Molecular tools for genome editing in plants: a synthetic overview

Vegetable Research, Journal Year: 2025, Volume and Issue: 5(1), P. 0 - 0

Published: Jan. 1, 2025

Language: Английский

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From Gene Editing to Tumor Eradication: The CRISPR Revolution in Cancer Therapy

Progress in Biophysics and Molecular Biology, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

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Enhancing Crop Nutrition in Arid and Semiarid Regions of Africa Through Genome Editing Using CRISPR/Cas

Food and Energy Security, Journal Year: 2025, Volume and Issue: 14(3)

Published: April 25, 2025

ABSTRACT Food insecurity is a pressing issue in Africa, aggravated by escalating drought, jeopardizing the region's ability to meet nutritional requirements for human health. In arid and semiarid regions, crop yield severely affected drought salinity. Thus, obtaining an effective development requires striking right balance between growth defense. This review delves into potential of CRISPR/Cas genome editing technology tackle these challenges improving quality climate‐resilient crops SSA context soil We describe detail opportunities with traits that could be developed using systems cultivation regions Africa. discussed crops, genes specific pathways targeted. Furthermore, we emphasize importance aligning scientific solutions evolving policy frameworks, particularly favorable biosafety regulations concerning editing. addition, underscore significance capacity‐building programs, which have revolutionize value chains, tapping enabled through By strategically integrating supporting policies alongside initiatives communication strategies, Africa can bolster food security amidst climate change challenges. approach not only addresses immediate needs but also fosters long‐term resilience agricultural systems.

Language: Английский

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How Helpful May Be a CRISPR/Cas-Based System for Food Traceability?

Published: Aug. 28, 2024

Crops obtained by genome editing (GE) technologies represent a notable and disruptive shift from genetically modified or transgenic plants, outpacing public perception regulatory frame-works. Multiple aspects of GE are contributing to the advancement modern agriculture, in-fluencing market structure introducing specific changes within existing genetic blue-print an organism. Generally, toolbox includes distinct able incorporate site-specific pre-determined genomic modifications, exploiting well-established modification strategies. For these reasons, GE-derived approaches considered new plant breeding methods, known as techniques (NBTs). Particularly, CRISPR/Cas-based considerable improvement over prior techniques, being more precise, accurate straightforward for targeted gene editing, in reliable reproducible way, with numerous applications. CRISPR/Cas system exploitation non-editing purposes has also been widely documented, ranging cell imaging expression regulation DNA assembly. Recently, systems have employed target detection could be used ef-ficiently identify multiple organic chemicals. High-sensitivity high-specificity two main points technology, without needing complex expertise technical pipelines. This manuscript aims provide overview advances into frontiers non-editing. The associated implications (e.g., molecular traceability) their relative impacts presented discussed.

Language: Английский

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How Helpful May Be a CRISPR/Cas-Based System for Food Traceability?

Foods, Journal Year: 2024, Volume and Issue: 13(21), P. 3397 - 3397

Published: Oct. 25, 2024

Genome editing (GE) technologies have the potential to completely transform breeding and biotechnology applied crop species, contributing advancement of modern agriculture influencing market structure. To date, GE-toolboxes include several distinct platforms able induce site-specific predetermined genomic modifications, introducing changes within existing genetic blueprint an organism. For these reasons, GE-derived approaches are considered like new plant methods, known also as New Breeding Techniques (NBTs). Particularly, GE-based on CRISPR/Cas technology represents a considerable improvement forward biotech-related techniques, being highly sensitive, precise/accurate, straightforward for targeted gene in reliable reproducible way, with numerous applications food-related plants. Furthermore, examples system exploitation non-editing purposes, ranging from cell imaging expression regulation DNA assembly, increasing, together recent engagements target multiple chemical detection. This manuscript aims, after providing general overview, focus attention main advances CRISPR/Cas-based systems into frontiers non-editing, presenting discussing associated implications their relative impacts molecular traceability, aspect closely related food safety, which increasingly arouses interest public opinion scientific community.

Language: Английский

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CRISPR/Cas: a toolkit for plant disease diagnostics

Trends in Plant Science, Journal Year: 2024, Volume and Issue: 30(3), P. 245 - 248

Published: Dec. 17, 2024

Language: Английский

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