Prevalence, spectrum, and the relations between short-term and long-term post-acute sequelae of COVID-19 in children
Journal of microbiology epidemiology immunobiology,
Journal Year:
2025,
Volume and Issue:
102(1), P. 43 - 61
Published: March 30, 2025
Background.
Data
on
the
prevalence
of
post-COVID-19
condition
(PCC)
in
children
differ
due
to
lack
specific
diagnostic
criteria,
reliable
biomarkers,
and
limitations
many
studies.
It
is
important
study
association
between
PCC,
previous
functional
disorders,
any
events
post-acute
period
COVID-19
estimate
true
burden
PCC
children.
The
aim.
To
determine
relation
initial
disorders
during
year
after
a
mild
form
acute
respiratory
tract
infections
(ARTI)
other
etiologies.
Materials
methods.
prospective
using
continuous
sampling
method
included
under
18
years
age
hospitalized
with
suspected
COVID-19,
whom
was
confirmed
by
RT-PCR
(n
=
121)
or
excluded
molecular
serological
methods
(ARTI
group,
n
105).
Information
patients
collected
from
September
2020
December
2021
questionnaires
at
index
points:
hospital
discharge
1,
3,
6
12
months.
Severe
chronic
diseases
were
excluded.
Functional
anamnesis
associated
health
observation,
severity
symptoms
taken
into
account.
analysis
performed
groups
≥
age.
Symptoms
grouped
clusters.
Results.
Any
identified
frequency
32–39%
(in
≥6
years,
respectively).
most
common
psycho-emotional,
autonomic
dysfunction
(AD)
cluster.
cases
duration
3–6
After
adjustment
for
age,
AD
history
recurrent
ARTI
episodes,
no
difference
found
symptom
clusters
except
hyposmia,
incidence
which
decreased
14.3%
first
point
2.4%
one
year.
Among
without
an
year,
de
novo
rare
phenomenon
(2.7–8.0%)
differences
controls.
risks
significantly
increased
(adjusted
OR
1
month
3.19
(95%
CI
1.89–5.38),
months
3.33
1.81–6.15)).
Multiple
(5–25)
persistent
(at
all
points)
rated
as
significant
occurred
rarely
(1.7%
0.4–4.9)),
but
more
often
—
25%)
95%
13.6–39.6%)
(difference
23.3%
(10.9–35.7%),
14.8
(4.4–50.6),
p
0.001).
Recurrent
episodes
risk
factor
increase
cognitive
cluster
complaints
vagotonic
observation.
Conclusion.
results
obtained
indirectly
support
concept
that
somatoform
disorder,
probably
sociogenic
nature,
who
are
anxious
baseline.
Some
consequences
really
need
medical
psychosocial
rehabilitation.
provides
new
insights
widespread
viral
infections.
Language: Английский
Navigating an unfamiliar world – Parents' experiences of having a child with post COVID-19
Journal of Pediatric Nursing,
Journal Year:
2024,
Volume and Issue:
77, P. e565 - e572
Published: May 25, 2024
Language: Английский
Clinical insights: Resolving the specter of cardiac sequelae in multisystem inflammatory syndrome in children (MIS-C) – A 24-month follow-up case series
Progress in Pediatric Cardiology,
Journal Year:
2024,
Volume and Issue:
75, P. 101759 - 101759
Published: Oct. 10, 2024
Language: Английский
Long-term gastrointestinal symptoms and sleep quality sequelae in adolescents after COVID-19: a retrospective study
Wei-Lin Yang,
No information about this author
Qi Wang,
No information about this author
Ying Wang
No information about this author
et al.
Frontiers in Public Health,
Journal Year:
2024,
Volume and Issue:
12
Published: May 21, 2024
Objective
To
evaluate
the
long-term
gastrointestinal
(GI)
symptoms
and
sleep
quality
sequelae
in
adolescents
with
COVID-19.
