Unlocking the Potential of Hydrosols: Transforming Essential Oil Byproducts into Valuable Resources DOI Creative Commons
Heloísa H. S. Almeida, Isabel P. Fernandes, Joana S. Amaral

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(19), P. 4660 - 4660

Published: Sept. 30, 2024

The global demand for sustainable and non-toxic alternatives across various industries is driving the exploration of naturally derived solutions. Hydrosols, also known as hydrolates, represent a promising yet underutilised byproduct extraction process essential oils (EOs). These aqueous solutions contain complex mixture EO traces water-soluble compounds exhibit significant biological activity. To fully use these new solutions, it necessary to understand how factors, such distillation time plant-to-water ratio, affect their chemical composition Such insights are crucial standardisation quality control hydrosols. Hydrosols have demonstrated noteworthy properties natural antimicrobials, capable preventing biofilm formation, antioxidants, mitigating oxidative stress. characteristics position hydrosols versatile ingredients applications, including biopesticides, preservatives, food additives, anti-browning agents, pharmaceutical antibiotics, cosmetic bioactives, even anti-tumour agents in medical treatments. Understanding underlying mechanisms activities advancing use. In this context, review compiles analyses current literature on hydrosols’ properties, highlighting potential applications envisioning future research directions. developments consistent with circular bio-based economy, where an industrial from sources repurposed applications.

Language: Английский

Counteracting Skin Aging In Vitro by Phytochemicals DOI Creative Commons
Sara Cruciani, Giuseppe Garroni,

Diletta Serra

et al.

Journal of Cellular and Molecular Medicine, Journal Year: 2025, Volume and Issue: 29(7)

Published: April 1, 2025

ABSTRACT The skin is the most extensive organ in human body. Photo exposure to ultraviolet (UV) rays causes several damages cells, including premature aging, onset of possible DNA mutations, and risk developing cancers, melanoma. Protecting from damaging effects sun through application creams filters important prevent irreversible damages. Several natural extracts biomolecules with antioxidant activity are widely used production dietary supplements or topical products, for prevention treatment affections. Within this context, we pre‐treated fibroblasts (HFF1), skin‐isolated stem cells (SSCs) keratinocytes (HaCaT) two containing a specific solar protection factor (SPF) 72 h then exposed UV light. Gene expression analysis was performed key cell cycle regulators (p16, p19, p21, p53 TERT). Cell senescence assessed by colorimetric assays beta‐galactosidase potential, revealing ability treated counteract free radical as result oxidative stress. Finally, mutations induced photo were studied. results obtained demonstrated that tested products elicit positive on all populations, preserving them senescence, being also able increase repairing mechanisms inducing youngest phenotype.

Language: Английский

Citations

0
Natural Products from the Mediterranean Area as Wound Healing Agents—In Vitro Studies: A Systematic Review DOI Creative Commons

Eleftheria Chorti-Tripsa,

Vasilios Galanis, Theodoros C. Constantinidis

et al.

Antioxidants, Journal Year: 2025, Volume and Issue: 14(4), P. 484 - 484

Published: April 17, 2025

Wound healing is a process that happens when lost tissue replenishes. For this process, both protective elements and wound accelerating factors are required. In recent years, the search for natural products promote faster prevent adverse effects has gained momentum. This systematic review, adhering to PRISMA (Preferred Reporting Items Systematic reviews Meta-Analyses) criteria, of products, with focus on from Mediterranean region. study sourced PubMed Scopus databases eligible articles publications over last six years. Due information volume, only in vitro studies were included review. The criteria set concluded 28 included. These showed many found have been studied treatment wounds. effect seems be related dose, type wounded tissue, application time. Moreover, half additionally tested shown antioxidant activity through DPPH (2,2-diphenyl-1-picrylhydrazyl), ABTS (2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid), FRAP (Ferric Reducing Antioxidant Power) assays.

Language: Английский

Citations

0
Unlocking the Potential of Hydrosols: Transforming Essential Oil Byproducts into Valuable Resources DOI Creative Commons
Heloísa H. S. Almeida, Isabel P. Fernandes, Joana S. Amaral

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(19), P. 4660 - 4660

Published: Sept. 30, 2024

The global demand for sustainable and non-toxic alternatives across various industries is driving the exploration of naturally derived solutions. Hydrosols, also known as hydrolates, represent a promising yet underutilised byproduct extraction process essential oils (EOs). These aqueous solutions contain complex mixture EO traces water-soluble compounds exhibit significant biological activity. To fully use these new solutions, it necessary to understand how factors, such distillation time plant-to-water ratio, affect their chemical composition Such insights are crucial standardisation quality control hydrosols. Hydrosols have demonstrated noteworthy properties natural antimicrobials, capable preventing biofilm formation, antioxidants, mitigating oxidative stress. characteristics position hydrosols versatile ingredients applications, including biopesticides, preservatives, food additives, anti-browning agents, pharmaceutical antibiotics, cosmetic bioactives, even anti-tumour agents in medical treatments. Understanding underlying mechanisms activities advancing use. In this context, review compiles analyses current literature on hydrosols’ properties, highlighting potential applications envisioning future research directions. developments consistent with circular bio-based economy, where an industrial from sources repurposed applications.

Language: Английский

Citations

3