The role of radiomics in computed tomography, magnetic resonance imaging, and ultrasound for renal tumors’ diagnoses: A systematic review DOI Creative Commons

Zenghui Xi,

Jing Li, Xue Liu

et al.

Journal of Radiation Research and Applied Sciences, Journal Year: 2023, Volume and Issue: 17(1), P. 100769 - 100769

Published: Dec. 1, 2023

Radiomics is a collection of data and features obtained from medical imaging techniques. In this systematic review, various databases were comprehensively searched to understand the diagnostic role radiomics in computed tomography (CT), magnetic resonance (MRI), ultrasound (US) renal tumors. All original human studies evaluating diagnosis tumors that used CT, MRI, or US included. The findings showed many have been conducted on methods for detection benign malignant demonstrated higher sensitivity specificity compared CT MRI. It crucial conduct machine learning incorporating MR techniques more comprehensive comparisons.

Language: Английский

Comparative Diagnostic Performance of Color Doppler Flow Imaging, MicroFlow Imaging and Contrast-enhanced Ultrasound in Solid Renal Tumors DOI
Chunxiang Li,

Lisha Qi,

Changming Geng

et al.

Academic Radiology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

1
Diagnostic Accuracy of Contrast-Enhanced Ultrasound (CEUS) in the Detection of Muscle-Invasive Bladder Cancer: A Systematic Review and Diagnostic Meta-Analysis DOI Creative Commons
Antonio Tufano, Davide Rosati, Martina Moriconi

et al.

Current Oncology, Journal Year: 2024, Volume and Issue: 31(2), P. 818 - 827

Published: Feb. 1, 2024

Background: Contrast-enhanced ultrasound (CEUS) is a diagnostic tool that gaining popularity for its ability to improve overall accuracy in bladder cancer (BC) staging. Our aim determine the cumulative performance of CEUS predicting preoperative muscle invasiveness using comprehensive systematic review and pooled meta-analysis. Methods: A until October 2023 was performed according Preferred Reporting Items Systematic Reviews Meta-Analyses (PRISMA) statement. Patients with BC suspicion were offered before transurethral resection tumor (TURBT). The evaluated based on non-muscle-invasive (NMIBC) vs. muscle-invasive (MIBC) confirmed at final histopathological examination after TURBT. outcomes determined through sensitivity, specificity, positive likelihood ratio (PLR+), negative (PLR−), area under summary receiver operating characteristic (SROC) along their respective 95% confidence intervals (CI). Results: Overall, five studies included. In these studies, total 362 patients underwent prior sensitivity specificity 0.88 (95% CI: 0.81–0.93) 0.82–0.92), respectively. SROC curve depicted 0.94 0.81–0.98). PLR+ PLR− 7.3 4.8–11.2) 0.14 0.08–0.23), Conclusions: meta-analysis indicates highly accurate diagnosis staging BC. Beyond accuracy, offers advantage being cost-effective, safe, versatile imaging tool.

Language: Английский

Citations

9
Renal cell carcinoma of the native kidney in renal transplant recipients: case report and literature review DOI Creative Commons
Lanying Li, Haiyan Wang,

Yulan Peng

et al.

Frontiers in Oncology, Journal Year: 2025, Volume and Issue: 15

Published: April 29, 2025

Kidney transplant recipients (KTRs) carry an elevated risk of cancer-related mortality. The cumulative incidence de novo post-transplant malignancy (DPTM) reaches 10% at 10 years, with renal cell carcinoma (RCC) arising in native kidneys being the predominant urologic malignancy. This study presents three KTRs who developed kidney RCC 6-15 years post-transplantation. Notably, Case 1 demonstrated a 14.7 cm mass diagnosis, secondary to non-adherence protocol-based surveillance. Histopathological confirmation was established all cases through ISUP/WHO-graded surgical specimens and immunophenotypic profiling. exhibit risk, often nonspecific clinical presentations. Our findings emphasize critical role systematic imaging protocols, particularly ultrasonography contrast-enhanced ultrasound (CEUS), early tumor detection. Implementing these strategies may improve survival reduce disease burden this high-risk population.

