Sirtuins as Key Regulators in Pancreatic Cancer: Insights into Signaling Mechanisms and Therapeutic Implications DOI Open Access
Surbhi Chouhan, Anil Kumar, Naoshad Muhammad

et al.

Cancers, Journal Year: 2024, Volume and Issue: 16(23), P. 4095 - 4095

Published: Dec. 6, 2024

Pancreatic ductal adenocarcinoma (PDAC) stands as one of the most lethal cancers, marked by rapid progression, pronounced chemoresistance, and a complex network genetic epigenetic dysregulation. Within this challenging context, sirtuins, NAD

Language: Английский

SIRT5-mediated BCAT1 desuccinylation and stabilization leads to ferroptosis insensitivity and promotes cell proliferation in glioma DOI Creative Commons
Tao Wang,

Xin-Hao Han,

Junjun Chen

et al.

Cell Death and Disease, Journal Year: 2025, Volume and Issue: 16(1)

Published: April 7, 2025

Language: Английский

Citations

0
SIRT5 inhibits glycolysis and nasal type extranodal NK/T cell lymphoma cell proliferation by catalyzing the desuccinylation of glucose-6-phosphate isomerase DOI Creative Commons
Tiansheng Wang, Guolin Tan,

Ming Jiang

et al.

Translational Oncology, Journal Year: 2024, Volume and Issue: 51, P. 102215 - 102215

Published: Nov. 29, 2024

Language: Английский

Citations

0
Sirtuins as Key Regulators in Pancreatic Cancer: Insights into Signaling Mechanisms and Therapeutic Implications DOI Open Access
Surbhi Chouhan, Anil Kumar, Naoshad Muhammad

et al.

Cancers, Journal Year: 2024, Volume and Issue: 16(23), P. 4095 - 4095

Published: Dec. 6, 2024

Pancreatic ductal adenocarcinoma (PDAC) stands as one of the most lethal cancers, marked by rapid progression, pronounced chemoresistance, and a complex network genetic epigenetic dysregulation. Within this challenging context, sirtuins, NAD

Language: Английский

Citations

0