Endocrine causes of recurrent pregnancy loss in patients with post-traumatic stress disorder DOI Creative Commons
I.L. Kharun, A.V. Kaminskiy

Reproductive Endocrinology, Journal Year: 2023, Volume and Issue: 70, P. 16 - 22

Published: Dec. 29, 2023

Clarification of the etiology recurrent pregnancy loss (RPL), elucidating reasons for increase in repeated reproductive losses are an urgent topic that requires more detailed research attention. An analytical review was performed to effectively delineate our field: articles, notes, clinical protocols, monographic studies, Cochrane systematic reviews with meta-analysis, data from population-based retrospective cohort etc. A listed literature sources and analysis available on association between endocrine dysfunction, post-traumatic stress disorder risk acute respiratory distress syndrome were performed. Research this area will be important understanding mechanisms cause RPL, development effective prevention treatment strategies aimed at improving health women traumatic experience RPL.The frequency premature termination is 10–25%, part RPL segment than 5%. Unfortunately, there currently no positive developments regarding reduction frequency. The modern studies show causes: disorders system; genetic factors, erased forms adrenal gland dysfunction; lesions endometrium receptor apparatus, which clinically manifested luteal phase insufficiency; chronic endometritis persistence conditionally pathogenic microorganisms and/or viruses; cervical uterine malformations, intrauterine synechiae; antiphospholipid other autoimmune disorders.Endocrine such as polycystic ovary syndrome, hyperandrogenism, hyperprolactinemia, thyroid insulin resistance, type 2 diabetes mellitus analyzed establish dysfunction importance a holistic approach diagnosis has been demonstrated. It necessary take into account patient’s emotional mental state, particular, signs disorder, can significantly affect ratio sex hormones, ther№efore 5-6(7, c0)/грause eуденьxacerba 2023 WWWtion diseases w.REPRODUCT-ENDOoman diabet.COM / es mellitusWWW, aut. oimmune thREPRODUCT-ENDOyroiditis, h.CypothOM.yrUAoidism, others.

Language: Английский

Transmission of Human Life with a Gestational Carrier DOI Open Access
Carlo Bulletti

Biomedical Journal of Scientific & Technical Research, Journal Year: 2023, Volume and Issue: 52(2)

Published: Aug. 17, 2023

Infertility is a disease of the male or female reproductive system associated with psychological default. Surrogacy, pregnancy for others, gestational carrier method assisting transmission human life. Several severe acquired congenital conditions require unique medical solution- use carrier-with only alternative option uterine transplantation from third woman to carry on pregnancy.

Language: Английский

Citations

3
Hypercoagulability linked to pregnancy in a group of Colombian patients, observational study of binding clinical and laboratory alterations. DOI Creative Commons

Maria Amaya,

Luis Dulcey,

Juan Theran

et al.

Published: Sept. 17, 2023

Introduction: The present study sought to thrombophilias associated with venous thromboembolism during pregnancy. Methods: is of a descriptive observational type in which the clinical and laboratory alterations were analyzed cohort Latin American pregnant women denominator thrombotic events Results: mean age was 24.5+7.6 years, 9 patients (10.3%) had history , 23 (26.4%) at least one fetal loss. Elevated Antiphosphatidylserine antibodies found (26.4%), elevated against Beta2-Glycoprotein 20 (22.9%), positive lupus anticoagulant 16 (18.3%), Factor VIII 13 (14.94%), IX 15 (17.2%), XI 12 (13.7%), Prothrombin Mutation 7 (8.07%). Conclusions: results here indicate high prevalence rate thrombophilic alterations. underdiagnosed women.

Language: Английский

Citations

1
Novel nucleotide variations in the thrombomodulin (THBD) gene involved in coagulation pathways can increase the risk of recurrent pregnancy loss (RPL) DOI
Mohammad Heidari,

Bahareh Mazrouei,

Maryam Tahmasebi

et al.

Gene, Journal Year: 2023, Volume and Issue: 895, P. 148011 - 148011

Published: Nov. 17, 2023

Language: Английский

Citations

1
Condiciones trombofilicas y su riesgo en una cohorte latinoamericana de gestantes, estudio observacional descriptivo DOI Open Access
Diana Marcela Villamizar Olarte, Luis Dulcey

Revista de Obstetricia y Ginecología de Venezuela, Journal Year: 2024, Volume and Issue: 84(01), P. 33 - 41

Published: Feb. 22, 2024

Objective: To evaluate thrombophilias associated with venous thromboembolism during pregnancy. Methods: Descriptive observational study. Clinical and laboratory alterations were analyzed, as well the classification of related profile a cohort Latin American pregnant women thrombotic events gestation up to 120-day puerperium. Antiphospholipid syndrome antibodies, coagulation protein C, S, antithrombin III, mutations against factor V Leiden, in methylenetetrahydrofolate reductase, hyperhomocysteinemia, prothrombin mutation, elevation factors VIII, IX, XI performed. Results: The mean age was 24,5 + 7,6 years, which 9 patients (10,3%) had history thromboembolism, 23 (26,4%) at least one fetal loss. Elevated antiphosphatidylserine antibodies found (26,4%), elevated beta2-glycoprotein 20 (22,9%), positive lupus anticoagulant 16 (18,3%), VIII 13 (14,94%), IX 15 (17,2%), 12 (13,7%), mutation 7 (8,07%) others lesser extent. Conclusions: results here point high prevalence rate underdiagnosed thrombophilic disorders women. There is still lack strong evidence analyze this relationship worse Keywords: Coagulation, Thrombosis, Gynecology.

Language: Английский

Citations

0
Moderating Role of Sense of Coherence on the Relationship between Grief and Embitterment among Women's Experiences Fetal Demise/Spontaneous Abortion DOI Creative Commons
Rizwana Samreen, Samina Rashid,

Babar Nadeem

et al.

