Lung Lesions in Exposure to Pesticides and Herbicides (Literature Review and Case Report) DOI Open Access
И. Т. Муркамилов, К. А. Айтбаев, F. A. Yusupov

et al.

Bulletin of Science and Practice, Journal Year: 2024, Volume and Issue: 10(8), P. 281 - 307

Published: Aug. 14, 2024

Pesticides (herbicides, insecticides, fungicides, zoocides) are mixtures of substances chemical or biological origin used to destroy inhibit the growth microorganisms, fungi, harmful vegetation, and other living organisms. These organisms damage crop livestock production, degrade quality agricultural products, materials, goods. classified into organic, inorganic based on their composition. About 1,000 active ingredients in pesticides, which 310 considered particularly hazardous. Extensive use pesticides leads destruction biocenoses emergence various pathological changes human body. Among pesticide with acute chronic toxicity, abamectin, aluminum phosphide, beta-cyfluthrin, bifenthrin, chlorpyrifos, deltamethrin, diazinon, fenamiphos, malathion, methomyl, oxamyl, primicarb, propargite, tebuconazole, chlorothalonil, bromoxynil, bromoxynil octanoate, brodifacoum, others stand out. In conditions load soils, frequency allergic respiratory diseases is steadily increasing. Chronic obstructive pulmonary disease (COPD), caused by smoking loss working capacity social activity, as well significant costs for treatment rehabilitation. The article discusses pathogenetic clinical aspects formation COPD under synergy (smoking + pesticides). Various phenotypes also considered. A case a patient prolonged contact (mosplan, zellek-super, goal 2E), manifested failure, multifocal atherosclerosis, heart described.

Language: Английский

Pesticide residues in grapes and wine: An overview on detection, health risks, and regulatory challenges DOI

Cleber do Amaral Mafessoni Liviz,

Giselle Maria Maciel,

Débora Fernandes Pinheiro

et al.

Food Research International, Journal Year: 2025, Volume and Issue: 203, P. 115771 - 115771

Published: Jan. 18, 2025

Language: Английский

Citations

0
MWCNT-OH/graphene composite sensor for nonenzymatic detection of paraoxon-ethyl in agricultural samples DOI
Budi Riza Putra,

Elda Nurwidayanti,

Siti Fadilah

et al.

Carbon letters, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 5, 2025

Language: Английский

Citations

0
“Effect of Methoxychlor on Liver Function, Lipid Peroxidation, and Antioxidants in Experimental Rats” DOI Creative Commons

Savina K Ottupurakkal,

E. Jayadevi Variyar, Kunka Mohanram Ramkumar

et al.

Toxicology Reports, Journal Year: 2025, Volume and Issue: 14, P. 101988 - 101988

Published: March 12, 2025

Methoxychlor (MXC), a widely used pesticide, poses significant toxicological risks to various biological systems. It is an environmental contaminant and the only organochlorine pesticide still using instead of DDT. Endocrine disruption MXC also under investigation.This study aimed investigate effects on antioxidant status, lipid peroxidation, liver metabolism in experimental rats. Male Wistar rats were divided into control treatment groups, with latter receiving 150 mg/kg 250 body weight (BW) via oral administration for 30 days. Liver function was assessed by measuring circulating biomarkers, including Alanine Transaminase (ALT), Aspartate (AST), Alkaline Phosphatase (ALP). Oxidative damage evaluated determining Thiobarbituric Acid Reactive Substances (TBARS), hydroperoxide (HYP), other peroxidation markers. Key enzymes involved defense mechanisms analyzed animals. Our results demonstrated increase ALT, AST, ALP levels serum exposed MXC, indicating impaired function. This accompanied elevated further emphasizing oxidative stress. Moreover, activities such as SOD, GPx, CAT markedly reduced MXC-exposed groups compared controls, suggesting compromised system. These findings suggest that methoxychlor exposure disrupts induces stress enhancing thereby depleting natural defenses. highlights potential hepatotoxic underscores role mediating its toxicity.

Language: Английский

Citations

0
Insecticides and testicular health: mechanisms of injury and protective natural products DOI Creative Commons
Samar F. Darwish, Yasser M. Moustafa,

Sherif S Abdel Mageed

et al.

Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2025, Volume and Issue: unknown

Published: March 26, 2025

In agriculture and public health, insecticides are vital chemicals that help manage diseases control pests. However, their extensive use has raised concerns about negative consequences on both humans animals. Pesticide exposure impacts numerous human organs, including the reproductive system. Infertility is caused by system disorders, which why they have received a lot of attention in recent decades. According to what currently known, among substances may lower quality semen produced exposed workers. The mechanisms this action still unclear, even though underlying been suggested. With an emphasis harmful effects male processes, review provides thorough analysis toxicity profile these substances. To reduce insecticides' animal health direct future research initiatives, it essential comprehend consequences.

