Giant cell tumor of the tendon sheath: A critical review of current diagnostic and therapeutic approaches with treatment recommendations for hand and foot lesions DOI
J. Terrence Jose Jerome,

Dharani Karunanithi

Journal of Musculoskeletal Surgery and Research, Journal Year: 2024, Volume and Issue: 9, P. 28 - 41

Published: Dec. 2, 2024

Giant cell tumor of the tendon sheath (GCTTS) is a common affecting hand and foot, often presenting diagnostic therapeutic challenges due to its variable clinical presentations biological behaviors. Recent evidence supports neoplastic origin for this tumor, previously known by various names. GCTTS can be categorized as localized or diffuse, with distinct predilections specific anatomical locations. While typically benign more in wrist, diffuse form aggressive, also foot ankle. This critical analysis review aims provide comprehensive overview encompassing clinical, radiological, histological, genomic features. In addition, we summarize current management practices, discuss differential diagnoses, analyze recurrence rates following surgical excision, offer evidence-based treatment recommendations diverse group tumors.

Language: Английский

Giant cell tumour DOI Creative Commons

Enzo Redolfi Mema

Radiopaedia.org, Journal Year: 2025, Volume and Issue: unknown

Published: March 2, 2025

Citations

0
Intramuscular Soft Tissue Giant Cell Tumor of the Forearm: A Case Report DOI Creative Commons
Kaissar Yammine, Emanuel‐Youssef Dib,

Mohammed Ghanem

et al.

Clinical Case Reports, Journal Year: 2025, Volume and Issue: 13(4)

Published: March 28, 2025

We report the case of a 33-year-old female who presented with painful, rapidly growing mass on her left dorsal forearm. Physical examination revealed 2 cm firm, well-demarcated, non-erythematous nodule beneath skin, an initial diagnosis lipoma. Upon removal, was found to be intramuscular antebrachial fascia. The histopathology confirmed benign giant cell tumor soft tissue (GCT-ST). patient informed potential risk recurrence, and regular follow-up recommended. At last follow-up, no clinical evidence recurrence noted. This highlights rare GCT at exceptional location,

Language: Английский

Citations

0
Diagnostic Challenge of Localized Tenosynovial Giant Cell Tumor in Children DOI Creative Commons
Jiro Ichikawa, Satoshi Ochiai, Tomonori Kawasaki

et al.

Diagnostics, Journal Year: 2025, Volume and Issue: 15(3), P. 281 - 281

Published: Jan. 24, 2025

This report describes a rare case of pediatric tenosynovial giant cell tumor (TSGCT) with delayed diagnosis. A 9-year-old boy presented 3-month history knee pain and swelling, initially attributed to femoral non-ossifying fibroma arthritis based on computed tomography findings slightly elevated C-reactive protein levels. The symptoms persisted despite medical treatment. Magnetic resonance imaging (MRI) revealed in the posterior compartment. He underwent surgery, pathology confirmed diagnosis localized TSGCT. Six months postoperatively, patient remained asymptomatic. Pediatric is complex symptom associated inflammatory conditions benign malignant tumors. Benign tumors, as this case, can be misdiagnosed arthritis, delaying MRI recommended cases involving persistence. However, histopathological, immunohistochemical, morphological examinations are crucial for definitive diagnosis, particularly when inconclusive.

Language: Английский

Citations

0
Arthroscopic Management of Pigmented Villonodular Synovitis of the Hip: A Systematic Review DOI Open Access
Riccardo Giai Via, Matteo Giachino, Ahmed Elzeiny

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(21), P. 6446 - 6446

Published: Oct. 28, 2024

Background/Objectives: Pigmented villonodular synovitis (PVNS) is a benign proliferation of synovial tissue that can cause joint damage. The hip, although less commonly affected than the knee, presents challenging diagnosis and treatment, with magnetic resonance imaging (MRI) as gold standard for detection. Surgical excision, arthroscopic or open, main treatment approach, but there no consensus on best strategy hip. aim this systematic review to evaluate clinical outcomes, complications, revision rates associated hip surgery PVNS. Methods: A was performed following PRISMA guidelines. Relevant studies were identified by searching four databases: PubMed, Scopus, Embase, Medline. Selected articles evaluated according criteria levels evidence (LoE). For retrospective studies, Coleman Methodology Score (mCMS) used. This registered International Prospective Register Systematic Reviews. Results: Six satisfied criteria; these involved 77 patients (48% male, 52% female) mean age 26.4 years follow-up 54.3 months. MRI biopsy confirmed diagnoses, synovectomy primary treatment. Success ranged from 80% 100%, recurrence rate 7.8%, 1.3% requiring surgery, eight (10.4%) in three reporting conversion THA. Complications included mild effusions residual synovitis. All who underwent subsequent total arthroplasty advanced osteoarthritis. Conclusions: Our reveals use arthroscopy diagnosing treating PVNS has shown satisfactory results without increasing risk complications return their former activity levels, provided preoperative osteochondral status good early management joint.

Language: Английский

Citations

0
Giant cell tumor of the tendon sheath: A critical review of current diagnostic and therapeutic approaches with treatment recommendations for hand and foot lesions DOI
J. Terrence Jose Jerome,

Dharani Karunanithi

Journal of Musculoskeletal Surgery and Research, Journal Year: 2024, Volume and Issue: 9, P. 28 - 41

Published: Dec. 2, 2024

Giant cell tumor of the tendon sheath (GCTTS) is a common affecting hand and foot, often presenting diagnostic therapeutic challenges due to its variable clinical presentations biological behaviors. Recent evidence supports neoplastic origin for this tumor, previously known by various names. GCTTS can be categorized as localized or diffuse, with distinct predilections specific anatomical locations. While typically benign more in wrist, diffuse form aggressive, also foot ankle. This critical analysis review aims provide comprehensive overview encompassing clinical, radiological, histological, genomic features. In addition, we summarize current management practices, discuss differential diagnoses, analyze recurrence rates following surgical excision, offer evidence-based treatment recommendations diverse group tumors.

Language: Английский

Citations

0