Nutrients, Journal Year: 2025, Volume and Issue: 17(8), P. 1339 - 1339

Published: April 14, 2025

Background/Objectives: Type 2 diabetes mellitus (T2DM), is a rapidly growing global health concern, often accompanied by chronic kidney disease (CKD) and metabolic disturbances. Obesity-related indices, such as the visceral adiposity index (VAI) body (BAI), have been linked to cardiovascular renal complications in diabetic patients. However, studies integrating both atherogenic coefficient (AC) prognostic nutritional (PNI) for evaluating nephropathy (DN) remain limited. This study aimed assess associations of obesity-related indices with immunological factors patients T2DM prediabetes (PreDM). Methods: A retrospective, cross-sectional was conducted over six months at university clinical hospital Dolj County, Romania. The enrolled 268 newly diagnosed 150 PreDM Anthropometric parameters, laboratory tests, demographic data were collected. AC PNI calculated using standard formulas, statistical analyses performed determine their inflammatory markers. Results: Our found that had significantly lower values, indicating mild malnutrition, while maintained normal status. higher patients, correlating lipid profile alterations systemic inflammation. Obesity particularly VAI, elevated values. Statistically significant differences total cholesterol, low-density lipoprotein cholesterol (LDL-c), triglycerides observed between subgroups, reinforcing its role risk assessment. Conclusions: findings highlight potential biomarkers assessing nutritional, inflammatory, lipemic status profiles, inflammation markers suggest early assessment these parameters may potentially aid predicting complications. Further are needed explore utility managing CKD progression. Future research should investigate how lipidic spectrum alters progression DN across various patient groups

Language: Английский