American Journal of Nuclear Medicine and Molecular Imaging, Journal Year: 2024, Volume and Issue: 14(6), P. 371 - 390
Published: Jan. 1, 2024
Language: Английский
American Journal of Nuclear Medicine and Molecular Imaging, Journal Year: 2024, Volume and Issue: 14(6), P. 371 - 390
Published: Jan. 1, 2024
Language: Английский
Cellular Immunology, Journal Year: 2025, Volume and Issue: 409-410, P. 104928 - 104928
Published: Jan. 23, 2025
Language: Английский
Citations
0Quantitative Imaging in Medicine and Surgery, Journal Year: 2025, Volume and Issue: 15(2), P. 1411 - 1424
Published: Jan. 24, 2025
Increased iron accumulation measured by quantitative susceptibility mapping (QSM) has been observed in various brain regions, especially substantia nigra (SN), Parkinson's disease (PD). Glymphatic dysfunction evaluated diffusion tensor image analysis along the perivascular space (DTI-ALPS) PD also attracted much attention recently. This study aimed to compare and combine DTI-ALPS QSM of SN diagnosis severity assessment PD. As a case-control study, we retrospectively recruited 60 patients matched healthy controls. The index, SN, their combination were calculated further compared between two groups. Receiver operating characteristic (ROC) curves used assess diagnostic performance. We analyzed correlation Movement Disorder Society-Unified Disease Rating Scale (MDS-UPDRS) part III score with SN. average was significantly lower, whereas bilateral higher [median (interquartile range): 1.38 (1.26-1.53); 0.09 (0.07-0.10)] controls [1.52 (1.41-1.71), P<0.001; 0.08 (0.07-0.09), P=0.020]. showed area under curve (AUC) 0.801 than that (0.729) or (0.624) discriminating from Moreover, significant correlations MDS-UPDRS (rho =-0.276, P=0.034). are potential biomarkers for them may improve
Language: Английский
Citations
0Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113310 - 113310
Published: March 1, 2025
Language: Английский
Citations
0American Journal of Nuclear Medicine and Molecular Imaging, Journal Year: 2024, Volume and Issue: 14(6), P. 371 - 390
Published: Jan. 1, 2024
Language: Английский
Citations
0