Life, Journal Year: 2025, Volume and Issue: 15(2), P. 221 - 221
Published: Feb. 2, 2025
The genus Ruspolia refers to a small group of plants in the Acanthaceae family, with two dominant species R. decurrens and hypocrateriformis essentially distributed tropical parts Africa. Decoctions from these are used folk medicine for treatment few human pathologies but active ingredients at origin bioactivities have been little studied. Here, we give an insight into main phytochemicals published literature so far their pharmacological properties. flavone glycosides justicialosides A-B likely serve as antioxidant agents free radical scavengers. Several pyrrolidine alkaloids isolated species, notably (nor)ruspolinone related products. These molecules attracted interest medicinal chemists, different synthetic routes leading ruspolinone analogues. There versatile operating procedures synthesize isomers. Despite chemical efforts, pharmacology remains largely unknown. A other isolated, rare bispyrrolidine benzodioxin alkaloid hypercratine, possibly acting ligand β2-adrenergic receptors. phytochemical survey sheds light on diversity products this family promote further investigations mechanism action natural
Language: Английский