Age- and sex-adjusted CT-based reference values for temporal muscle thickness, cross-sectional area and radiodensity
Emilia K Pesonen,
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Otso Arponen,
No information about this author
Jaakko Niinimäki
No information about this author
et al.
Scientific Reports,
Journal Year:
2025,
Volume and Issue:
15(1)
Published: Jan. 18, 2025
Muscle
mass
has
been
traditionally
assessed
by
measuring
paraspinal
muscle
areas
at
the
level
of
third
lumbar
vertebra
on
computed
tomography
(CT).
Neurological
or
neurosurgical
patients
seldom
undergo
CT
scans
region.
Instead,
temporal
thickness
(TMT),
cross-sectional
area
(TMA)
and
radiodensity
measured
from
head
are
readily
available
measures
quality
in
these
patient
cohorts.
The
purpose
this
retrospective
study
was
to
establish
CT-based
reference
values
for
TMT,
TMA
each
decade
age
0
100
years
normalized
sex,
define
cut-off
subjects
risk
sarcopenia
as
defined
European
Working
Group
Sarcopenia
Older
People
(EWGSOP).
Subjects
diagnosed
with
a
concussion
Oulu
University
Hospital
between
January
2014
December
2022
(n
=
9254)
were
identified
obtain
population.
significant
pre-existing
co-morbidities
excluded.
measured,
measurement
reliability
quantified,
sex-adjusted
calculated
decade.
Quantile
regression
used
model
age-related
changes
morphomics.
A
total
500
[250
(50.0%)
males]
mean
49.2
±
27.9
evaluated.
Inter-
intra-observer
almost
perfect
TMT
TMA,
substantial-to-almost
radiodensity.
5.2
1.9
mm,
284
159
mm2
44.6
17.7HU,
respectively.
reduced
males/females
using
compliant
criteria
≤
4.09
mm/≤3.44
166
mm2/≤156
mm2,
35.5HU/≤35.2HU,
We
described
standardized
protocol
practical
clinical
use
reliability.
Using
protocol,
we
produced
quantile
models
detection
lowest
5th,
10th,
20th,
30th,
40th
50th
percentiles
well
EWGSOP
facilitate
generalizable
radiological
research.
Language: Английский
The velocity of temporalis muscle wasting in cerebral metastasis is prognostic for poor survival
Frontiers in Oncology,
Journal Year:
2025,
Volume and Issue:
15
Published: Feb. 28, 2025
Purpose
Recently,
the
temporalis
muscle
thickness
on
cranial
CT
scan
was
proposed
as
a
surrogate
marker
for
patients’
baseline
frailty
that
correlates
with
outcome
in
primary
and
metastatic
brain
tumor
patients.
In
this
study,
we
investigated
whether
velocity
of
atrophy
(TMA)
affects
patients
cerebral
metastases.
Methods
We
analyzed
radiological
clinical
data
sets
96
who
received
craniotomy
metastasis
resection
our
institution.
then
correlated
course
after
stratification
atrophy.
Results
The
median
TMA
0.0016
mm/day.
slow
rate,
overall
survival
significantly
longer
than
fast
rate
(37.7
months
versus
22.9,
p
=
0.0007).
Furthermore,
had
progression-free
postoperatively
(7.6
4.38
months,
<0.0001).
(OS-PO)
also
(8.9
5.1,
p=0002).
Conclusion
Based
may
represent
an
objective
dynamic
index
potential
prognostication
Language: Английский
Temporal muscle thickness and index predict overall survival after surgical evacuation of spontaneous intracerebral hemorrhage
Emilia K Pesonen,
No information about this author
Otso Arponen,
No information about this author
Jaakko Niinimäki
No information about this author
et al.
Clinical Neurology and Neurosurgery,
Journal Year:
2025,
Volume and Issue:
254, P. 108962 - 108962
Published: May 12, 2025
The
prognosis
of
spontaneous
intracerebral
hemorrhage
(ICH)
is
poor,
but
an
accurately
selected
subset
patients
benefits
from
surgery.
Loss
muscle
mass
associated
with
various
geriatric
syndromes
and
poor
overall
physiological
capacity.
We
investigated
whether
temporal
thickness
(TMT)
index
(TMI),
non-invasive
indicators
whole-body
mass,
predict
survival
(OS)
in
surgically
treated
ICH.
identified
all
evacuated
spontenous
supratentorial
ICHs
a
single
centre
between
2014
2022.
measured
TMT
TMI
preoperative
computed
tomography
scans,
tested
the
prognostic
capability
these
measurements
for
post-operative
OS.
Cut-off
values
were
calculated
to
divide
into
low
normal
status
groups
according
TMI.
median
age
63
included
study
was
67
years
(IQR
57-72),
37
(59
%)
males.
mortality
during
follow-up
period
36
months
1-79)
significantly
higher
group,
as
assessed
using
cut-offs
(67
%
vs.
30
%,
HR
2.65,
95
CI
1.23-5.65,
31
2.37,
1.11-5.04,
respectively).
association
persisted
when
adjusted
ICH
score,
pupillary
blood
pressure
on
admission
(TMT
2.75,
1.27-5.96,
2.30,
1.07-4.97).
provide
information
supplemental
established
outcome
predictors
These
parameters
may
improve
surgical
patient
selection
detection
at
risk
outcomes
who
might
benefit
intensified
ancillary
care.
Language: Английский
Prognostic value of temporalis muscle thickness as a marker of sarcopenia in intracerebral hemorrhage
Waldemar Gubarev,
No information about this author
Jan Klinke,
No information about this author
Ulrike Voßmann
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et al.
Frontiers in Neurology,
Journal Year:
2025,
Volume and Issue:
16
Published: May 16, 2025
Introduction
Estimating
the
prognosis
of
spontaneous
intracerebral
hemorrhage
(ICH)
is
great
importance.
It
has
not
been
conclusively
clarified
whether
sarcopenia
predictive
for
functional
outcome
in
ICH.
Determining
temporalis
muscle
thickness
(TMT)
may
be
helpful
estimating
sarcopenia.
An
association
TMT
with
(mRS)
shown
cerebellar
ischemia
and
traumatic
brain
injury.
Methods
The
present
retrospective
study
488
consecutive
patients
ICH
aimed
to
investigate
as
assessed
by
mRS.
In
addition
biometric
data,
subtype
severity
[modified
score
(mICH)],
occurrence
complications
mRS
at
discharge
after
90
days
were
recorded.
influence
surrogate
marker
using
head
imaging
(cCT,
cMRT)
on
was
analyzed
ordinal
regression
analysis.
Dichotomization
into
sarcopenic
non-sarcopenic
carried
out
standard
threshold
values.
Results
Finally,
322
[median
(IQR)
age:
77
(66–83)
years;
57.5%
male].
Sarcopenic
older
(
P
<
0.001),
had
lower
BMI
=
0.025)
higher
mICH
scores
0.001)
compared
patients.
There
no
significant
difference
overall
distribution
between
(unadjusted
common
OR:
1.28;
95%
CI:
0.85–1.92;
0.236),
but
favoring
over
group
1.41;
1.07–2.12;
0.049).
results
did
subsist
statistical
adjustment
candidate
covariates
multivariate
regression.
Discussion
conclusion,
seems
have
limited
prognostic
value
Language: Английский