Prognostic factors in hospitalized patients with COVID-19 pneumonia and effectiveness of prophylactic anticoagulant therapy: a single-center retrospective study

BMC Infectious Diseases, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 3, 2025

Abstract Background COVID-19 pneumonia patients encounter the potential risk of venous thromboembolism (VTE) and mortality during hospitalization. This study aimed to analyzed factors all-cause in hospitalized with pneumonia, investigated effectiveness prophylactic anticoagulation hospital stays on nonVTE. Methods We retrospectively all who were admitted our medical center from December 2022 January 2023. Clinical data outcome events collected patients’ electronic records. Cox regression was used identify poor prognostic VTE Landmark analysis conducted time points between treatment in-hospital survival outcomes Binary logistic performed investigate related prolonged stays. Results Among 2,520 patients, 1047 received 76 complicated Survival curve showed no statistically significant difference nonVTE anticoagulant group ( P = 0.63). Multivariate cox revealed that male(HR 1.398, 95%CI= [1.021,1.915]), BMI (HR 0.935, [0.900,0.972]), lymphocytes 0.576, [0.409,0.809]), platelets 0.997, [0.995,0.999]), albumin 0.950, [0.926,0.975]), lactate dehydrogenase 1.001, [1.001,1.002]) for nonVTE, while sCRP 1.010, [1.004,1.015]), therapy 0.247, [0.096,0.632]) VTE. 11 days, impact (≤ 11days, 0.014; > 0.01). CVD (OR 1.717, [1.248,2.363]), CRD 1.605, [1.133,2.274]), 1.003, [1.000,1.006]), Alb 0.959, 95%CI [0.932,0.987]) use glucocorticoid 1.428, [1.057,1.930]) independent associated days group. Conclusions indicated Male, lower BMI, peripheral blood lymphocytes, platelets, elevated hospitalisation As VTE, levels given therapy. No when receiving anticoagulation. Prolonged (> days) may limit

Language: Английский

A tri-light warning system for hospitalized COVID-19 patients: Credibility-based risk stratification for future pandemic preparedness

European Journal of Radiology Open, Journal Year: 2024, Volume and Issue: 13, P. 100603 - 100603

Published: Oct. 17, 2024

Language: Английский