Calcium channels as pharmacological targets for cancer therapy

Clinical and Experimental Medicine, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 25, 2025

Language: Английский

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Cannabis User Perceptions: General and Oral Health Benefits and Harms of Vaping Versus Smoking

Substance Use & Misuse, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 7

Published: April 16, 2025

With increasing popularity of vaping, the study assessed perceptions adults who used cannabis/marijuana about general and oral health benefits harms vaping compared to smoking cannabis. An online cross-sectional survey was conducted with a convenience sample (n = 324) had cannabis in past month recruited via Amazon Mechanical Turk (MTurk). Survey items included or cannabis/marijuana. Descriptive, correlation, non-parametric analysis were used. The completion rate 93.2% 302). most important benefit reported for better pain management (72.5%). harm identified both it being habit forming. Researching associated more likely report higher risk cardiovascular disease (Phi effect size 0.141) cavities (tooth decay; Phi 0.15). Women preferred improve mood (p 0.016) younger age preference reduce stress, anxiety, depression 0.03). findings expanded knowledge on new information related health. There few significant differences from as However, highlight importance an interprofessional collaboration provide evidence-based potential impact

Language: Английский

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How Biodegradable Polymers Can be Effective Drug Delivery Systems for Cannabinoids? Prospectives and Challenges

International Journal of Nanomedicine, Journal Year: 2024, Volume and Issue: Volume 19, P. 4607 - 4649

Published: May 1, 2024

Abstract: Cannabinoids are compounds found in and derived from the Cannabis plants that have become increasingly recognised as significant modulating factors of physiological mechanisms inflammatory reactions organism, thus inevitably affecting maintenance homeostasis. Medical popularity has surged since its legal regulation growing around world. Numerous promising discoveries bring more data on cannabinoids' pharmacological characteristics therapeutic applications. Given current surge interest medical use cannabinoids, there is an urgent need for effective method their administration. Surpassing low bioavailability, water solubility, instability became important milestone advancement cannabinoids pharmaceutical The numerous uses clinical practice remain restricted by limited administration alternatives, but hope when biodegradable polymers taken into account. primary objective this review to highlight wide range indications which may be used, well polymeric carriers enhance effectiveness. described a applications including pain management, neurological sleep disorders, anxiety, cancer treatment. these was further examined area dermatology cosmetology. Finally, with polymer-based drug delivery systems (DDSs), it demonstrated can delivered specifically intended site while also improving drug's physicochemical properties, emphasizing utility. Nevertheless, additional trials novel formulations required, full spectrum therapeutical potential yet unravelled. Keywords: systems, cannabidiol, tetrahydrocannabinol, polymers, nanomedicine

Language: Английский

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The role of THC and CBD in dentistry – a review of impacts on oral health

Journal of Pre-Clinical and Clinical Research, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 8, 2024

1. Grotenhermen F. Pharmacokinetics and pharmacodynamics of cannabinoids. Clin Pharmacokinet. 2003;42(4):327–60. doi:10.2165/00003088-200342040-00003. PMID: 12648025. CrossRef Pubmed Google Scholar

Language: Английский

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