Chitin, Chitosan and Its Derivatives: Antimicrobials and/or Mitigators of Water DOI Creative Commons

Eva Scarcelli,

Alessia Catalano, Domenico Iacopetta

et al.

Macromol—A Journal of Macromolecular Research, Journal Year: 2025, Volume and Issue: 5(2), P. 15 - 15

Published: April 8, 2025

Antimicrobial resistance (AMR) is a major global health problem, exacerbated by the excessive and inappropriate use of antibiotics in human medicine, animal care agriculture. Therefore, new strategies compounds are needed to overcome this issue. In view, it may be appropriate reconsider existing biomaterials alleviate antibiotic overuse. Chitin, naturally abundant amino mucopolysaccharide, poly-β-1, 4-N-acetylglucosamine (GlcNAc). It white, hard, inelastic, nitrogenous polysaccharide source surface pollution coastal areas. Chitosan derives from partial N-deacetylation chitin originates shells crustaceans fungi cell walls. nontoxic natural antimicrobial polymer approved GRAS (Generally Recognized as Safe United States Food Drug Administration). Chitin chitosan, non-toxic biopolymers, useful for wastewater treatment remove pollutants, such pharmaceuticals, heavy metals dyes. The described features make these biopolymers intriguing investigated their application antibacterials.

Language: Английский

Bioactive hydrogel formulations for regeneration of pathological bone defects DOI
Zuhao Li, Kaixuan Ren, Jiajia Chen

et al.

Journal of Controlled Release, Journal Year: 2025, Volume and Issue: 380, P. 686 - 714

Published: Feb. 17, 2025

Language: Английский

Citations

2
Chitosan Approaches in Colon Cancer Therapy: Understanding its Macromolecular Interactions and Structure-Property Relationships DOI
Sankha Bhattacharya, Dilpreet Singh

Journal of Macromolecular Science Part B, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 12

Published: Jan. 9, 2025

Colon cancer is still a significant cause of cancer-related deaths and, therefore, new treatment approaches are required. As naturally derived polysaccharide, Chitosan has become one the most promising materials in polymer-based drug delivery systems because its outstanding biocompatibility, biodegradability, and pH-responsive release. This review explores expanding roles chemical modifications colon therapy, emphasizing relationship between macromolecular interactions structure-property dynamics. Recent progress Chitosan-based nanocarriers, including nanoparticles, nanogels hybrid systems, highlights their potential to overcome multidrug resistance minimize off-target toxicity. These advancements closely aligned with developments precision medicine, incorporating stimuli-responsive components targeted ligands for enhanced efficacy. While preclinical clinical studies yield results, critical challenges such as scalability, reproducibility regulatory compliance remain obstacles translation. emphasizes transformative addressing therapeutic barriers treatment. Looking ahead, future should focus on utilizing cutting-edge technologies, artificial intelligence 3D bioprinting, enhance formulations develop personalized solutions that more effective tailored individual needs.

Language: Английский

Citations

1
Ancient materials for new applications: The combination of montmorillonite with polysaccharides for biomedical uses DOI
Lucilane Gomes Oliveira, Denise B. França, Josy A. Osajima

et al.

Applied Clay Science, Journal Year: 2025, Volume and Issue: 266, P. 107688 - 107688

Published: Jan. 5, 2025

Language: Английский

Citations

0
Chitosan polymer-loaded chemically treated mango (Mangifera indica L.) peel biomass for the adsorption of safranin O dye using Box-Behnken design DOI
Ahmed Saud Abdulhameed, Samaa Abdullah, Alaa A. Al-Masud

et al.

Biomass Conversion and Biorefinery, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 25, 2025

Language: Английский

Citations

0
Hybrid nanocomposite design: exploring the interplay between microstructure, dielectric properties, and photocatalytic activities in Chitosan/Na-Montmorillonite/Fe3O4 nanoparticles DOI

Malek Lahbib,

Chadha Mejri, Mohamed Béjaoui

et al.

Emergent Materials, Journal Year: 2025, Volume and Issue: unknown

Published: March 11, 2025

Language: Английский

Citations

0
The Utilization of Biopolymer Hydrogels to Encapsulate and Protect Probiotics in Foods DOI
Great Iruoghene Edo, Alice Njolke Mafe, Patrick Othuke Akpoghelie

et al.

Process Biochemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

0
Insights into the hybrid coatings derived from stellerite based organic/inorganic composite with synergistic antibacterial activity DOI
Chunquan Li, Yujiao Zhang,

Zengjie Zuo

et al.

Progress in Organic Coatings, Journal Year: 2025, Volume and Issue: 204, P. 109271 - 109271

Published: March 24, 2025

Language: Английский

Citations

0
Chitin, Chitosan and Its Derivatives: Antimicrobials and/or Mitigators of Water DOI Creative Commons

Eva Scarcelli,

Alessia Catalano, Domenico Iacopetta

et al.

Macromol—A Journal of Macromolecular Research, Journal Year: 2025, Volume and Issue: 5(2), P. 15 - 15

Published: April 8, 2025

Antimicrobial resistance (AMR) is a major global health problem, exacerbated by the excessive and inappropriate use of antibiotics in human medicine, animal care agriculture. Therefore, new strategies compounds are needed to overcome this issue. In view, it may be appropriate reconsider existing biomaterials alleviate antibiotic overuse. Chitin, naturally abundant amino mucopolysaccharide, poly-β-1, 4-N-acetylglucosamine (GlcNAc). It white, hard, inelastic, nitrogenous polysaccharide source surface pollution coastal areas. Chitosan derives from partial N-deacetylation chitin originates shells crustaceans fungi cell walls. nontoxic natural antimicrobial polymer approved GRAS (Generally Recognized as Safe United States Food Drug Administration). Chitin chitosan, non-toxic biopolymers, useful for wastewater treatment remove pollutants, such pharmaceuticals, heavy metals dyes. The described features make these biopolymers intriguing investigated their application antibacterials.

Language: Английский

Citations

0