Effect of Stress on Hormone Levels in the Blood Serum of Rats with Alimentary Obesity DOI

Vladimir Vladimirovich Shotaev,

Karina Ruslanovna Doshkhokloeva,

Petimat Hozh-Ahmedovna Vakhidova

et al.

Pharmacophore, Journal Year: 2024, Volume and Issue: 15(3), P. 47 - 52

Published: Jan. 1, 2024

Language: Английский

The impact of oxidative balance on all-cause and cause-specific mortality in US adults and cancer survivors: evidence from NHANES 2001–2018 DOI Creative Commons
Juan Wu, Yingdong Han, Menghui Yao

et al.

BMC Cancer, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 23, 2025

Oxidative stress is a crucial pathophysiological mechanism in chronic diseases and mortality. While individual oxidative markers have been studied, the comprehensive impact of balance on mortality risks remains unclear, particularly among cancer survivors. We aimed to investigate associations Balance Score (OBS) with both general population This study included 37,317 adults (52% female) from National Health Nutrition Examination Survey (2001-2018). OBS was calculated based antioxidant pro-oxidant exposures categorized into quartiles. Survey-weighted Cox proportional hazards models were used estimate hazard ratios for risks. Restricted cubic spline analyses performed examine potential non-linear relationships. Stratified conducted further refine findings. During mean follow-up 9.1 years, 5,092 deaths occurred. Compared lowest quartile, highest quartile total associated lower all-cause (HR 0.68) 0.55). Among survivors, similar observed 0.66). Component analysis revealed consistent protective effects 0.60 mortality), while higher showed varying across causes. Higher risks, cancer-related mortality, effects, varied by

Language: Английский

Citations

1
Comparative Study of Oxidative Stress Responses in Pediatric Type 1 Diabetes and Transient Hyperglycemia DOI Open Access

Anca Daniela Pinzaru,

Ancuţa Ignat, Tatiana Chisnoiu

et al.

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(4), P. 1701 - 1701

Published: Feb. 17, 2025

Hyperglycemia significantly initiates oxidative stress in children diagnosed with type 1 diabetes (T1DM). This study investigates the differences markers between pediatric patients T1DM and those experiencing transient hyperglycemia. In this case-control study, 42 T1DM, according to ISPAD (International Society for Pediatric Adolescent Diabetes), their healthy counterparts, aged 1-6 years old, participated. Blood samples were analyzed biomarkers such as malondialdehyde (MDA) glutathione peroxidase (GPx). There was no statistically significant association found A1c % age, BMI, insulin dose (p > 0.05). A negative correlation Se, Zn, cholesterol, GSH, GPx < 0.05), well a meaningful positive 0.001). GSH exhibited 0.001) diabetic group. comparison control participants, plasma MDA levels (1.3 ± 0.36 µmol/L) had already increased significantly. did correlate group triglyceride 0.0001) or total cholesterol. group, cholesterol normal apparently not influence levels. The state remained unchanged participants temporary hyperglycemia, even though altered link selenium, zinc, lipids.

Language: Английский

Citations

1
The endothelial surface layer-glycocalyx - Universal nano-infrastructure is fundamental to physiology, cell traffic and a complementary neural network DOI Creative Commons
Barry W. Ninham, N. F. Bunkin, Matthew Battye

et al.

Advances in Colloid and Interface Science, Journal Year: 2025, Volume and Issue: 338, P. 103401 - 103401

Published: Jan. 18, 2025

Language: Английский

Citations

0
From planetary health diet (PHD) to mental health: higher PHD index protects against depression among the U.S. population DOI
Cheng Jiang, Seok Choi,

Hongyang Gong

et al.

Journal of Psychiatric Research, Journal Year: 2025, Volume and Issue: 183, P. 31 - 38

Published: Feb. 5, 2025

Language: Английский

Citations

0
Antioxidant Supplementation in Childhood Obesity: A Path to Improved Metabolic Health? DOI Creative Commons
Ancuţa Ignat, Cristina Maria Mihai,

Felicia Dragan

et al.

Antioxidants, Journal Year: 2025, Volume and Issue: 14(4), P. 466 - 466

Published: April 13, 2025

Childhood obesity is linked to heightened oxidative stress, a key driver of endothelial dysfunction, inflammation, and metabolic complications. Antioxidants, including Vitamins C E, are vital in neutralizing free radicals mitigating damage. This non-systematic review examines the potential advantages antioxidant supplementation pediatric obesity, focusing on its effects vascular health, insulin sensitivity, inflammatory processes. Emerging data suggest that antioxidants may improve function, reduce blood pressure, enhance homeostasis obese children. However, long-term efficacy safety remain uncertain, necessitating further rigorous randomized controlled trials. A deeper understanding antioxidants’ role could unlock novel therapeutic approaches for managing obesity-related complications improving children’s overall health outcomes.

Language: Английский

Citations

0
Preparation, Characterization, DFT Calculations, biological evaluations and Molecular docking studies of benzimidazolium-based N-heterocyclic carbenes and selenium-adducts DOI

Areeba Altaf,

Faisal Jamil,

Munazzah Yaqoob

et al.

Inorganica Chimica Acta, Journal Year: 2024, Volume and Issue: 574, P. 122348 - 122348

Published: Aug. 30, 2024

Language: Английский

Citations

2
Effect of Stress on Hormone Levels in the Blood Serum of Rats with Alimentary Obesity DOI

Vladimir Vladimirovich Shotaev,

Karina Ruslanovna Doshkhokloeva,

Petimat Hozh-Ahmedovna Vakhidova

et al.

Pharmacophore, Journal Year: 2024, Volume and Issue: 15(3), P. 47 - 52

Published: Jan. 1, 2024

Language: Английский

Citations

2