Language: Английский

Citations

0
Low Ppt Residue Monitoring of Persistent Organic Pollutants in Groundwater Samples Using Direct Immersion Solid Phase Micro Extraction Arrow (Di-Spme) with Gas Chromatography-Mass Spectrometry DOI

Nikolaos Anagnostou,

Kanellos Tountopoulos,

E. De Giorgi

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
Modulating Effects of L-Arginine and Tribulus terrestris Extract on Fipronil-Induced Interference in the Male Reproductive System of Rats: Antioxidant Potential, Androgen Receptors, and Nitric Oxide Synthase Interplay DOI Creative Commons
Doaa H. Elsayed,

Ahmed Bakhashwain,

Eman Ahmed

et al.

Toxics, Journal Year: 2025, Volume and Issue: 13(5), P. 371 - 371

Published: May 2, 2025

The protective potentials of Tribulus terrestris (TT) and L-arginine (L-Arg) against reproductive toxicity induced by fipronil (FPN) in male rats were investigated. A total 36 allocated into six groups: control, TT, L-Arg, FPN, FPN + L-Arg groups. body sex organ weights, semen criteria, serum testosterone levels, testicular oxidative stress determined. Sexual behavior, penile androgen receptor (AR), nitric oxide synthase (NOS), immunohistochemistry proliferating cell nuclear antigen (PCNA), histopathology also assessed. disrupted health influencing the expression activity NOS AR, leading to compromised erectile function, sexual dysfunction, hormonal imbalance. Significant improvements weight, levels observed TT- L-Arg-treated Behavioral assessments indicated improved performance Histopathological studies testes penis tissue, immunohistochemical PCNA tissues, biochemical analyses further confirmed effects TT L-Arg. Collectively, these findings highlighted potential counteracting FPN-induced impairments.

Language: Английский

Citations

0
Exploring Extremotolerant and Extremophilic Microalgae: New Frontiers in Sustainable Biotechnological Applications DOI Creative Commons
Dorian Rojas-Villalta,

David Rojas-Rodríguez,

Melany Villanueva-Ilama

et al.

Biology, Journal Year: 2024, Volume and Issue: 13(9), P. 712 - 712

Published: Sept. 11, 2024

Exploring extremotolerant and extremophilic microalgae opens new frontiers in sustainable biotechnological applications. These microorganisms thrive extreme environments exhibit specialized metabolic pathways, making them valuable for various industries. The study focuses on the ecological adaptation potential of these microalgae, highlighting their ability to produce bioactive compounds under stress conditions. literature reveals that can significantly enhance biomass production, reduce contamination risks large-scale systems, biomolecules such as carotenoids, lipids, proteins. insights suggest have promising applications food, pharmaceutical, cosmetic, biofuel industries, offering efficient alternatives traditional resources. review concludes further exploration utilization unique lead innovative environmentally friendly solutions biotechnology.

Language: Английский

Citations

3
Trends and projections of the burden of disease for male infertility in China from 1990 to 2021: an analysis from the Global Burden of Disease 2021 study DOI Creative Commons
Ran Xu,

Xinjun Wang,

Qiutong Lin

et al.

Frontiers in Reproductive Health, Journal Year: 2024, Volume and Issue: 6

Published: Dec. 16, 2024

Currently, male infertility represents a serious disease burden worldwide, and China is one of the most affected countries. The aim this study was to examine evolution in during period 1990-2021 project trend for 2022-2036.

Language: Английский

Citations

1
Lung Lesions in Exposure to Pesticides and Herbicides (Literature Review and Case Report) DOI Open Access
И. Т. Муркамилов, К. А. Айтбаев, F. A. Yusupov

et al.

Bulletin of Science and Practice, Journal Year: 2024, Volume and Issue: 10(8), P. 281 - 307

Published: Aug. 14, 2024

Pesticides (herbicides, insecticides, fungicides, zoocides) are mixtures of substances chemical or biological origin used to destroy inhibit the growth microorganisms, fungi, harmful vegetation, and other living organisms. These organisms damage crop livestock production, degrade quality agricultural products, materials, goods. classified into organic, inorganic based on their composition. About 1,000 active ingredients in pesticides, which 310 considered particularly hazardous. Extensive use pesticides leads destruction biocenoses emergence various pathological changes human body. Among pesticide with acute chronic toxicity, abamectin, aluminum phosphide, beta-cyfluthrin, bifenthrin, chlorpyrifos, deltamethrin, diazinon, fenamiphos, malathion, methomyl, oxamyl, primicarb, propargite, tebuconazole, chlorothalonil, bromoxynil, bromoxynil octanoate, brodifacoum, others stand out. In conditions load soils, frequency allergic respiratory diseases is steadily increasing. Chronic obstructive pulmonary disease (COPD), caused by smoking loss working capacity social activity, as well significant costs for treatment rehabilitation. The article discusses pathogenetic clinical aspects formation COPD under synergy (smoking + pesticides). Various phenotypes also considered. A case a patient prolonged contact (mosplan, zellek-super, goal 2E), manifested failure, multifocal atherosclerosis, heart described.

Language: Английский

Citations

0