Syzygium aromaticum extract mediated, sustainable silver nanoparticle synergetic with heterocyclic antibiotic clarithromycin and their antimicrobial activities

Frontiers in Chemistry, Journal Year: 2025, Volume and Issue: 12

Published: Jan. 15, 2025

Microorganisms are becoming resistant to drugs and antimicrobials, making it a significantly critical global issue. Nosocomial infections resulting in alarmingly increasing rates of morbidity mortality. Plant derived compounds hold numerous antimicrobial properties, them very capable source counteract microbial strains. Syzygium aromaticum (Clove) extract has been proven by studies contain active ingredients that demonstrate antibacterial, antifungal, antioxidant, insecticidal properties. It also used historically for its pain relief especially tooth ache. Clove nanoparticle synthesis is promising method combining therapeutics with metals at nanoscale. Such nanostructured systems combination the heterocyclic antibiotic clarithromycin could potentiate action plant extracts, decrease drug side effects improve activity. In this study, clove (C) was successfully synthesize silver nanoparticles (AgNP) create AgNPC AgNPCA (A = clarithromycin). The two underwent different analytical methods consisting SEM, EDS, DLS, UV-vis, FTIR XRD. These were against variety 10 pathogens exhibited good intermediate antibacterial resulted better properties smaller size. This study demonstrates potential mediated AgNP without clarithromycin.

Language: Английский

Preparation, Characterisation, and Photochemical Stability of Polymeric Derivatives of Polyvinyl Alcohol Grafted with Phthalic Anhydride and Dyes

Chemistry Africa, Journal Year: 2025, Volume and Issue: unknown

Published: March 8, 2025

Language: Английский