Language: Английский

Citations

0
Qualitative and quantitative assessment of non-clear cell renal cell carcinoma using contrast-enhanced ultrasound DOI Creative Commons
Weiping Zhang, Jingling Wang, Li Chen

et al.

BMC Urology, Journal Year: 2024, Volume and Issue: 24(1)

Published: June 17, 2024

Abstract Background Non-clear cell renal carcinoma (nccRCC) represents a rare form of (RCC) in the clinic. It is now understood that contrast-enhanced ultrasound (CEUS) exhibits diverse manifestations and can be prone to misdiagnosis. Therefore, summarizing distinctive features ultrasonography essential for differentiation from ccRCC. Objective This study aims evaluate diagnostic efficacy qualitative quantitative CEUS diagnosing nccRCC enhance our understanding this condition. Methods We conducted retrospective analysis 21 patients with confirmed following surgery assessed characteristic conventional imaging features. The paired Wilcoxon signed-rank sum test was employed compare differences time-intensity curve (TIC) parameters between lesions normal cortex. Results Routine revealed primary characteristics cases: hypoechoic appearance (10/21, 47.6%), absence liquefaction (18/21, 66.7%), regular shape (19/21, 90.5%), clear boundaries (21/21, 100%), calcification (17/21, 81%). Color Doppler flow (CDFI) indicated low blood signal (only 1 case grade III). Qualitative demonstrated predominantly exhibited slow progression (76.1%), fast washout (57%), uniformity (61.9%), enhancement (71.5%), ring (61.9%). Quantitative such as PE, WiAUC, mTTI, WiR, WiPI, WoAUC, WiWoAUC, WOR were significantly lower than those cortex ( Z =-3.980, -3.563, -2.427, -3.389, -3.980, -3.493, -3.528, -2.763, P < 0.001, = 0.015, 0.006). However, there no significant RT, TTP, FT, or QOF (all > 0.05). Conclusion characteristics, including progression, washout, homogeneity enhancement, which aid distinguishing

Language: Английский

Citations

1
Evaluation of contrast-enhanced ultrasound for predicting tumor grade in small (≤4 cm) clear cell renal cell carcinoma: Qualitative and quantitative analysis DOI
Liang Ming,

Haolin Qiu,

Bing Ou

et al.

Clinical Hemorheology and Microcirculation, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 12

Published: July 17, 2024

The study aimed to evaluate the utility of qualitative and quantitative analysis employing contrast-enhanced ultrasound (CEUS) in predicting WHO/ISUP grade small (≤4 cm) clear cell renal carcinoma (ccRCCs).

Language: Английский

Citations

1
Differentiation of Small Clear Renal Cell Carcinoma and Oncocytoma through Magnetic Resonance Imaging-Based Radiomics Analysis: Toward the End of Percutaneous Biopsy DOI Open Access

Thibault Toffoli,

Olivier Saut,

Christele Etchegaray

et al.

Journal of Personalized Medicine, Journal Year: 2023, Volume and Issue: 13(10), P. 1444 - 1444

Published: Sept. 28, 2023

Purpose: The aim of this study was to ascertain whether radiomics data can assist in differentiating small (<4 cm) clear cell renal carcinomas (ccRCCs) from oncocytomas using T2-weighted magnetic resonance imaging (MRI). Material and Methods: This retrospective incorporated 48 tumors, 28 which were ccRCCs 20 oncocytomas. All tumors less than 4 cm size had undergone pre-biopsy or pre-surgery MRI. Following image pre-processing, 102 features evaluated. A univariate analysis performed the Wilcoxon rank-sum test with Bonferroni correction. We compared multiple pipelines normalization, feature selection, machine learning (ML) algorithms, including random forest (RF), logistic regression (LR), AdaBoost, K-nearest neighbor, support vector machine, a supervised ML approach. Results: No statistically significant identified via most effective algorithm pipeline incorporating standard RF-based LR, achieved an area under curve (AUC) 83%, accuracy 73%, sensitivity 79%, specificity 65%. Subsequently, algorithm, two groups uncorrelated established based on Pearson correlation scores. Using these features, after normalization achieving AUC 90%, 77%, 69% for distinguishing Conclusions: Radiomics MRI aid However, it is not superior multiparameter does yet allow us dispense percutaneous biopsy.

