Association of systemic inflammatory biomarkers with ocular disease: a large population-based cross-sectional study

European journal of medical research, Journal Year: 2025, Volume and Issue: 30(1)

Published: March 26, 2025

The aim of this study was to explore the association systemic inflammatory biomarkers (systemic immune-inflammation (SII) index and response (SIRI)) with prevalence ocular disease in general population United States (U.S.). We conducted a cross-sectional subjects National Health Nutrition Examination Survey 2005–2008 years. For analysis SII index, SIRI (glaucoma, cataract, age-related macular degeneration (ARMD), diabetic retinopathy), restricted cubic spline (RCS) plot, multivariable logistic regression models, subgroup were performed. There total 5377 individuals. As shown by RCS linked ARMD risk U-shaped pattern. Additionally, linearly positive glaucoma cataract. Finally, retinopathy associated L-shaped N-shaped curves SIRI, respectively. Two new biomarkers, are closely related eye disease. different associations between diseases. This should raise more concerns lead better prevention strategies for inflammation.

Language: Английский

Determinants of retinopathy and short-term neurological outcomes after cerebral malaria

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: April 19, 2025

Language: Английский

Bioinformatics for the Identification of STING-Related Genes in Diabetic Retinopathy

Current Eye Research, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 14

Published: Dec. 20, 2024

Purpose Diabetic retinopathy (DR) is the most common complication of diabetes mellitus. Stimulator interferon genes (STING) plays an important regulatory role in transcription several genes. This study aimed to mine and identify hub relevant STING DR.

Language: Английский