The Role of Platelet Concentrates and Growth Factors in Facial Rejuvenation: A Systematic Review with Case Series

Medicina, Journal Year: 2025, Volume and Issue: 61(1), P. 84 - 84

Published: Jan. 7, 2025

Background and objectives: Due to the regeneration potential of growth factors (GFs) platelet concentrates (PCs), facial rejuvenation has been a major area attention in esthetic medicine. The effectiveness safety PCs GFs promoting face are examined this systematic review, which is complemented by case series. essential for collagen production dermal matrix remodeling, while PCs, like Platelet-Rich Plasma (PRP), abundant bioactive chemicals that promote tissue healing cellular regeneration. Materials Methods: A comprehensive literature search was performed on PubMed, Web Science, Scopus, focusing human clinical trials published between February 2019 2024 related PRP esthetics. Results: Thirteen studies met inclusion criteria were analyzed. Conclusions: review summarizes most recent data patient outcomes, treatment regimens, possible hazards. series goes with it shows real-world examples how improve skin elasticity, texture, general appearance little negative side effects. These results highlight use as minimally invasive procedures.

Language: Английский

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Causal relationship between 14 micronutrients and chronic periodontitis: a Mendelian randomization study

Australian Dental Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 3, 2025

Chronic periodontitis is one of the most common inflammatory diseases worldwide. Micronutrients play a significant impact on health and periodontal disease progression. However, there still lack conclusive studies confirming causal association micronutrients with chronic periodontitis.

Language: Английский

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Evaluating the success rates and effectiveness of surgical and orthodontic interventions for impacted canines: a systematic review of surgical and orthodontic interventions and a case series

BMC Oral Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 24, 2025

Language: Английский

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A Narrative Review of Periodontal Vaccines: Hope or Hype?

Cureus, Journal Year: 2025, Volume and Issue: unknown

Published: March 15, 2025

Globally, periodontal diseases, mainly driven by polymicrobial biofilms, are a widespread concern of social medicine due to their considerable incidence and tie-up systemic disorders like diabetes, cardiovascular complications during pregnancy. Traditional treatments focus on mechanical debridement antimicrobial therapies, but these approaches have limitations, including recurrence antibiotic resistance. Periodontal vaccines offer promising alternative targeting the immunological mechanisms underlying disease. This review explores current state vaccine development, highlighting key antigens, delivery systems, preclinical clinical advancements. Special emphasis is placed antigen selection, host variability, immune tolerance, future directions overcome barriers. article highlights advancements challenges in research, offering insights into capability immunoprophylaxis as groundbreaking way manage diseases.

Language: Английский

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Efficacy of ozone therapy in dentistry with approach of healing, pain management, and therapeutic outcomes: a systematic review of clinical trials

BMC Oral Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 26, 2025

Ozone therapy has emerged as a promising treatment modality in dentistry due to its antimicrobial and healing properties. This systematic review aimed evaluate the recent clinical trials on ozone impact therapeutic outcomes. A comprehensive literature search was conducted across multiple databases, including Web of Science, PubMed, Scopus from January 2018 December 2024, identifying studies that investigated use dental applications. The findings demonstrated is effective improving periodontal health, soft tissue after implant surgery, reducing postoperative discomfort. combination scaling root planing with gaseous showed superior response rates. during endodontics procedures resulted reduced post-treatment pain, while ozonated materials promise management dentinal hypersensitivity. However, it not recommended restorative potential adverse effects bond strength. this supported integration into an adjunctive therapy. More research needed elucidate mechanisms, optimize application techniques, long-term outcomes for patient safety effectiveness.

Language: Английский

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The effect of periodontal treatment on Helicobacter pylori-infection: a systematic review

Deleted Journal, Journal Year: 2025, Volume and Issue: 9(1)

Published: April 10, 2025

Abstract Helicobacter pylori ( H. ), a bacterium widely distributed in the world's population, represents most common cause of chronic gastritis and main risk factor for stomach cancer. The obstacle to eradication is antibiotic resistance, therefore new therapeutic strategies are necessary. Recently, periodontitis has been correlated with several systemic diseases, including -associated gastritis. pathogenetic link between these two diseases inflammation induced by bacteria oral cavity stomach. This systematic review aims evaluate benefits non-surgical periodontal treatment (NSPT) on eradication. PubMed, Scopus, Web Science, Cochrane were searched using MESH terms “Helicobacter pylori” “periodontal treatment”, “periodontal”, “scaling root planning” from January 2015 2025, leading 11 records included final analysis. treatments evaluated studies scaling planing mouthwashing, addition protocols (HPE). A quality assessment risk-of-bias also performed. There evidence that patients infection benefit NSPT. limitations examined small samples, short follow-up, few numbers randomized controlled trials. According our data, NSPT might be HPE guidelines.

