The Immunomodulatory Effects of Selenium: A Journey from the Environment to the Human Immune System

Nutrients, Journal Year: 2024, Volume and Issue: 16(19), P. 3324 - 3324

Published: Sept. 30, 2024

Selenium (Se) is an essential nutrient that has gained attention for its impact on the human immune system. The purpose of this review to explore Se’s immunomodulatory properties and make up-to-date information available so novel therapeutic applications may emerge. People acquire Se through dietary ingestion, supplementation, or nanoparticle applications. These forms can beneficially modulate system by enhancing antioxidant activity, optimizing innate response, improving adaptive promoting healthy gut microbiota. Because these many actions, supplementation help prevent treat pathogenic diseases, autoimmune cancers. This will discuss as a key micronutrient with versatile supports disease management due beneficial effects. Further research warranted determine safe dosing guidelines avoid toxicity refine application in medical treatments.

Language: Английский

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S3-Leitlinie Klinische Ernährung bei chronisch-entzündlichen Darmerkrankungen

Aktuelle Ernährungsmedizin, Journal Year: 2025, Volume and Issue: 50(02), P. 80 - 114

Published: April 1, 2025

Zusammenfassung Chronisch-entzündliche Darmerkrankungen (CED) sind nicht nur mit einem erhöhten Risiko für Mangelernährung assoziiert, neuerdings kommt auch Adipositas vor, was die ernährungsmedizinische Begleitbehandlung von Patienten CED verkompliziert. bei erhöht das Komplikationsrisiko, insbesondere chirurgischen Eingriffen, und reduziert möglicherweise Ansprechen auf immunsuppressive Behandlung. Darüber hinaus spielt Ernährung wahrscheinlich der Entstehung eine Rolle, hochverarbeitete Lebensmittel könnten hier Bedeutung sein. Diese andere Aspekte werden in gründlich überarbeiteten Leitlinie „Klinische chronisch-entzündlichen Darmerkrankungen“ 62 evidenz- bzw. expertenbasierten Empfehlungen adressiert. Die basiert früheren DGEM-Leitlinie zum Thema sowie v. a. aktuellen europäischen „ESPEN guideline on Clinical Nutrition inflammatory bowel disease“ 2023. wurde nach „SIGN-Methodik“ erstellt, basierend einer aktualisierten Literaturrecherche Dez. 2021 bis Nov. Erstmals neben oraler Trinknahrung enteraler parenteraler neue „Crohn’s disease exclusion diet“ zur Sprache. macht deutlich, dass fachgerechte Diagnostik, Ernährungstherapie Gewichtskontrolle orale oral/enterale Formulanahrung wichtige Rolle Behandlung spielen. Dadurch können Krankheitsverlauf Lebensqualität verbessert werden.

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Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?

Nutrients, Journal Year: 2025, Volume and Issue: 17(9), P. 1425 - 1425

Published: April 24, 2025

Inflammatory bowel disease (IBDs), including Crohn’s (CD), and ulcerative colitis (UC) are complex diseases with a multifactorial etiology, associated genetic, dietetic, other environmental risk factors. Children IBD at increased for nutritional inadequacies, resulting from decreased oral intake, restrictive dietary patterns, malabsorption, enhanced nutrient loss, surgery, medications. Follow-up of children should routinely include evaluation specific deficits dietetic and/or supplementation strategies be implemented in case deficiencies detected. This narrative review focuses on the prevalence, factors, detection strategy, management micronutrient pediatric IBD.

Language: Английский

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Nutritional Deficiencies and Reduced Bone Mineralization in Ulcerative Colitis

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(9), P. 3202 - 3202

Published: May 6, 2025

Background: Inadequate dietary intake of vitamin D, K, and calcium, as well sub-optimal sunlight exposure, can lead to bone loss in the general population, more so patients with ulcerative colitis, who are burdened by additional predisposing factors for osteoporosis, such chronic inflammation cortisone use. However, micronutrient deficiencies, if present, easily corrected nutritional intervention. While relation between calcium D metabolism is known, fewer data available both healthy individuals patients. The aim this review provide an overview recent reports focusing on deficits relevant development osteoporosis/osteopenia affected colitis. Methods: A systematic electronic search English literature up January 2025 was performed using Medline Cochrane Library. Results: Despite being central mineralization, colitis relatively scarce, deriving mostly from mixed inflammatory bowel disease cohorts. Although lower than controls, approaches recommended daily allowance, which establishes necessary nutrients. Conversely, K deficiencies highly prevalent widely shared opinion that milk lactose-containing foods, vegetables, worsen diarrhea a prime determinant inadequate intake. Conclusions: Increased awareness importance nutrition common occurrence represents first step intervention strategies counteract increased risk osteoporosis

Language: Английский

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Influence of natural polysaccharides on the morphology and properties of hybrid vaterite microcrystals

Heliyon, Journal Year: 2024, Volume and Issue: 10(13), P. e33801 - e33801

Published: June 28, 2024

Language: Английский

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