Trigonelline alkaloid is effective in preventing doxorubicin-induced lung damage

Archives of Physiology and Biochemistry, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 8

Published: Sept. 17, 2024

One of the most popular chemotherapy medications is doxorubicin (DOX), however it can have non-negligible damage. When underlying mechanisms damage are investigated, prominent pathways oxidative stress, inflammation and apoptosis.

Language: Английский

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Discovery and identification of natural alkaloids with potential to impact insulin resistance syndrome in Cyclocarya paliurus. (Batal) leaves by UPLC-QTOF-MS combined with HepG2 cells

Food Research International, Journal Year: 2024, Volume and Issue: 190, P. 114545 - 114545

Published: May 31, 2024

Language: Английский

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The Other Side of the Perfect Cup: Coffee-Derived Non-Polyphenols and Their Roles in Mitigating Factors Affecting the Pathogenesis of Type 2 Diabetes

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(16), P. 8966 - 8966

Published: Aug. 17, 2024

The global prevalence of type 2 diabetes (T2D) is 10.5% among adults in the age range 20–79 years. primary marker T2D persistent fasting hyperglycemia, resulting from insulin resistance and β-cell dysfunction. Multiple factors can promote development T2D, including obesity, inflammation, oxidative stress. In contrast, dietary choices have been shown to prevent onset T2D. Oatmeal, lean proteins, fruits, non-starchy vegetables all reported decrease likelihood onset. One most widely consumed beverages world, coffee, has also demonstrated an impressive ability reduce risk. Coffee contains a diverse array bioactive molecules. antidiabetic effects coffee-derived polyphenols thoroughly described recently reviewed; however, several non-polyphenolic molecules are less prominent but still elicit potent physiological actions. This review summarizes select non-polyphenols on various aspects pathogenesis.

Language: Английский

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Comprehensive investigation of network pharmacology, computational modeling, and pharmacokinetic assessment to evaluate the efficacy of flavonoids in rheumatoid arthritis

Molecular Diversity, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 30, 2024

Language: Английский

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Enhancing the Nutritional and Medicinal Properties of Trigonella persica Seed through Optimized Light Conditions during Germination

Food Bioscience, Journal Year: 2024, Volume and Issue: unknown, P. 105460 - 105460

Published: Nov. 1, 2024

Language: Английский

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