exposure disruptors hairdressers up date we found no data impact on hormones system. present study aimed assess resorcinol French analyze relationship with biological parameters, taking into account other (parabens, filters). A cross-sectional carried out 300 female aged 18-45 years compared 150 controls, who recruited by six health services. followed during 5-day working week individual salon levels (urinary (resorcinol, benzophenone-3, ethylhexyl methoxycinnamate’s metabolits) different time points, daily job tasks use hair inventory products) blood parameters (T3, T4, TSH, thyroglobulin, thyroperoxidase throglobulin antibodies). Information sociodempographics residence, alimentary tobacco consumption, personal care household career medical history was collected questionnaire. inclusion population planned between 2023 2025. Until now, total XX subjects (XX belonging salons, unexposed) included Since rates salons (around 10%) 50%), below those estimated, period will be extended till 2026. Further, new partnership more services under study. This provide evidence disruptors. results represent first France hairdressers, susceptible childbearing age. We proposed timely research based professionals designed following multidisciplinary approach biometrology epidemiology. collection both allow in-depth assessment workplace. Together these may strengthen tools risk diagnosis prevention salons.

Language: Английский

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Transgenerational Thyroid Hormone Disruption in Zebrafish Induced by Environmentally Relevant Concentrations of Triclosan

Environmental Pollution, Journal Year: 2025, Volume and Issue: unknown, P. 126242 - 126242

Published: April 1, 2025

Language: Английский

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Exploring the binding mechanism of parabens to transthyretin: An integrated analysis using multi-spectral and computational simulation techniques

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2025, Volume and Issue: 339, P. 126265 - 126265

Published: April 18, 2025

Language: Английский

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Exposure assessment of dairy cows to parabens using hair samples analysis

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: June 21, 2024

Parabens (PBs) are used as preservatives in various products. They pollute the environment and penetrate living organisms, showing endocrine disrupting activity. Till now studies on long-term exposure of farm animals to PBs have not been performed. Among matrices using biomonitoring hair samples becoming more important. During this study concentration levels methyl paraben (MeP), ethyl (EtP), propyl (PrP) butyl (BuP) benzyl (BeP) were evaluated liquid chromatography-mass spectrometry (LC-MS) collected from dairy cows bred Kyrgyz Republic. MeP was noted 93.8% (with mean 62.2 ± 61.8 pg/mg), PrP 16.7% (12.4 6.5 pg/mg) EtP 8.3% (21.4 11.9 pg/mg). BuP found only one sample (2.1%) BeP detected any included study. Some differences depending district, where noted. This has shown that among PBs, exposed mainly MeP, may be a suitable matrix for research animals.

Language: Английский

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Additives in Processed Foods as a Potential Source of Endocrine-Disrupting Chemicals: A Review

Journal of Xenobiotics, Journal Year: 2024, Volume and Issue: 14(4), P. 1697 - 1710

Published: Nov. 4, 2024

Processed foods, accounting for most consumable food categories today, contain considerable amounts of additives. Food additives are substances added to products improve taste, consistency, appearance, or shelf life. Various additives, such as phthalates, bisphenol A, tartrazine, erythrosine, artificial sweeteners, and parabens, have been identified potential sources endocrine-disrupting chemicals (EDCs) in processed foods. EDCs that frequently interfere with the regular functioning endocrine system, creating an unusual environment biological which leads adverse health effects disruption hormone synthesis, receptor binding, signal transduction pathways, well energy metabolic homeostatic disorders potentially increasing risk obesity, type-2 diabetes, cardiometabolic diseases may also trigger allergic reactions. Consequently, they can impact mammary gland development, reproductive function, further leading developmental abnormalities. This review aims insights into various act describe their applications industry, failure hormonal mechanisms, eventually result hazardous effects. It outlines strategies reduce use suggests alternative minimal no properties, highlighting importance maintaining human health.

Language: Английский

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Urinary haloacetic acid concentrations and thyroid function among women: Results from the TREE study

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 927, P. 172368 - 172368

Published: April 12, 2024

Language: Английский

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Bioaccumulation and ecotoxicity of parabens in aquatic organisms: Current status and trends

Environmental Pollution, Journal Year: 2024, Volume and Issue: unknown, P. 125213 - 125213

Published: Oct. 1, 2024

Language: Английский

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Evolution of microbial community and resistance genes in denitrification system under single and combined exposure to benzethonium chloride and methylparaben

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 480, P. 136010 - 136010

Published: Sept. 30, 2024

Language: Английский

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Blood levels of zearalenone, thyroid-stimulating hormone, and thyroid hormones in patients with colorectal cancer

Toxicon, Journal Year: 2024, Volume and Issue: 251, P. 108125 - 108125

Published: Oct. 10, 2024

Mycotoxins are secondary metabolites produced by various species of mold fungi commonly found in plant materials. Zearalenone (ZEN) adversely affects the endocrine system. This study aimed to determine whether thyroid-stimulating hormone (TSH), procalcitonin (PCT), free triiodothyronine (fT3), and thyroxine (fT4) levels altered during natural zearalenone mycotoxicosis patients diagnosed with sigmoid colon cancer (SCC) or colorectal (CRC). A was conducted on women men SCC CRC accompanied presence absence (Patients Without ZEN - PWZ group) blood. The group consisted 17 symptoms whom its were not detected peripheral experimental (empirical) groups included a total 16 who tested positive for ZEN, but metabolites. TSH values both sexes within upper limit reference range (0.27-4.2 μIU/mL) adopted hospital laboratory corresponded second tertile lower third tertile. PCT demonstrated that systemic local bacterial infection. All mean fT3 middle range, fT4 limit. fT3/fT4 prognostic marker somewhat above cut-off point 0.22. These results indicate postmenopausal andropausal exposed food-borne higher (fT3/fT4) associated an unfavorable prognosis. also revealed more distal neoplastic lesions colon, percentage thyroid hormones, regardless patient's sex. diet alters activity CRC.

Language: Английский

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