Time Trend Analysis of Comorbidities in Ankylosing Spondylitis: A Population-Based Study from 53,142 Hospitalizations in Poland DOI Open Access

Katarzyna Helon,

Małgorzata Wisłowska,

Krzysztof Kanecki

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(2), P. 602 - 602

Published: Jan. 21, 2024

Background: (1) Influence of comorbidities on life expectancy and treatment outcomes is one the main concerns modern rheumatology, due to their rising prevalence increasing impact mortality disability. The objective our study was analyze time trends shifts in comorbidity profile over 10 years Polish population with ankylosing spondylitis (AS). (2) Data from 2011–2020 were acquired General Hospital Morbidity Study National Institute Public Health—National Hygiene (NIH-PIB) as ICD-10 codes. Based ICD10 codes, we calculated percentage shares for comorbidities, relative risk ratios odds ratios. We analyzed hospitalization rates overlapping conditions. Also, age sex related differences clinical manifestations AS patients. (3) Results: From 53,142 hospitalizations patients AS, found that male presented higher cardiovascular (2.7% vs. 1.3% p < 0.001) pulmonary conditions (1.2% 0.8% 0.025). Inflammatory bowel diseases more common female than males (2.3% 1.7%, 0.001). In 2011–2020, observed a decline number hospitalized (p respiratory system 0.001), yet odd remained high. 4056 received biological (7%). initiated therapies correlated negatively reported ischemic heart (IHD) 0.031, r = −0.8). Furthermore, logistic regression model, strong collinearity between (VIF 14; tolerance 0.1); also, IHD’s positively infections 0.7) (4). Conclusions: Cardiopulmonary are factor associated increased especially among admitted hospital other movement disorders exceed populational risk. biologically treated admissions IHD.

Language: Английский

Time Trend Analysis of Comorbidities in Ankylosing Spondylitis: A Population-Based Study from 53,142 Hospitalizations in Poland DOI Open Access

Katarzyna Helon,

Małgorzata Wisłowska,

Krzysztof Kanecki

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(2), P. 602 - 602

Published: Jan. 21, 2024

Background: (1) Influence of comorbidities on life expectancy and treatment outcomes is one the main concerns modern rheumatology, due to their rising prevalence increasing impact mortality disability. The objective our study was analyze time trends shifts in comorbidity profile over 10 years Polish population with ankylosing spondylitis (AS). (2) Data from 2011–2020 were acquired General Hospital Morbidity Study National Institute Public Health—National Hygiene (NIH-PIB) as ICD-10 codes. Based ICD10 codes, we calculated percentage shares for comorbidities, relative risk ratios odds ratios. We analyzed hospitalization rates overlapping conditions. Also, age sex related differences clinical manifestations AS patients. (3) Results: From 53,142 hospitalizations patients AS, found that male presented higher cardiovascular (2.7% vs. 1.3% p < 0.001) pulmonary conditions (1.2% 0.8% 0.025). Inflammatory bowel diseases more common female than males (2.3% 1.7%, 0.001). In 2011–2020, observed a decline number hospitalized (p respiratory system 0.001), yet odd remained high. 4056 received biological (7%). initiated therapies correlated negatively reported ischemic heart (IHD) 0.031, r = −0.8). Furthermore, logistic regression model, strong collinearity between (VIF 14; tolerance 0.1); also, IHD’s positively infections 0.7) (4). Conclusions: Cardiopulmonary are factor associated increased especially among admitted hospital other movement disorders exceed populational risk. biologically treated admissions IHD.

Language: Английский

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