Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
Language: Английский
Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
Language: Английский
Journal of Materials Chemistry B, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
This review article illustrates and discusses the application of metallic nanomaterials (MNMs) in detection treatment PD, as well theranostic MNMs.
Language: Английский
Citations
0ACS Chemical Neuroscience, Journal Year: 2025, Volume and Issue: unknown
Published: April 3, 2025
Engineered nanoparticles (ENPs) have widely revolutionized many fields, including medicine, technology, environmental science, and industry. However, with the wide use of ENPs in everyday life, concerns are increasingly being raised about their potential neurotoxic effects on central nervous system (CNS), particularly relation to neurodegeneration neuroinflammation. The present systematic review focuses reporting current knowledge ENPs, particular attention mechanism action neuroinflammation neurodegeneration. This PRISMA based encompassed studies from Pubmed, Embase, Web Science. Eligibility criteria included focusing engineered NPs impacts neuroinflammation, neurodegeneration, neurotoxicity. Evidence shows that easily can cross blood-brain barrier (BBB) inducing neuronal damage neurotoxicity due oxidative stress, inflammation, mitochondrial dysfunction, cell death. Inflammation plays a crucial role activating glial cells, such as microglia astrocytes, leading release pro-inflammatory cytokines, chemokines, reactive oxygen species (ROS). increases vulnerability brain systemic inflammation. In conclusion, ENP exposure continues increase, understanding long-term is fundamental developing effective strategies mitigate impact human health.
Language: Английский
Citations
0Food Chemistry, Journal Year: 2024, Volume and Issue: 460, P. 140543 - 140543
Published: July 20, 2024
Language: Английский
Citations
0Advances in medical diagnosis, treatment, and care (AMDTC) book series, Journal Year: 2024, Volume and Issue: unknown, P. 27 - 64
Published: Oct. 11, 2024
Nanomaterials possess different properties that make them suitable for application in numerous fields. Nonetheless, their toxicity, especially neurotoxic propensity, is a considerable area of investigation. In this chapter, nanomaterial neurotoxicity reviewed detail, with an emphasis on assessing levels exposure or routes entry to brain cells, mechanisms by which they cause damage, and specific types damage. addition, vitro, ex vivo, vivo models used measure are described. This chapter provides discussion matter considering challenges terms characterization, risk assessment, regulatory aspects. concludes underscoring the importance toxicological prediction safe-by-design solutions. Future research should address long-term effects using nanomaterials means preventing neurotoxicity.
Language: Английский
Citations
0BioNanoScience, Journal Year: 2024, Volume and Issue: 15(1)
Published: Nov. 28, 2024
Language: Английский
Citations
0Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
Language: Английский
Citations
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