Qlantic journal of social sciences., Journal Year: 2024, Volume and Issue: 5(2), P. 424 - 432

Published: June 30, 2024

A time of anticipation and support, bearing a child is an emotional journey defined by the promise certainty new life. However, some individuals couples have deep often tragic experience in middle this joy expectation: fetal demise/ spontaneous abortion. The intention current study to examine association between grief embitterment for females who undergone also aims explore buffering impact sense coherence on embitterment. Data from 200 married women experienced abortion was collected person online using purposive sampling technique. For data collection, three reliable scales were used, namely Perinatal Grief Scale (PGS) grief, Traumatic Embitterment Disorder Self-Rating (PTED) embitterment, Sense Coherence (SOC) scale measuring coherence. Results suggest positive relationship As increases, increases. helps decrease significantly moderates implications examined.

Language: Английский

Citations

0
New aspects of immunological risk factors in the treatment of recurrent pregnancy loss DOI Creative Commons

Gultakin Aliyeva,

Samangul Tarverdiyeva,

Matlab Ibrahimov

et al.

Healthcare in Low-resource Settings, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 8, 2024

Recurrent Pregnancy Loss (RPL) is diagnosed in 3% of all patients reproductive age and high interest to medicine specialists. Immunological predispositions are among the crucial risk factors for RPL development female suffering from RPL. Therefore, purpose this work investigate role effectiveness individualised immunological treatment approaches by analysing several clinical cases with pregnancy loss results tailored therapies. Based on 25 years experience scientific research paper analysed relationship between Human Leukocyte Antigens (HLA) tissue compatibility ABO blood group system incompatibility failure. The connection these was shown 2 who agreed participate research. Research performed at Nakhchivan Birth Center State University. study provided evidence based that ended successful childbirth after suggested genetic assessment treatment. Individual failure HLA incompatibilities showed more effective outcomes if compared previous schemes loci 3 combined affinity strongly demanded therapy prescription implantation blastocyst. obtained can be implemented obstetrics gynecology improvement

Language: Английский

Citations

0
ВЕДЕННЯ ВАГІТНОСТІ У ЖІНОК ІЗ ВИЛІКУВАНИМ БЕЗПЛІДДЯМ НА ТЛІ СИНДРОМУ ГІПЕРПРОЛАКТИНЕМІЇ DOI Open Access
О. М. Носенко,

О. В. Мартиновська

Актуальні питання педіатрії акушерства та гінекології, Journal Year: 2024, Volume and Issue: 1, P. 53 - 62

Published: April 15, 2024

Мета дослідження – визначити особливості перебігу вагітності та пологів у жінок із вилікуваним безпліддям внаслідок синдрому гіперпролактинемії (СГПРЛ) на тлі ідіопатичної (ІГ) або мікропролактином (МП) й ефективність гормональної підтримки такої дидрогестероном. Матеріали методи. Спостереження охоплювало 78 безплідних СГПРЛ МП ІГ, яких лікування каберголіном настала вагітність. Після настання жінки основної групи О (n=32) отримували дидрогестерон до 20 тижнів вагітності, вітамінно-мінеральні комплекси, при високих цифрах сироваткового пролактину (ПРЛ) каберголін нормалізації рівнів ПРЛ; порівняння П (n=30) вели відповідно існуючих стандартів ведення вагітності. Контрольну групу К склали 30 умовно здорових фертильних без нейроендокринних порушень. Досліджено гормональний профіль сироватки периферичної крові в динаміці безпліддя, сироваткові рівні ПРЛ терміни 11–12, 18–20, 30–31 і 36–37 тижнів, результати пологів. Результати їх обговорення. До початку статус характеризувався підвищеним рівнем вільного тестостерону, зниженими сироватковими концентраціями фолікулостимулювального лютеїнізуючого гормонів, естрадіолу прогестерону. Безперервне займало середньому (6,21±0,16) міс. Овуляція відновилася через (5,27±0,13) Вагітність була досягнута (8,04±0,19) Проведення запропонованого привело групі зниження частоти загрози викидня 3,47 раза (СШ 0,1868 [0,0610–0,5723]), дисфункції плаценти 5,07 (CШ 0,0827 [0,0266–0,2567]), викиднів 12,92 0,0585 [0,0069–0,4971]), передчасного розриву плодових оболонок 3,60 0,2121 [0,0585–0,7686]). Передчасні пологи були 36,36 % випадків, усі терміновими (p<0,01). Висновки. Тривале ІГ відновлює фертильність, а застосування дидрогестерону першій половині призводить вірогідного гестаційних акушерських ускладнень.

Citations

0
Association of MTR and MTRR polymorphisms with recurrent pregnancy loss: a case control study DOI
Mai M. Shaker, Nesma M. Elaraby, Taghreed A. Shalabi

et al.

Molecular Biology Reports, Journal Year: 2024, Volume and Issue: 51(1)

Published: Sept. 9, 2024

Language: Английский

Citations

0
High Prevalence of Anti-Prothrombin IgM and IgG Autoantibodies in Women With Unexplained Recurrent Pregnancy Loss DOI

Ramzi R. Finan,

Nisrine Beydoun,

Eddie Racoubian

et al.

Reproductive Sciences, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 7, 2024

Language: Английский

Citations

0
Risk factors associated with pregnancy outcomes in patients with recurrent pregnancy loss after treatment DOI Creative Commons
Tingfeng Fang, Xiaohui Ji, Zhen Su

et al.

BMC Pregnancy and Childbirth, Journal Year: 2024, Volume and Issue: 24(1)

Published: Dec. 19, 2024

Language: Английский

Citations

0