Celal Bayar Üniversitesi Fen Bilimleri Dergisi,
Journal Year:
2024,
Volume and Issue:
20(4), P. 116 - 122
Published: Dec. 9, 2024
Cancer
is
one
of
the
deadliest
diseases
worldwide,
and
for
this
reason,
it
a
prominent
field
study
in
drug
development.
It
has
been
reported
various
studies
that
some
plants
essential
oils
obtained
from
have
high
anticancer
activities.
This
situation
related
to
compound
groups
found
oils.
Studies
on
using
combination
with
synthetic
drugs
or
aromatherapy
are
ongoing.
Essential
show
cytotoxic
properties
may
play
role
death
cancer
cells.
Eugenol
an
important
clove,
laurel,
cinnamon
activity
types
cancer.
ability
reduce
cyclooxygenase-2
(COX-2)
inhibit
cell
proliferation
through
NF-κB
suppression
In
study,
binding
profiles
eugenol
COX-2
Human
inhibitor
nuclear
transcription
factor
κB
(IkB)
kinase
beta,
which
plays
crucial
signaling
pathway,
were
examined
by
molecular
docking
methods
used
computer-aided
design.
A
supporting
was
performed
understand
electrostatic
complementarity
between
ligand
receptor
potential
(MEP)
analysis.
As
result
comparatively
presented
similar
interaction
reference
compounds.
Nutraceuticals,
Journal Year:
2024,
Volume and Issue:
4(4), P. 450 - 468
Published: Sept. 29, 2024
Angiogenesis,
the
process
of
forming
new
blood
vessels
from
existing
ones,
is
crucial
in
both
physiological
and
pathological
conditions,
such
as
tumor
growth,
metastasis,
inflammatory
disorders.
Targeting
angiogenesis
has
emerged
a
promising
therapeutic
strategy.
Recent
research
increasingly
focused
on
role
bioactive
components
found
food
regulating
angiogenesis,
although
there
are
certain
limitations.
This
review
provides
comprehensive
examination
origins,
composition,
pharmacological
activities,
mechanisms
action
these
medicinal
foods,
reflecting
growing
intersection
medicine
nutrition.
The
goal
to
aid
preventing
angiogenesis-related
complications
fostering
healthier
habits.
insights
offered
this
aim
advance
development
effective,
low-toxicity
antiangiogenic
drugs.
Additionally,
been
notable
rise
interest
plant-derived
compounds
with
properties.
investigates
potential
phytoconstituents
plants
drug
candidates
targeting
exploring
their
action,
conducted
thus
far,
challenges
associated
transitioning
into
clinical
applications.
Celal Bayar Üniversitesi Fen Bilimleri Dergisi,
Journal Year:
2024,
Volume and Issue:
20(4), P. 116 - 122
Published: Dec. 9, 2024
Cancer
is
one
of
the
deadliest
diseases
worldwide,
and
for
this
reason,
it
a
prominent
field
study
in
drug
development.
It
has
been
reported
various
studies
that
some
plants
essential
oils
obtained
from
have
high
anticancer
activities.
This
situation
related
to
compound
groups
found
oils.
Studies
on
using
combination
with
synthetic
drugs
or
aromatherapy
are
ongoing.
Essential
show
cytotoxic
properties
may
play
role
death
cancer
cells.
Eugenol
an
important
clove,
laurel,
cinnamon
activity
types
cancer.
ability
reduce
cyclooxygenase-2
(COX-2)
inhibit
cell
proliferation
through
NF-κB
suppression
In
study,
binding
profiles
eugenol
COX-2
Human
inhibitor
nuclear
transcription
factor
κB
(IkB)
kinase
beta,
which
plays
crucial
signaling
pathway,
were
examined
by
molecular
docking
methods
used
computer-aided
design.
A
supporting
was
performed
understand
electrostatic
complementarity
between
ligand
receptor
potential
(MEP)
analysis.
As
result
comparatively
presented
similar
interaction
reference
compounds.
