Long COVID neuropsychological follow-up: Is cognitive rehabilitation relevant?

Neurorehabilitation, Journal Year: 2023, Volume and Issue: 53(4), P. 517 - 534

Published: Dec. 19, 2023

BACKGROUND: Duration of neuropsychological disorders caused by long COVID, and the variables that impact outcomes, are still largely unknown. OBJECTIVE: To describe cognitive profile patients with COVID post-participation in a rehabilitation program subsequent reassessment identify factors influence recovery. METHODS: 208 (mean age 48.8 y.o.), mostly female, were reevaluated 25 months after their first infection 17 initial evaluation. Patients underwent subjective assessment, Barrow Neurological Institute Screen for Higher Cerebral Functions (BNIS), Phonemic Verbal Fluency Clock Drawing Tests (NEUPSILIN) executive functions, Hospital Anxiety Depression Scale (HADS) WHOQol-Bref. RESULTS: We noted discrete improvement symptoms acute stage COVID-19; nonetheless, performance was not within normative parameters standardized testing. These results negatively QoL corroborate patients’ assessments issues experienced daily life. Improvement seen those who participated psychoeducational rehabilitation, had higher levels education, lower depression scores on HADS. CONCLUSION: Our data reveal persistence long-term neuropsychiatric COVID. Neuropsychological is shown to be important, whether in-person or online.

Language: Английский

---

Factors associated with prolonged COVID-related PTSD-like symptoms among adults diagnosed with mild COVID-19 in Poland

Frontiers in Psychology, Journal Year: 2024, Volume and Issue: 15

Published: March 14, 2024

COVID-19 has been considered a possible cause of post-traumatic stress disorder (PTSD) or similar conditions. However, what specific disease symptoms may contribute most to prolonged PTSD-like in survivors is unclear. The study aimed present the factor structure and identify which best explain subsequent presence mild survivors. COVID-positive adults ( n = 341) completed online self-report scales at baseline assessment (T1) after approximately 4 months (T2), including Patient Health Questionnaire Anxiety-Depression Scale; Scale Psychosocial Experience Related COVID-19, Primary Care PTSD Screen for DSM-5; self-designed questionnaires evaluating severity COVID-related medical neurocognitive pre-pandemic variables. Exploratory analysis revealed five factors symptoms: flu-like, respiratory, cold, neurological, neurocognitive. Hierarchical logistic regression showed that besides selected control variables (anxiety depression, symptoms, stigma T1), T1 but not other were significant predictor symptom T2. Findings suggest need comprehensive people diagnosed with prompt interventions targeting prevention potential risks long-term states community level.

Language: Английский

---

Could We Designate Long COVID a Syndrome?

Science Insights, Journal Year: 2024, Volume and Issue: 44(6), P. 1389 - 1391

Published: June 29, 2024

Long COVID has been subject to growing examination as researchers and healthcare professionals strive gain a deeper comprehension of its fundamental mechanisms consequences. While syndromes often consist group symptoms without distinct underlying cause, seems be more intricate. Studies indicate that it could affect several organ systems cause cellular-level harm, prompting specialists propose categorized syndrome rather than simple lingering consequences the virus. However, further study needs conducted for determining whether there are distinctive characteristics differentiate clinical entity from other post-viral conditions. Accurate identification will essential in guiding treatment approaches delivering appropriate therapy patients who suffer persistent after being infected with COVID-19.

Language: Английский

---

Compassion Fatigue in a Cohort of South Italian Nurses and Hospital-Based Clinical Social Workers Following COVID-19: A Cross-Sectional Survey

