Selenium nanoparticles enhance metabolic and nutritional profile in Phaseolus vulgaris: comparative metabolomic and pathway analysis with selenium selenate

BMC Plant Biology, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 28, 2025

Abstract Selenium is a beneficial element in agriculture, particularly for its potential to improve plant growth and stress tolerance at suitable concentrations. In this study, Phaseolus vulgaris was foliar-sprayed with selenium selenate (Se) or nanoparticles (SeNP) different concentrations during the vegetative stage; afterward, seed yield analyzed metabolomics using 1 H, J -resolved HSQC NMR data, databases. A total of 47 metabolites were identified sugars being major chemical class. control sample, most abundant sugar stachyose (14.6 ± 0.8 mM). Among alkaloids, concentration trigonelline highest (0.6 0.08 Chemometric cluster analyses distinctly differentiated from Se SeNP-treated samples. Treatments SeNP resulted elevated sugars, carboxylic acids, sulfur-containing amino acids compared treated Conversely, betaine levels higher The presence significantly decreased several aliphatic e.g. alanine. addition 50 µM upregulated syringate by 2-fold 1.75-fold, respectively, relative control. Pathway analysis indicated altered pathways due arginine biosynthesis nitrogen metabolism. influenced glyoxylate dicarboxylate metabolism as well glycine-serine threonine This study proved that are more efficient than enhancing metabolic profile which will have implications agricultural practices, focusing on sustainability nutritional enhancement crops.

Language: Английский

---

Coffee consumption, cancer, and healthy aging: epidemiological evidence and underlying mechanisms

GeroScience, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 13, 2024

Language: Английский

---

Hybrid hydrogel loaded with natural plant extract accelerates diabetic wound healing via ROS scavenging and immunoregulation

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: unknown, P. 156388 - 156388

Published: Oct. 1, 2024

Language: Английский

---

Compositional analysis of baru (Dipteryx alata Vog.) pulp highlighting its industrial potential

Food Research International, Journal Year: 2025, Volume and Issue: 201, P. 115548 - 115548

Published: Jan. 2, 2025

Language: Английский

---

Development and validation of an eco-friendly, stability-indicating UV spectroscopic method for trigonelline analysis in nanoformulation using quality by design approach

Analytical Chemistry Letters, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 16

Published: Jan. 8, 2025

Language: Английский

---

Green technologies applied to extraction processes and analysis of polyphenolic compounds from Inga laurina Willd

Food Chemistry, Journal Year: 2025, Volume and Issue: 471, P. 142827 - 142827

Published: Jan. 11, 2025

Language: Английский

---

Integrating proteomics and metabolomics to elucidate the regulatory mechanisms of pimpled egg production in chickens

Poultry Science, Journal Year: 2025, Volume and Issue: 104(2), P. 104818 - 104818

Published: Jan. 15, 2025

Language: Английский

---

Synthesis of Small Molecule Library of Novel Nicotinamide Derivatives as Anticancer Agents and Computational Screening

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(3)

Published: Jan. 1, 2025

Abstract A small molecule library of nicotinamide derivatives synthesized and characterized their structure by interpretation 1 H NMR, 13 C Mass spectral data. The new molecules were screened for in vitro anticancer activity against human breast (MCF‐7) cervical (HeLa) cell lines using Doxorubicin as standard reference. Pyridine linked displayed potent both the lines. trifluoromethyl substituted pyridine analogue demonstrated outstanding with IC 50 value 8.70 ± 0.23 µM 8.97 0.31 MCF‐7 HeLa respectively, respect to 9.06 0.36 9.17 0.39 (HeLa). compound 6 thiomethyl group 9.01 0.38 9.82 0.41 correspondingly. methyl 5h encouraging 10.47 11.87 0.45 Molecular docking study performed , 5i, estrogen receptor alpha (PDB ID: 3ERT), obtained highest score ligand 5i (9.5 kcal/mol). predicted ADME compounds indicated drug‐like characteristics.

Language: Английский

---

Combination of ultrasound and supercritical carbon dioxide extraction for trigonelline production from Quisqualis indica

Ultrasonics Sonochemistry, Journal Year: 2025, Volume and Issue: unknown, P. 107317 - 107317

Published: March 1, 2025

Trigonelline is a natural alkaloid with important nutrient benefits. A hybrid technique adopting ultrasound-assisted supercritical CO2 extraction (UASCE) was exploited for of trigonelline from Quisqualis indica. Response surface methodology used to optimize operational parameters the UASCE process, which indicated that highest yield (TY), 4.22 ± 0.06 mg/g dry mass, reached at 62 °C temperature, 26 MPa pressure, 13.5 wt% co-solvent concentration, and 0.16 W/mL ultrasonic energy density. When compared traditional extraction, yielded higher TY more quickly while using milder conditions producing antioxidant capacity concentrations phytochemicals (alkaloids, flavonoids, triterpenoids) extract. Microstructural observation showed extensive micro-fractures formed in UASCE-processed samples may have positive effects on solutes liberation. Furthermore, kinetic study revealed developed Sovová models matched measured results. The impetus derived primarily convection mechanism. Ultrasound increased rates mass transfer coefficients shortened characteristic periods. Additionally, correlated Chrastil equation determination solubility under varying conditions. model reflected actual solubilities satisfactorily typical crossover phenomenon observed. can effectively promote CO2. In conclusion, sustainable high-performance procedure produce high-quality trigonelline-rich extracts. This paper provides new work about industrial production design future. indica serves as prospective source acquisition.

Language: Английский

---

Characterization of bioactive compounds in fenugreek genotypes in varying environments: diosgenin, trigonelline, and 4-hydroxyisoleucine

Frontiers in Plant Science, Journal Year: 2025, Volume and Issue: 16

Published: March 24, 2025

This study investigates the effects of irrigated and non-irrigated conditions on bioactive compound content in fenugreek ( Trigonella foenum-graecum ) across 31 diverse genotypes from various geographical regions. The was conducted at Atatürk University Research Extension Center, Türkiye (N 39°55’59.9”, E 41°14’10.6”, altitude 1789 m) during 2021 2022 growing seasons. levels diosgenin, trigonelline, 4-hydroxyisoleucine analyzed under were found to be significantly influenced by genotype, environment, their interaction (Genotype × Environment), with a highly significant effect observed p < 0.001 level. compounds included diosgenin (0.50-0.93%), trigonelline (5.22-13.65 mg g - ¹), (0.41-1.90%). Notably, such as Sivas/TR, Amasya/TR, Konya/TR Samsun/TR exhibited higher all conditions, while Spain, Malaysia, France, India showed irrigation. Variability observed, some showing stability different environmental conditions. A negative correlation between fenugreek. Furthermore, Principal Component Analysis (PCA) cluster analysis effective revealing genetic diversity, morphological differences, genotype adaptability. findings highlight potential for selecting superior breeding programs focused enhancing yields, especially varying irrigation research emphasizes critical role factors optimizing production health-benefiting

Language: Английский

---