Bone, Journal Year: 2024, Volume and Issue: 192, P. 117363 - 117363
Published: Dec. 3, 2024
Language: Английский
Frontiers in Medicine, Journal Year: 2025, Volume and Issue: 11
Published: Jan. 6, 2025
Mesenchymal stem cells (MSCs) have shown significant potential in bone regeneration and regenerative medicine recent years. With the advancement of tissue engineering, MSCs been increasingly applied repair regeneration, their clinical application has grown through interdisciplinary approaches involving biomaterials genetic engineering. However, there is a lack systematic reviews summarizing applications regeneration. To address this gap, we analyzed latest research on for published from 2013 to 2023. Using Web Science Core Collection, conducted literature search December 2024 employed bibliometric tools like CiteSpace VOSviewer comprehensive analysis key trends. Our findings focus development cell highlighting advantages, limitations, future prospects MSC These insights aim enhance understanding MSC-based inspire new directions, facilitate translation research.
Language: Английский
Citations
3
Journal of Composites Science, Journal Year: 2025, Volume and Issue: 9(3), P. 133 - 133
Published: March 13, 2025
Severe skin injuries such as burns and chronic wounds are a subject of interest in the medical field, they require much attention. These types susceptible to serious complications, which can worsen health patients reduce their quality life. Hydrogels have emerged innovative wound dressings for treating acute wounds, including burns, diabetic foot ulcers, venous leg pressure ulcers. polymeric networks provide moist environment, promote cellular migration, offer antimicrobial properties, being recognized superior conventional dressings. This review aims explore recent advancements hydrogel-based dressings, emphasizing state-of-the-art technologies used this purpose trend achieving personalized therapeutic approaches. Despite promising vitro vivo findings described review, further clinical validation large-scale manufacturing optimizations required widespread adoption.
Language: Английский
Citations
3
Journal of Orthopaedic Translation, Journal Year: 2025, Volume and Issue: 50, P. 129 - 143
Published: Jan. 1, 2025
At present, there is a significant population of individuals experiencing bone deficiencies caused by injuries, ailments affecting the bones, congenital abnormalities, and cancer. The management substantial defects global orthopedic challenge due to intricacies involved in promoting restoring growth fresh osseous tissue. Autografts are widely regarded as "gold standard" for repairing because their superior tissue acceptance ability control osteogenesis. However, patients undergoing autografts may encounter various challenges, including but not limited hernia, bleeding, nerve impairment, death. Therefore, researchers regenerative medicine striving find alternatives. Collagen most abundant protein human body, its triple helix structure gives it unique characteristics that contribute strength functionality tissues. commonly processed into forms such scaffolds, sponges, membranes, hydrogels, composite materials, compatibility with affinity water, minimal potential immune reactions, adaptability, transport nutrients or drugs. As an alternative material field regeneration, collagen becoming increasingly important. objective this review provide comprehensive analysis primary types sources collagen, processes synthesis degradation, well advancements made regeneration research applications. A investigation role undertaken, providing valuable points reference more profound comprehension applications field. concluding section provides overview prospective avenues research, underscoring promising future highlighting regeneration. Translational Potential Article. exploration diverse functions translational demonstrated review, these findings underscore treatment option clinical implications, thus paving way innovative efficacious therapeutic strategies domain.
Language: Английский
Citations
2
Crystals, Journal Year: 2025, Volume and Issue: 15(3), P. 211 - 211
Published: Feb. 23, 2025
Hydrogels represent a versatile class of materials with remarkable potential as three-dimensional matrices for nanoparticle integration. This study explores the mechanism silver formation within polyacrylamide–alginate hybrid hydrogel, employing controlled reduction–oxidation reaction between nitrate (AgNO3) and sodium borohydride (NaBH4) across temperature gradient (5–70 °C). Characterization techniques, including Raman, infrared, UV-Vis spectroscopies, X-ray diffraction, scanning electron microscopy, were employed to analyze structural optical properties nanoparticles hydrogel. The results show that, rose, numbers decreased, while their size increased. Consistently octahedral in shape averaging 100–120 nm, these revealed temperature-dependent growth pattern, rare larger crystals emerging more frequently at higher temperatures. findings highlight hydrogels effective incorporation metal nanoparticles, paving way applications drug delivery, biosensing, antimicrobial treatments.
Language: Английский
Citations
1
Frontiers in Chemistry, Journal Year: 2024, Volume and Issue: 12
Published: Nov. 20, 2024
The extensive utilization of natural polymers in tissue engineering is attributed to their excellent biocompatibility, degradability, and resemblance the extracellular matrix. These have a wide range applications such as delivering therapeutic medicine, detecting diseases, sensing biological substances, promoting regeneration, treating diseases. This brief review current developments properties uses widely used biomedical derived from nature. Additionally, it explores correlation between characteristics functions these materials different highlights prospective direction for advancement polymer engineering.
Language: Английский
Citations
4
Results in Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 102049 - 102049
Published: Jan. 1, 2025
Language: Английский
Citations
0
Advances in Clinical Medicine, Journal Year: 2025, Volume and Issue: 15(01), P. 907 - 914
Published: Jan. 1, 2025
Language: Английский
Citations
0
Colloids and Surfaces B Biointerfaces, Journal Year: 2025, Volume and Issue: 250, P. 114553 - 114553
Published: Feb. 3, 2025
Language: Английский
Citations
0
Materials Chemistry Frontiers, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
This paper summarizes the preparation processes of tailored chitosan-based hydrogels, along with their specific applications in bone regeneration, aiming to inspire innovative designs for hydrogels and foster expanded applications.
Language: Английский
Citations
0
Gels, Journal Year: 2025, Volume and Issue: 11(3), P. 175 - 175
Published: Feb. 27, 2025
Bone tissue engineering has emerged as a promising approach to addressing the limitations of traditional bone grafts for repairing defects. This regenerative medicine strategy leverages biomaterials, growth factors, and cells create favorable environment regeneration, mimicking body’s natural healing process. Among various biomaterials explored, hydrogels (HGs), class three-dimensional, hydrophilic polymer networks, have gained significant attention scaffolds engineering. Thus, this review aimed investigate potential synthetic HGs, molecules used its functionalization, enhanced applications. HGs offer several advantages such scaffolds, including biocompatibility, biodegradability, tunable mechanical properties, ability encapsulate deliver bioactive molecules. These properties make them ideal candidates supporting cell attachment, proliferation, differentiation, ultimately guiding formation new tissue. The design optimization HG-based involve adapting their composition, structure, meet specific requirements regeneration. Current research focuses on incorporating molecules, factors cytokines, into HG further enhance osteoinductive osteoconductive properties. Additionally, strategies improve strength degradation kinetics are being explored ensure long-term stability support formation. development advanced holds great revolutionizing providing effective treatment options patients with
Language: Английский
Citations
0