Protective Effects of Alpha-Lipoic Acid and Alagebrium Chloride Against Testicular Dysfunction Induced by Varicocele and Advanced Glycation End (AGE)-Rich Diet in a Rat Mode DOI

S.S. Hosseini,

Marziyeh Tavalaee, Seyed Morteza Seifati

et al.

Tissue and Cell, Journal Year: 2024, Volume and Issue: 90, P. 102509 - 102509

Published: July 31, 2024

Language: Английский

A Comparative Study on the Adverse Effects of a High-Fat Diet on Testicular Tissue: Exploring the Difference Between Obesity-Prone and Obesity-Resistant Mice DOI
Moona Roshanfekr Rad, Mohammad Taghi Sheibani, Mazdak Razi

et al.

Reproductive Sciences, Journal Year: 2025, Volume and Issue: unknown

Published: March 5, 2025

Language: Английский

Citations

0
Androstachys johnsonii Prain aqueous leaf extract attenuates oxidative stress in hyperglycaemic-induced spermatozoa: An in vitro study DOI Creative Commons
Murendeni Nethengwe, Kunle Okaiyeto, Chinyerum S. Opuwari

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: unknown, P. 200204 - 200204

Published: March 1, 2025

Language: Английский

Citations

0
A pathophysiological intersection between metabolic biomarkers and memory: a longitudinal study in the STZ-induced diabetic mouse model DOI Creative Commons

Maria Teresa Venuti,

E. Roda, Federico Brandalise

et al.

Frontiers in Physiology, Journal Year: 2025, Volume and Issue: 16

Published: March 12, 2025

Diabetes mellitus (DM) is a metabolic disorder characterized by high blood sugar levels due to insufficient insulin production or resistance. Recently, biomarkers, such as glycated albumin (GA) and methylglyoxal (MGO), have been successfully employed for the management of diabetes its complications. The main goal this study was investigate relationship between parameters, related diabetic conditions, recognition memory, declarative episodic long-term in streptozotocin (STZ)-induced mouse model. longitudinal experimental plan scheduled five timepoints, starting from 9 months lasting until 19 age, included different evaluations: i) fasting serum glucose, GA, MGO, ii) memory performance; iii) histological examinations pancreas hippocampus. At 13 mice were randomly divided into two groups, STZ (50 mg/kg i.p.) vehicle administered 5 consecutive days. Mice fed with normal diet but, 14 months, half them given water (HS) explore potential detrimental effects HS intake hyperglycemia. Our outcomes are follows: alone does not contribute worsened condition/hyperglycemia; GA emerges reliable biomarker monitoring consistently increasing hyperglycemia; conditions correlate worsening memory; iv) display mild-to-severe insulitis injured hippocampal cytoarchitecture, detectable Ammon’s horns regions CA1 CA3; v) correlation among recovered glycemic level partial regaining physiological pancreatic morphology, cytoarchitecture.

Language: Английский

Citations

0
Cardamonin Attenuates Myocardial Ischemia/Reperfusion-Induced Ferroptosis Through Promoting STAT3 Signaling DOI Creative Commons
Tao Yang,

Pengcui Wu,

Luping Jiang

et al.

Journal of Inflammation Research, Journal Year: 2024, Volume and Issue: Volume 17, P. 8861 - 8879

Published: Nov. 1, 2024

Ferroptosis is intricately associated with the pathophysiology processes of myocardial ischemia. Cardamonin (CAR) has been shown to provide significant protection against tissue damage due multiple ischemia/reperfusion. This study aimed examine cardioprotective properties CAR in ischemia/reperfusion injury (MIRI) and insights into possible mechanisms involved.

Language: Английский

Citations

1
Protective Effects of Alpha-Lipoic Acid and Alagebrium Chloride Against Testicular Dysfunction Induced by Varicocele and Advanced Glycation End (AGE)-Rich Diet in a Rat Mode DOI

S.S. Hosseini,

Marziyeh Tavalaee, Seyed Morteza Seifati

et al.

Tissue and Cell, Journal Year: 2024, Volume and Issue: 90, P. 102509 - 102509

Published: July 31, 2024

Language: Английский

Citations

0