Methods
Between
June
July
2023,
an
online
survey
was
done
Xiaoshan
District,
Hangzhou
City,
Zhejiang
Province,
China,
using
GI
Symptom
Rating
Scale
(GSRS)
Pittsburgh
Sleep
Quality
Inventory
(PSQI).
Results
COVID-19
patients
increased
by
11.86%
compared
to
before
infection,
while
decreased
10.9%.
Over
time,
there
a
significant
increase
cumulative
incidence
rate
of
disorders
(
p
<
0.001).
Follow-up
positive
within
6
months
infection
showed
that
began
ease
starting
from
first
month
after
infection.
Further
analysis
indicated
linear
relationship
between
severity
(R
>
0.5,
Moreover,
females,
older
age,
higher
education
were
identified
as
risk
factors
influencing
effects
Conclusion
SARS-CoV-2
affects
during
both
acute
phase
post-infection
periods.
these
gradually
alleviate.
A
correlation
exists
quality.
Language: Английский
Post-infection gastrointestinal disorders and treatment options
Meditsinskiy sovet = Medical Council,
Journal Year:
2024,
Volume and Issue:
11, P. 84 - 91
Published: Aug. 6, 2024
The
development
of
post-infectious
pathology
is
determined
by
the
type
pathogen,
genesis
damage
to
intestinal
barrier
and
premorbid
background
child.
On
scale
recent
epidemiological
events,
attention
drawn
SARS-CoV-2
virus,
which
has
tropism
for
cells
gastrointestinal
tract,
distorts
composition
function
microbiome.
importance
functions
microbes
in
outcome
infection
been
highlighted.
It
proven
that
a
microbiota
disorder
with
new
coronavirus
affects
not
only
duration
severity
infectious
process,
but
also
risk
formation
systemic
diseases
malignant
neoplasms.
After
acute
phase
infection,
post-COVID-19
syndrome
may
occur,
pathophysiology
yet
fully
established.
Although
it
believed
main
reason
its
appearance
diversification
microbial
landscape
against
direct
effect
on
ACE2
receptors
epitheliocytes,
followed
pathoimmune
response
impaired
hemostasis.
Established
dysbiosis
underlies
functional
disorders
pronounced
impairment
brain-gut-microbiota
axis
imbalance
migrating
motor
complex,
leading
constipation.
Post-infectious
constipation
debut
within
first
3
months
after
an
infection.
goal
therapy
achieve
regular
painless
defecation
soft-consistency
stool
prevent
feces.
Numerous
foreign
studies
clinical
guidelines
indicate
stimulating
laxatives
are
effective
safe
treatment
constipation,
include
children’s
practice.
Sodium
picosulfate
considered
one
topical
drugs
this
group
laxatives.
Language: Английский
Perspective Chapter: Sequelae and Consequences of COVID-19 in the Paediatric Population
Víctor Manuel Gutiérrez Gómez,
No information about this author
Lenin Ortiz-Ortega,
No information about this author
Beatriz X. Pasco-Velázquez
No information about this author
et al.
IntechOpen eBooks,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 25, 2024
During
the
pandemic
and
in
subsequent
years,
we
observed
that
COVID-19
caused
by
SARS-CoV-2
virus
affected
paediatric
population
different
ways.
In
certain
groups
of
children
adolescents,
social
isolation,
changes
family
dynamics,
increased
exposure
to
technological
screens
diet,
among
others,
have
their
development,
education,
emotional,
physical
aspects,
including
access
immunizations,
medical
surveillance
control.
is
considered
a
generally
benign
pathology
children;
however,
some
patients
develop
well-defined
post-COVID-19
entities:
multisystem
inflammatory
syndrome
(MIS-C)
long
COVID.
this
chapter,
review,
relation
population,
effects
confinement
during
its
development
consequences,
forms
clinical
presentation
entities
MIS-C
COVID,
prevalence,
pathophysiology,
presentation,
evolution,
detection
management
recommendations.
Language: Английский