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(14), P. 4200 - 4200

Published: July 18, 2024

Background/Objective: The COVID-19 pandemic has led to a significant increase in the workloads of healthcare workers (HCWs). fear contracting new virus with frequent medical consequences affected their mental health. As result, they are at high risk compassion fatigue (CF). In this multicentric study, as primary objective, we evaluate incidence and/or prevalence CF cohort Italian nurses and HCWs (hospital-based clinical social neurological patients) who have contracted SARS-CoV-2 infection. Our secondary aim is difference experiencing between subjects without long-term COVID. Methods: 101 attending three different neurorehabilitation settings (the Neurorehabilitation Unit “Bonino Pulejo” Neurolesi Center Messina, Department Crotone, Psychiatric University Hospital Messina) were enrolled from May 2021 2023. Data collected through self-administered semi-structured interviews. Results: We observed percentages difficulties both HCWs, related mood alteration 57.7%, headaches 44.4%, 62%. Higher found individuals COVID-19, including 93.9%, headache 88.6%, memory-related problems 98.5%. Conclusions: complexity patient’s care pathway, especially chronic disease situations, requires an enormous commitment that can lead burnout CF, which should be considered initiate preventive interventions aimed helping “those help”, for well-being patients, teams, organizations.

Language: Английский

---

Utility of teleneuropsychology services among pediatric patients with long COVID

The Clinical Neuropsychologist, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 15

Published: Dec. 26, 2024

Objective: To determine the clinical utility of teleneuropsychology (teleNP) services in screening for cognitive concerns a population children and adolescents presenting with long COVID. Method: This cross-sectional study evaluated 76 pediatric patients (64% female, Mage = 13.48, SD 2.97, range 5 to 18 years) COVID referred neuropsychological evaluation due persistent symptoms following their infection. Of these patients, 33 were tested person, while 43 via teleNP at home. Patients administered brief testing battery designed use in-person or through services. Tests included WASI-II (Intellectual Functioning), D-KEFS Verbal Fluency (Executive Functioning/Shifting), Oral Version Symbol Digit Modalities Test (Processing Speed), ChAMP List (Learning Memory), WAIS-IV/WISC-V Span (Working TEA-Ch Score DT (Sustained Auditory Attention Divided Attention). Differences scores between those computed using analyses variance Bayesian statistics across measures. proportion scoring below average (< 9th percentile) also computed. Results: Findings revealed similar performance by modality Conclusions: The present provides preliminary evidence on battery. These results lend support expanding assess neurocognitive functioning, which is particularly important given scarcity specialty clinics.

Language: Английский

---

Greater Role of Cognitive Impairment Over Fatigue in Post-COVID-19 Quality of Life: A Post-Hoc Analysis of a Randomized Controlled Trial

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: March 22, 2024

ABSTRACT Background Post COVID-19 Condition (PCC) is a common and debilitating condition with significant reports of fatigue psychosocial impairment globally. The extent to which cognitive symptoms contribute reduced quality life in affected individuals remains clear. Methods This post-hoc analysis randomized, double-blind, placebo-controlled clinical trial that evaluated the effect vortioxetine on function adults PCC. herein aimed determine overall baseline [as measured by Digit Symbol Substitution Test (DSST)] severity Fatigue Severity Scale (FSS)] health-related (HRQoL) 5-item World Health Organisation Well-Being Index (WHO-5)]. Results A total 200 participants were enrolled primary trial. Due missing data, our statistical included measures 147 individuals. Our generalized linear model revealed positive correlation between DSST-measured objective self-reported WHO-5-measured HRQoL (β = 0.069, 95% CI [0.006, 0.131], p 0.032). In contrast, negative FSS WHO-5 scores -0.016, [-0.021, –0.011], < 0.001). beta-coefficient ratio DSST / β 0.069 0.016) calculated as 4.313. Conclusions Overall, we observed increased was associated at Moreover, decreased Furthermore, an improvement would have four-fold greater impact than generated fatigue.

Language: Английский

---

A Step Forward in Long COVID Research: Validating the Post-COVID Cognitive Impairment Scale

European Journal of Investigation in Health Psychology and Education, Journal Year: 2024, Volume and Issue: 14(12), P. 3001 - 3018

