Effectiveness of repeated pharmacological courses for patent ductus arteriosus in preterm infants DOI
Carlo Dani,

Giovanni Sassudelli,

Carlotta Milocchi

et al.

Early Human Development, Journal Year: 2024, Volume and Issue: 200, P. 106167 - 106167

Published: Nov. 28, 2024

Language: Английский

Beneficial vs harmful effects of pharmacological treatment of patent ductus arteriosus: A Bayesian meta-analysis DOI
Eduardo Villamor,

Gloria Galán-Henríquez,

František Bartoš

et al.

Pediatric Research, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 15, 2025

Language: Английский

Citations

0

Serum Biomarkers in Patent Ductus Arteriosus in Preterm Infants: A Narrative Review DOI Creative Commons
Manuela Cucerea,

Raluca Marian,

Marta Simon

et al.

Biomedicines, Journal Year: 2025, Volume and Issue: 13(3), P. 670 - 670

Published: March 9, 2025

Background: Patent ductus arteriosus (PDA) in preterm infants presents a significant challenge neonatal care, marked by ongoing debates about its definition, diagnosis, treatment options, and effects on patient outcomes. Plasma biomarkers assess mediators involved PDA closure hemodynamic responses, assisting identifying newborns at higher risk of developing potentially serious conditions. The purpose this review was to investigate the relationship between various plasma used evaluate diagnose ductal patency during perinatal life, as outlined relevant literature. Methods: We conducted an electronic search National Library Medicine (MEDLINE)/PubMed Web Science for studies published up December 2024, including prospective, retrospective, cohort, cross-sectional studies, well reviews meta-analyses. keywords included “preterm infant”, “persistent arteriosus”, “patent “PDA”, “neonatal biomarkers”, “cardiac “vasoactive biomarkers”. Results: Out 813 identified articles, 85 were our cardiac biomarkers: Natriuretic peptides (NPs), Cardiac troponin T (cTnT), vasoactive (Mid-regional pro-adrenomedullin (MR-proADM), Endothelin-1 (ET-1), Copeptin, Isoprostanes (IPs)), inflammatory (Interleukin-6 (IL-6), IL-8, IL-10, Growth Differentiation Factor 15 (GDF-15), Monocyte Chemoattractant Protein-1 (MCP-1/CCL2), Macrophage Inflammatory Protein-1α (MIP-1α/CCL3)) relation PDA. Conclusions: Even if research shows strong correlation specific echocardiographic parameters patients with PDA, clinical judgment must take these evaluations into account, particularly when determining whether treat Future should focus investigating new associated underlying mechanisms dynamics infants.

Language: Английский

Citations

0

Längere Persistenz eines offenen Ductus arteriosus führt nicht zu einer Verschlechterung des neurologischen Outcome DOI

M Kallenberger,

Britta Hüning,

Johanna Bialas

et al.

Zeitschrift für Geburtshilfe und Neonatologie, Journal Year: 2025, Volume and Issue: 229(03), P. e86 - e87

Published: May 1, 2025

Citations

0

Procedural closure of the patent ductus arteriosus in preterm infants: a clinical practice guideline DOI
Souvik Mitra, Adrianne Rahde Bischoff, Shyam Sathanandam

et al.

Journal of Perinatology, Journal Year: 2024, Volume and Issue: 44(10), P. 1402 - 1408

Published: July 12, 2024

Language: Английский

Citations

3

Who Still Gets Ligated? Reasons for Persistence of Surgical Ligation of the Patent Ductus Arteriosus Following Availability of Transcatheter Device Occlusion for Premature Neonates DOI Creative Commons
J Hoffmann, Zahra Khazal,

Wievineke Apers

et al.

Journal of Cardiovascular Development and Disease, Journal Year: 2024, Volume and Issue: 11(5), P. 132 - 132

Published: April 23, 2024

(1) Background: To identify reasons for the persistence of surgical ligation patent ductus arteriosus (PDA) in premature infants after 2019 Food and Drug Administration (FDA) approval transcatheter device closure; (2) Methods: We performed a 10-year (2014–2023) single-institution retrospective study (<37 weeks) compared clinical characteristics neonatal morbidities between neonates that underwent before (epoch 1) 2) FDA (3) Results: identified 120 (n = 94 before, n 26 approval). Unfavorable PDA morphology, active infection, recent abdominal pathology were most common over occlusion epoch 2. There no differences demographics, age at closure, or outcomes who received two epochs; (4) Conclusions: Despite increasing trends closure infants, persists due to unfavorable ductal pathology.

Language: Английский

Citations

1

Genetic Foundation of Prostaglandin Metabolism Influences Patent Ductus Arteriosus Closure in Extremely Low Birth Weight Infants DOI
Hannah J. Sampath, Parvathy Krishnan,

Van Trinh

et al.

American Journal of Perinatology, Journal Year: 2024, Volume and Issue: 42(01), P. 043 - 051

Published: May 31, 2024

Prostaglandins (PGs) play a major role in maintaining patency of the ductal arteriosus (DA). Pulmonary 15-hydroxyprostaglandin dehydrogenase (PGDH), which is ecoded by hydroxyprostaglandin (

Language: Английский

Citations

0

Effectiveness of repeated pharmacological courses for patent ductus arteriosus in preterm infants DOI
Carlo Dani,

Giovanni Sassudelli,

Carlotta Milocchi

et al.

Early Human Development, Journal Year: 2024, Volume and Issue: 200, P. 106167 - 106167

Published: Nov. 28, 2024

Language: Английский

Citations

0