Genotoxic risks in patients with COVID-19 DOI Creative Commons
Nurşen Başaran, Olga Szewczyk‐Roszczenko, Piotr Roszczenko

et al.

Infection Genetics and Evolution, Journal Year: 2025, Volume and Issue: 129, P. 105728 - 105728

Published: Feb. 13, 2025

The COVID-19 pandemic has caused numerous deaths worldwide. Despite the mitigation of infection manifestations in recent months, possible consequences epidemic remain difficult to predict. Genotoxicity and subsequent development neoplasms are outcomes. This review summarises data on these questions. Studies from several countries have reported increased levels DNA damage nucleated blood cells patients with severe forms infection. level can be used as a prognostic factor for disease outcome. It is considered that SARS-CoV-2 spike proteins play crucial role damage; however, virus also inhibits repair system. Co-morbidities use antiviral drugs may contribute COVID-19.

Language: Английский

Genotoxic risks in patients with COVID-19 DOI Creative Commons
Nurşen Başaran, Olga Szewczyk‐Roszczenko, Piotr Roszczenko

et al.

Infection Genetics and Evolution, Journal Year: 2025, Volume and Issue: 129, P. 105728 - 105728

Published: Feb. 13, 2025

The COVID-19 pandemic has caused numerous deaths worldwide. Despite the mitigation of infection manifestations in recent months, possible consequences epidemic remain difficult to predict. Genotoxicity and subsequent development neoplasms are outcomes. This review summarises data on these questions. Studies from several countries have reported increased levels DNA damage nucleated blood cells patients with severe forms infection. level can be used as a prognostic factor for disease outcome. It is considered that SARS-CoV-2 spike proteins play crucial role damage; however, virus also inhibits repair system. Co-morbidities use antiviral drugs may contribute COVID-19.

Language: Английский

Citations

0