Towards Automatic Assessment of Atypical Early Motor Development?

Brain Research Bulletin, Journal Year: 2025, Volume and Issue: unknown, P. 111311 - 111311

Published: March 1, 2025

Atypical motor development is an early indicator for several neurodevelopmental conditions, including cerebral palsy and Rett Syndrome, prompting diagnosis intervention. While not currently part of the diagnostic criteria other conditions like Autism Spectrum Disorder, frequent retrospective impairments alongside these highlights necessity a deeper understanding relationship between cognitive development. Traditional clinical assessments, while considered gold standard, rely on movement characteristics discernible to trained eye professionals. The emergence automated technologies, computer-vision wearable sensors, promises more objective scalable detections. However, methods are without challenges, concerns over data quality, generalizability, interpretability, ethics. By reviewing recent advances, we highlight potential challenges integrating detections into research practice. agree that technologies can revolutionize pediatric care, believe their use must be tempered with caution supported by expertise ensure effective outcomes.

Language: Английский

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Neurodevelopmental screening for neonates less than 44 weeks gestation in low-income and middle-income countries: a systematic review

BMJ Global Health, Journal Year: 2025, Volume and Issue: 10(4), P. e017683 - e017683

Published: April 1, 2025

Introduction With global improvements in neonatal survival, more small and sick newborns low-income middle-income countries (LMICs) are at increased risk of neurodevelopmental disability delay. While there is recognition the importance early identification differences timely initiation therapy, little known about standardised screening tools these settings. Methods We performed a systematic review to determine what assessments had been used LMICs for neonates before 44 weeks corrected gestational age published literature. excluded short-term clinical designed specific pathologies. search across seven databases, screened studies eligibility inclusion extracted bibliographic data, country, patient characteristics, study aims. Results were summarised tabular graphical presentation. There 2477 records screened, yielding 67 inclusion. Studies Asian made up 65.7%, while Latin America Africa 19.4% 16.4%, respectively. Physicians paramedical staff only 16.4% studies, 92.5% inpatient recruitment. The Neonatal Behavioural Neurological Assessment (25.4%) was most frequently tool followed by General Movements (22.4%), Hammersmith Examination/Dubowitz (16.4%) Scale (10.4%). Conclusions did not identify any one assessment that rapid, globally validated, identifies targets intervention, has high predictive prognostic value does require or kinesiologic expertise uncommon equipment. Such an assessment, concert with evidence-based therapeutic delivery platforms, established referral pathways trained personnel would improve functional outcomes high-risk LMICs.

Language: Английский

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Introductory Chapter: Advances in Prenatal and Neonatal Diagnostics

IntechOpen eBooks, Journal Year: 2025, Volume and Issue: unknown

Published: April 10, 2025

Language: Английский

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Impact of respiratory viral infections during pregnancy on the neurological outcomes of the newborn: current knowledge

Frontiers in Neuroscience, Journal Year: 2024, Volume and Issue: 17

Published: Jan. 8, 2024

Brain development is a complex process that begins during pregnancy, and the events occurring this sensitive period can affect offspring's neurodevelopmental outcomes. Respiratory viral infections are frequently reported in pregnant women, and, last few decades, they have been related to numerous neuropsychiatric sequelae. viruses disrupt brain by directly invading fetal circulation through vertical transmission or inducing neuroinflammation maternal immune activation production of inflammatory cytokines. Influenza virus gestational infection has consistently associated with psychotic disorders, such as schizophrenia autism spectrum disorder, while recent pandemic raised some concerns regarding effects severe acute respiratory syndrome coronavirus 2 on outcomes children born affected mothers. In addition, emerging evidence supports possible role syncytial risk factor for adverse consequences. Understanding mechanisms underlying developmental dysfunction allows improving preventive strategies, early diagnosis, prompt interventions.

Language: Английский

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Abnormal Neurologic and Motor Function in Newborns Treated for Congenital Syphilis

Infectious Disease Reports, Journal Year: 2025, Volume and Issue: 17(2), P. 34 - 34

Published: April 16, 2025

Background: Congenital syphilis (CS) is a transplacental infection that can lead to many long-term sequelae when not adequately treated; however, knowledge about the motor and neurological signs newborns (NBs) with CS may present scarce. Objective: The aim of this study was describe results assessment scales general movements in NBs first days life. Methods: In case-series, Hammersmith Neonatal Neurological Examination (HNNE) General Movements Assessment (GMA) were used evaluate under treatment for public Brazilian hospital Results: sample consisted 11 NBs, mean birth weight 3140.5 g, an Apgar score at 5 min 8.3. Among mothers, 4 (36.4%) had fewer than six prenatal visits (45.5%) did receive any treatment. All NB (100%) asymptomatic, normal long bone X-rays cerebrospinal fluid analysis. on HNNE 22 (suboptimal/abnormal). Eight (72.7%) showed abnormalities GMA scale (with [54.5%] being mildly abnormal two [18%] definitely abnormal). Only three (27.3%) returned outpatient follow-up. Conclusions: evaluations most asymptomatic life, assessed through specific (HNNE GMA). Most mothers adequate during pregnancy, there important deficiencies post-discharge Further studies are needed confirm these findings investigate whether observed linked biological or environmental factors pregnancy.

Language: Английский

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