Emerging Biomarkers in Early Disease Detection: A Narrative Review DOI
Rahul Chandran

International Journal of Clinicopathological Correlation, Journal Year: 2024, Volume and Issue: 8(2)

Published: Dec. 27, 2024

The early diagnosis of diseases is a fundamental aspect contemporary medicine, crucial for enhancing patient prognosis and alleviating healthcare system burdens. Biomarkers—measurable indicators biological processes or disease states—have emerged as pivotal tools in diagnostics. This review focuses on novel biomarkers detection cancer, cardiovascular diseases, inflammatory conditions, with special emphasis liquid biopsies, circulating tumor DNA (ctDNA), cardiac troponins, cytokines, exosome-based markers. Furthermore, advancements omics technologies artificial intelligence are highlighted transformative this field. Despite their potential, challenges such validation, standardization, practical integration into clinical workflows persist. Addressing these through collaborative research will ensure play central role diagnostics, ultimately advancing global outcomes.

Language: Английский

Bladder cancer biomarkers DOI Creative Commons

Dominik Godlewski,

Dorota Bartusik‐Aebisher,

Sara Czech

et al.

Exploration of Targeted Anti-tumor Therapy, Journal Year: 2025, Volume and Issue: 6

Published: March 25, 2025

Bladder cancer (BCa) is among the most frequently diagnosed urinary tract cancers, characterized by a high recurrence rate and significant clinical heterogeneity. Effective diagnosis treatment of BCa demand continuous advancements in medical technologies, particularly given limitations classical methods such as cystoscopy urine cytology. A comprehensive search PubMed Web Science was conducted using relevant keywords to structure this narrative review. Additionally, specialist journals were reviewed. Only articles English included, with selection based on titles, abstracts, availability full texts. In recent years, biomarkers have emerged crucial tools complementing traditional techniques, providing more precise, sensitive, non-invasive for early detection, prognosis, monitoring response BCa. Molecular, genetic, protein enable deeper understanding biology, creating opportunities personalized therapy tailored individual patient needs. However, despite their potential, certain challenges remain, including standardization, validation, integration into routine practice. This review highlights transformative potential oncological care. It underscores importance incorporating these innovations refine diagnostic therapeutic approaches, ultimately improving outcomes. Modern prognostic can enhance outcomes enabling disease detection reducing risks. progress promises improve patients’ quality life minimizing burden fostering effective, care strategies.

Language: Английский

Citations

0
Spatial metabonomics in immuno-oncology DOI
Delong Zhao, Pengfei Xu

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Language: Английский

Citations

0
Emerging Biomarkers in Early Disease Detection: A Narrative Review DOI
Rahul Chandran

International Journal of Clinicopathological Correlation, Journal Year: 2024, Volume and Issue: 8(2)

Published: Dec. 27, 2024

The early diagnosis of diseases is a fundamental aspect contemporary medicine, crucial for enhancing patient prognosis and alleviating healthcare system burdens. Biomarkers—measurable indicators biological processes or disease states—have emerged as pivotal tools in diagnostics. This review focuses on novel biomarkers detection cancer, cardiovascular diseases, inflammatory conditions, with special emphasis liquid biopsies, circulating tumor DNA (ctDNA), cardiac troponins, cytokines, exosome-based markers. Furthermore, advancements omics technologies artificial intelligence are highlighted transformative this field. Despite their potential, challenges such validation, standardization, practical integration into clinical workflows persist. Addressing these through collaborative research will ensure play central role diagnostics, ultimately advancing global outcomes.

Language: Английский

Citations

0