Relationship between smoking, excessive androgen and negative emotions in women with polycystic ovary syndrome (PCOS) DOI Creative Commons
Yang Yang, Hua Zhang,

Boyun Huang

et al.

Journal of Ovarian Research, Journal Year: 2024, Volume and Issue: 17(1)

Published: Oct. 29, 2024

Lifestyle intervention is the first-line treatment for PCOS. Numerous studies have investigated effect of various lifestyle factors, including dietary habit, smoking, and alcohol consumption on PCOS women. These found that such factors may be associated with physiological parameters as androgen, emotional states like anxiety or depression. Smoking, a harmful habit widely recognized to contribute diseases, has also been related Current research not adequately compared effects smoking other habits PCOS, there little mention its relationship patients To further elucidate association between clinical symptoms in we conducted cross-sectional evaluation using data from Peking University Third Hospital, special focus analyzing comparing it variety factors. This study included 601 women 184 healthy controls who underwent physical examinations, hormone profiles psychological measures. We assessed significant correlation degree depression among three states: anxiety, depression, stress. Smoking was significantly testosterone level participants, suggesting smoke exhibited more severe depressive higher level. In addition, control group, had notably (T) luteinizing (LH) levels. Smoke were statistically common than Control. Women elevated levels findings suggest clinicians should monitor assess their hyperandrogenic status.

Language: Английский

Chemerin and Polycystic Ovary Syndrome: A Comprehensive Review of Its Role as a Biomarker and Therapeutic Target DOI Creative Commons
Stefano Palomba,

Giuseppe Seminara,

Flavia Costanzi

et al.

Biomedicines, Journal Year: 2024, Volume and Issue: 12(12), P. 2859 - 2859

Published: Dec. 16, 2024

Background: Chemerin, an adipokine implicated in inflammatory, metabolic, and adipogenic processes, has been detected high serum concentration women with polycystic ovary syndrome (PCOS) seems to play a role PCOS pathogenesis. Moreover, at present, no comprehensive critical document is available the literature on this topic. The aim of current study was comprehensively review latest data confirm evidence about association between chemerin PCOS, highlighting its potential as upcoming biomarker therapeutic target. Methods: A search studies published 2019 2024 conducted using PubMed, Cochrane Library, Web Science, focusing research related chemerin, PCOS-related features, comorbidities, complications. qualitative structured synthesis key findings performed according specific thematic areas selected, including discussing clinical experimental humans animal models PCOS. Results: Available increased levels compared controls, independent obesity body mass index. Chemerin associated insulin resistance, hyperandrogenism, ovarian dysfunction individuals, inhibiting folliculogenesis steroidogenesis. Experimental underscore chemerin’s regulatory roles through receptors within hypothalamic–pituitary–ovarian axis peripheral tissues. High systemic may also be risk pregnancy complications, especially gestational diabetes mellitus preeclampsia. Conclusions: highlights pathophysiology, severity, comorbidities assessing value future foreshadowing

Language: Английский

Citations

1
Relationship between smoking, excessive androgen and negative emotions in women with polycystic ovary syndrome (PCOS) DOI Creative Commons
Yang Yang, Hua Zhang,

Boyun Huang

et al.

Journal of Ovarian Research, Journal Year: 2024, Volume and Issue: 17(1)

Published: Oct. 29, 2024

Lifestyle intervention is the first-line treatment for PCOS. Numerous studies have investigated effect of various lifestyle factors, including dietary habit, smoking, and alcohol consumption on PCOS women. These found that such factors may be associated with physiological parameters as androgen, emotional states like anxiety or depression. Smoking, a harmful habit widely recognized to contribute diseases, has also been related Current research not adequately compared effects smoking other habits PCOS, there little mention its relationship patients To further elucidate association between clinical symptoms in we conducted cross-sectional evaluation using data from Peking University Third Hospital, special focus analyzing comparing it variety factors. This study included 601 women 184 healthy controls who underwent physical examinations, hormone profiles psychological measures. We assessed significant correlation degree depression among three states: anxiety, depression, stress. Smoking was significantly testosterone level participants, suggesting smoke exhibited more severe depressive higher level. In addition, control group, had notably (T) luteinizing (LH) levels. Smoke were statistically common than Control. Women elevated levels findings suggest clinicians should monitor assess their hyperandrogenic status.

Language: Английский

Citations

0