Language: Английский

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Personalized Dental Care

IGI Global eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 187 - 210

Published: March 28, 2025

This chapter explores the transformative impact of personalized dental care on modern oral health practices. By moving beyond standardized approaches, dentistry leverages genetic screening, lifestyle analysis, and environmental factors to create tailored treatment plans for patients. The integration markers in risk assessments enables early intervention conditions such as periodontal disease, while patient-specific strategies enhance efficacy compliance. Additionally, advent big data predictive analytics, powered by artificial intelligence, has revolutionized decision-making offering real-time insights precise outcomes. However, also delves into ethical dimensions these advancements, addressing critical issues patient privacy, security, informed consent.

Language: Английский

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Effectiveness of Dental Restorative Materials in the Atraumatic Treatment of Carious Primary Teeth in Pediatric Dentistry: A Systematic Review

Children, Journal Year: 2025, Volume and Issue: 12(4), P. 511 - 511

Published: April 16, 2025

This systematic review evaluates the effectiveness and clinical outcomes of Atraumatic Restorative Treatment (ART) in pediatric dentistry, comparing it with other restorative techniques, analyzing material performance, assessing cost-effectiveness, exploring long-term success managing dental caries. ART is a minimally invasive approach that removes decayed tissue using hand instruments restores teeth adhesive materials like glass ionomer cement (GIC). particularly valuable dentistry due to its simplicity, reduced discomfort, suitability for resource-limited settings. It eliminates need anesthesia expensive equipment, making accessible remote underserved areas. Studies have shown providing durable restorations while improving patient comfort. follows PRISMA guidelines. PubMed, Web Science, Scopus were searched studies published last ten years. The inclusion criteria included vivo on children, randomized controlled trials, case-control ART's effectiveness. Quality risk bias evaluated ROBINS-I tool. Eighteen met criteria. effectively managed caries, especially high-viscosity GIC. Comparisons Hall Technique Papacarie showed remains viable, cost-effective option. reliable, technique dentistry. Its accessibility cost-effectiveness make suitable low-resource High-quality modifications further enhance restoration longevity.

Language: Английский

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Erythropoietin‐Stimulated Macrophage‐Derived Extracellular Vesicles in Chitosan Hydrogel Rescue BMSCs Fate by Targeting EGFR to Alleviate Inflammatory Bone Loss in Periodontitis

Advanced Science, Journal Year: 2025, Volume and Issue: unknown

Published: April 28, 2025

Abstract Loss of periodontal tissue due to persistent inflammation in periodontitis is a major cause tooth loss adults. Overcoming osteogenic inhibition the inflammatory environment and restoring regenerative capacity endogenous bone marrow mesenchymal stem cells (BMSCs) remain critical challenges current treatment approaches. Macrophage‐derived extracellular vesicles (EVs) are key regulators osteogenesis recipient cells, yet role erythropoietin (EPO) modifying macrophages function their EVs regeneration unclear. In this study, from EPO‐stimulated (EPO‐EVs) isolated, they encapsulated chitosan/β‐sodium glycerophosphate/gelatin (CS/β‐GP/gelatin) hydrogel create controlled‐release delivery system for localized environment. EPO‐EVs restore mouse BMSCs (mBMSCs) mitigate model. Mechanistically, miR‐5107‐5p, significantly enriched EPO‐EVs, delivered mBMSCs, where it suppresses epidermal growth factor receptor (EGFR) expression alleviates EGFR's inhibitory effect on RhoA. This process counteracts settings through EGFR/RhoA axis. Overall, EPO pretreated mBMSCs under by inhibiting EGFR expression, providing new insight into therapeutic mechanisms offering promising approach future treatment.

Language: Английский

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Modern methods and technology in periodontal treatment: a review article

International Journal of Community Medicine and Public Health, Journal Year: 2025, Volume and Issue: 12(5), P. 2374 - 2382

Published: April 30, 2025

Periodontal treatment has evolved significantly due to technological advancements and novel methodologies. Between 2020 2024, integrating digital technologies, therapeutic innovations, advanced modalities transformed clinical practice, improving patient outcomes. This review examines recent developments in periodontal care, focusing on methodologies such as laser therapy, guided tissue regeneration (GTR), imaging. Key technologies analyzed include antimicrobial photodynamic therapy (aPDT), cone-beam computed tomography (CBCT), computer-aided design/manufacturing (CAD/CAM), 3D bioprinting. The integration of these enhanced the diagnostic, therapeutic, prognostic capabilities practitioners. Additionally, biomaterials engineering have shown promise regenerative supporting natural healing minimizing invasive surgical interventions. Modern improved efficacy care. highlights evolution techniques, assessing their benefits limitations contemporary practice.

Language: Английский

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