Language: Английский

Citations

3
Role of Renal Biopsy in the Management of Renal Cancer: Concordance between Ultrasound/CT-Guided Biopsy Results and Definitive Pathology, Adverse Events, and Complication Rate DOI Open Access

Gianmarco Isgrò,

Alistair Rogers,

Rajan Veeratterapillay

et al.

Journal of Clinical Medicine, Journal Year: 2023, Volume and Issue: 13(1), P. 31 - 31

Published: Dec. 20, 2023

(1) Background: In the last decade, number of detected renal cancer cases has increased, with highest incidence in Western countries. Although biopsy is reported as a safe procedure, it not adopted all centres. As possible to accurately distinguish benign tumours using imaging, this may lead overtreatment. Most on imaging treated by surgery, radiofrequency ablation (RFA), or cryotherapy. (2) Methods: This was single-centre retrospective study 225 patients studied preoperatively ultrasound (US)/CT-guided biopsy, aim supporting clinical management. Decisions regarding were based either MDT indication physician preference. US-guided first option for patients; CT-guided used when feasible. The efficacy terms diagnostic performance and concordance between results definitive pathology investigated. Additionally, adverse events related recorded analysed. Data collected throughout analysed binary logistic regression, Fisher’s exact test, Pearson’s chi-square test investigate correlations post-procedural complications size lesion. (3) Results: Renal 23/225 (10.2%) patients. A approach necessary 20/225 after failure biopsy. complication rate 4.8% overall—all Clavien grade I without any serious sequelae. Interestingly, occurred very different sizes cell carcinoma. No correlation anticoagulant/antiplatelet drugs found. seeding among who underwent partial/radical nephrectomy. (4) Conclusions: shown be effective, high low complications. use whenever failed improved

Language: Английский

Citations

2
Contrast-enhanced ultrasound of renal masses in the pre-transplant setting: literature review with case highlights DOI Creative Commons

Krister J. Barkovich,

Amanda C. Gibson, Sneh Brahmbhatt

et al.

Abdominal Radiology, Journal Year: 2024, Volume and Issue: 49(12), P. 4521 - 4530

Published: June 20, 2024

Abstract With the rising incidence of chronic kidney disease worldwide, an increasing number patients are expected to require renal transplantation, which remains definitive treatment end stage disease. Medical imaging, primarily ultrasonography and contrast-enhanced CT and/or MRI, plays a large role in pre-transplantation assessment, especially characterization lesions within native kidneys. However, with CKD/ESRD often have relative contraindications CT- MR-contrast agents, limiting their utilization this patient population. Contrast-enhanced ultrasound (CEUS), combines high temporal spatial resolution intravascular microbubble contrast provides promising alternative. This review aims familiarize reader literature regarding use CEUS evaluation cystic solid provide case examples its at our institution pre-transplant setting. Graphical abstract

Language: Английский

Citations

0
The role of radiomics in computed tomography, magnetic resonance imaging, and ultrasound for renal tumors’ diagnoses: A systematic review DOI Creative Commons

Zenghui Xi,

Jing Li, Xue Liu

et al.

Journal of Radiation Research and Applied Sciences, Journal Year: 2023, Volume and Issue: 17(1), P. 100769 - 100769

Published: Dec. 1, 2023

Radiomics is a collection of data and features obtained from medical imaging techniques. In this systematic review, various databases were comprehensively searched to understand the diagnostic role radiomics in computed tomography (CT), magnetic resonance (MRI), ultrasound (US) renal tumors. All original human studies evaluating diagnosis tumors that used CT, MRI, or US included. The findings showed many have been conducted on methods for detection benign malignant demonstrated higher sensitivity specificity compared CT MRI. It crucial conduct machine learning incorporating MR techniques more comprehensive comparisons.

Language: Английский

Citations

0