Expression of microRNAs in the Detection and Therapeutic Roles of Viral Infections: Mechanisms and Applications DOI Creative Commons
Mahla Poudineh, Omeed Darweesh, Mehdi Mokhtari

et al.

Journal of Virus Eradication, Journal Year: 2025, Volume and Issue: 11(1), P. 100586 - 100586

Published: March 1, 2025

In recent years, microRNAs (miRNAs) are potential diagnostic and therapeutic agents for viral infections. Here, we aimed to investigate the expression of in identification treatment MiRNAs non-coding molecules that control gene participate numerous biological processes, including host immunity pathogen duplication. have played a role pathogenesis various infections, such as HIV HCV. Their presence tissues serum infected patients has been demonstrated help predict disease progression, identify subtypes, evaluate responses. Research shown miRNAs can detect infections by identifying specific serum. For example, miRNA profiling was recently used distinguish between hepatitis C B precisely. Furthermore, be multiple simultaneously assessing levels these miRNAs. Also, differentiate different genetic variants same virus, which is useful emerging strains or drug-resistant ones. identified being factor treating mimics decreased halted replication HIV, HCV, EBV. Moreover, microRNA antagonists utilized inhibit pro-inflammatory cytokines, thereby modulating immune response severity

Language: Английский

Expression of microRNAs in the Detection and Therapeutic Roles of Viral Infections: Mechanisms and Applications DOI Creative Commons
Mahla Poudineh, Omeed Darweesh, Mehdi Mokhtari

et al.

Journal of Virus Eradication, Journal Year: 2025, Volume and Issue: 11(1), P. 100586 - 100586

Published: March 1, 2025

In recent years, microRNAs (miRNAs) are potential diagnostic and therapeutic agents for viral infections. Here, we aimed to investigate the expression of in identification treatment MiRNAs non-coding molecules that control gene participate numerous biological processes, including host immunity pathogen duplication. have played a role pathogenesis various infections, such as HIV HCV. Their presence tissues serum infected patients has been demonstrated help predict disease progression, identify subtypes, evaluate responses. Research shown miRNAs can detect infections by identifying specific serum. For example, miRNA profiling was recently used distinguish between hepatitis C B precisely. Furthermore, be multiple simultaneously assessing levels these miRNAs. Also, differentiate different genetic variants same virus, which is useful emerging strains or drug-resistant ones. identified being factor treating mimics decreased halted replication HIV, HCV, EBV. Moreover, microRNA antagonists utilized inhibit pro-inflammatory cytokines, thereby modulating immune response severity

Language: Английский

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