Published: Dec. 1, 2024

Long COVID, or post-acute sequelae of SARS-CoV-2 infection, includes a variety enduring symptoms that endure beyond the acute phase illness, impacting multiple facets patients’ psychological and physical health. The persistent encompass fatigue, breathing difficulties, musculoskeletal pain, cognitive impairments, which can significantly affect daily functioning overall quality life. objective this study was to create validate accuracy Post-COVID Cognitive Impairment Scale, is used evaluate impairments resulting from COVID-19 infection. This conducted in Iran between January September 2023. It consisted three phases: developing scale, evaluating its content validity with experts, validating structure 454 participants using exploratory confirmatory factor analysis. analysis revealed two variables, namely memory attention, accounted for 40.38% variation. Confirmatory verified model’s fit, indices indicating satisfactory alignment: CMIN/DF = 2.80, RMSEA 0.06, SRMR 0.05, CFI 0.93, TLI 0.92. loadings were statistically significant (p < 0.001), Cronbach’s Alpha values indicated strong internal consistency (working 0.81, attention 0.80). These results affirm Scale valid reliable instrument deficiencies individuals long COVID. Its application clinical research environments aids prompt detection tracking treatment such impairments.

Language: Английский

---

Anti-SARS-CoV-2 IgG Antibody Response in Individuals Infected Post Complete Vaccination: A 6-Month Longitudinal Study in Healthcare Professionals

Vaccines, Journal Year: 2023, Volume and Issue: 11(6), P. 1077 - 1077

Published: June 8, 2023

Serological assays have been used to evaluate the magnitude of naturally acquired and BNT162b2 vaccine-induced immunity. In order assess extent which antibody response correlates with infection-mediated protection after vaccination, we investigated kinetics anti-SARS-CoV-2-S1 IgG in fully vaccinated healthy individuals who did or not develop COVID-19 within 8 months booster dose. The receptor-binding, domain-specific titer was assessed serum samples collected at various intervals from 4 second 6 third level decreased 33% dose and, one month dose, increased dramatically (>300%) compared pre-booster time point. infection two cause significant variation, but later viral infections elicited an similar initial booster. probability developing severity symptoms were related titer. Our data indicate that repeated exposure antigens by either vaccination short-term elicits limited boosting effects alone is associated prediction future their symptomatology.

Language: Английский

---

The Role of Movement, Exercise, and Breathing in the Prevention and Treatment of COVID-19: An Umbrella Review

CAND Journal, Journal Year: 2023, Volume and Issue: 30(4), P. 32 - 42

Published: Dec. 28, 2023

Objective: To identify the published review literature regarding movement, exercise, and breathing in prevention and/ or treatment of coronavirus 2019 disease (COVID-19) long COVID, with goal describing identifying areas for further research clinical application. Movement exercise incorporate sedentary behaviours, various forms respiratory therapies, yoga-asanas (postures). Methods: This paper progresses from a live incorporates systematic reviews narrative reviews. A search occurred monthly using PubMed Google Scholar May 2022 to 2023. measurement tool assess (AMSTAR) scoring assessed quality, while scale assessment articles (SANRA) guidelines were used evaluate Only information data focused on movement relevant COVID-19 and/or extracted each review. Results: Three five included. Sedentary behaviours increased significantly during pandemic. Decreased physical activity level was associated risk hospitalization COVID-19. Physical exercises, whether conducted face-to-face (F-2-F) via telerehabilitation improvement dyspnea (shortness breath), capacity, lung function, fatigue, quality life (QoL). Extreme is best avoided at least 2 3 weeks after severe symptoms. Conclusion: behaviour lack regular correlated an Various may be beneficial COVID. Further understanding importance as it relates immune health warranted.

Language: Английский

---

Mapping of long COVID conditions in India: A study protocol for systematic review and meta-analysis

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 19, 2024

Abstract The COVID-19 pandemic has posed significant concern revolves around the prolonged effects experienced by a subset of individuals post-acute sequelae SARS- COV-2 infection, termed long COVID. This study protocol outlines methodology for meta-analysis and systematic review with objective comprehensively assessing on Indian population determine likely risk factors connected to development persistence A comprehensive search strategy will be employed across major databases. By combining data from various studies, expected outcomes include clearer understanding documentation long-term prevalence rates COVID, symptom profiles, regional disparities, potential determinants COVID conditions within population. anticipated findings contribute refined this condition, guiding healthcare interventions future research endeavors aimed at mitigating impact condition

Language: Английский

---