Treatment of Medication-Related Osteonecrosis of the Jaw Without and With the Use of Advanced Platelet-Rich Fibrin: A Retrospective Clinical Study
Paulina Adamska,
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Marcin Stasiak,
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Natalia Kobusińska
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et al.
Journal of Functional Biomaterials,
Journal Year:
2025,
Volume and Issue:
16(5), P. 180 - 180
Published: May 14, 2025
Medication-related
osteonecrosis
of
the
jaw
(MRONJ)
is
drug-induced
bone
destruction
that
exposed
for
a
minimum
6
to
8
weeks
in
patients
who
have
not
received
head
and
neck
radiotherapy
been
diagnosed
with
facial
metastases.
MRONJ
treatment
outcomes
are
unpredictable.
Therefore,
alternative
methods
being
explored,
such
as
blood-derived
platelet-rich
preparations
enriched
growth
factors,
including
advanced
fibrin
(A-PRF).
The
presence
factors
may
enhance
healing
reduce
post-procedure
complications.
There
no
studies
examining
effect
A-PRF
on
MRONJ.
aim
this
study
was
retrospectively
evaluate
surgically
treated
without
use
A-PRF.
This
retrospective
included
28
suffered
from
osteomyelitis
due
underwent
surgical
between
2019
2024.
were
divided
into
two
groups:
first
group
A-PRF,
second
application
analyzed
demographic
clinical
data,
well
outcomes.
aged
43
82
years.
most
common
cause
administration
zoledronic
acid
oncological
reasons
(22
patients,
78.6%),
given
intravenously.
In
20
(71.4%),
antiresorptive
lasted
longer
than
three
obtained
distribution
binomial
(presence
or
absence
healing).
Estimation
probability
using
maximum
likelihood
method
provided
result
approximately
64%.
ten
more
healed
41%.
helps
59%,
it
lower.
Concomitantly,
differences
statistically
significant.
should
regular
check-ups
radiological
examinations
at
least
every
six
months
detect
possible
recurrence.
Treatment
long
difficult.
non-advanced
lesions,
additional
risk
(such
zoledronate
intravenously
purposes
3
years),
showed
better
prognosis.
Sometimes,
addition
surgery,
necessary
consider
methods.
healing.
However,
there
evidence
significant
Language: Английский
A Histologic Study on the Use of Tooth as a Graft Material in Oral Surgery: Analysis of 187 Samples
Materials,
Journal Year:
2025,
Volume and Issue:
18(11), P. 2518 - 2518
Published: May 27, 2025
Background:
To
reconstruct
and
maintain
hard
tissues
over
time,
it
is
necessary
to
follow
effective
protocols
use
appropriate
materials.
The
selection
of
the
graft
material
its
properties
can
also
affect
final
outcomes.
For
this
purpose,
numerous
materials
have
been
suggested.
Among
valuable
alternatives
these
biomaterials,
interest
in
using
teeth
as
has
grown
recent
years.
Aim:
aim
study
was
investigate
histomorphometric
outcomes
tooth-derived
when
used
a
bone
substitute.
Methods:
We
evaluated
histological
results
autologous
demineralized
tooth
prepared
Tooth
Transformer
device.
A
total
187
samples
from
186
subjects
(52%
male
48%
female,
with
an
average
age
56.30
±
12.97
years)
were
analyzed.
analysis
focused
on
volume
(BV%),
residual
(residual
graft,
TT%),
vital
(VB%).
differences
between
presence
absence
resorbable
membrane
Results:
amount
VB
36.28
19.09%,
TT
9.6
10.76%,
46.96
13.85%
(BV).
increased
BV%
reduced
time
produce
bone.
Conclusions:
procedure
biomaterial
may
be
predictable
method
for
producing
new
capable
supporting
dental
implant
rehabilitation
allow
better
results.
Language: Английский
Treatment of Oroantral Communication and Fistulas with the Use of Blood-Derived Platelet-Rich Preparations Rich in Growth Factors: A Systematic Review
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(21), P. 11507 - 11507
Published: Oct. 26, 2024
The
formation
of
an
oroantral
communication
(OAC)
or
fistula
(OAF)
is
a
rare
complication
resulting
from
the
presence
processes
in
lateral
parts
maxilla
for
iatrogenic
reasons.
most
common
causes
OAC
OAF
are
tooth
extraction
with
periapical
lesions.
aims
this
systematic
review
were
to
assess
use
platelet-derived
preparations
rich
growth
factors
treatment
OAF,
determine
success
treating
fistula,
as
well
impact
on
postoperative
complications
and
course
healing.
study
was
performed
following
PRISMA
guidelines
(PROSPERO:
CRD42024570758).
inclusion
criteria
follows:
at
least
ten
patients,
factors,
information
regarding
response
treatment.
In
order
find
relevant
studies,
international
databases,
including
PubMed,
Google
Scholar,
Web
Science
Core
Collection,
MDPI,
Wiley,
Cochrane
Library
searched.
last
search
31
August
2024.
Seven
articles
included
review.
total,
used
164
patients.
Only
studies
which
treated
platelet-rich
fibrin
(PRF)
met
criteria.
PRF
sole
method
three
studies.
When
greater
than
5
mm,
should
be
considered
adjuncts
treatment,
not
method.
rate
90–100%.
blood
products
close
may
effective
therapeutic
alternative.
Proper
patient
qualification
appropriate
protocol
crucial.
There
need
future
well-designed
case-control
cohort
randomized
controlled
trials
provide
required
level
evidence.
Language: Английский
Management of Complex Root Fractures in Young Patients—Case Series and a Literature Review
Journal of Clinical Medicine,
Journal Year:
2024,
Volume and Issue:
13(22), P. 6753 - 6753
Published: Nov. 10, 2024
Root
fractures
are
defined
as
injuries
involving
dentine,
cementum,
and
the
pulp.
They
rare,
they
account
for
0.5-7%
of
dental
in
permanent
teeth.
may
be
result
direct
trauma
to
teeth
or
indirect
oral
cavity.
Their
incidence
is
highest
group
adolescent
patients
aged
11
20
years.
The
purpose
paper
review
literature
supported
by
a
case
series
with
three
different
types
root
various
healing
patterns,
though
all
successful
long-term
treatment
outcomes.
Language: Английский
The Diagnosis and Management of Infraoccluded Deciduous Molars: A Systematic Review
Children,
Journal Year:
2024,
Volume and Issue:
11(11), P. 1375 - 1375
Published: Nov. 12, 2024
The
infraocclusion
(IO)
of
primary
molars,
often
seen
in
retained
deciduous
teeth,
is
a
common
condition
that
presents
significant
challenges
for
pediatric
oral
health.
It
occurs
when
molars
are
positioned
below
the
occlusal
plane
due
to
absence
permanent
successors,
leading
complications
such
as
misaligned
impaired
chewing,
and
long-term
dental
health
issues.
Objectives:
This
study
examines
IO
prevalence,
diagnosis,
treatment
approaches.
Methods:
A
systematic
review
following
PRISMA
guidelines
was
conducted,
searching
PubMed,
Web
Science,
Scopus
articles
from
last
15
years.
Nine
were
included
qualitative
analysis.
Results:
associated
with
several
complications,
including
root
resorption,
altered
eruption
adjacent
space
loss
within
arch.
Clinical
radiographic
evaluations
key
early
detection.
Severe
cases
require
invasive
treatments,
tooth
extraction
maintenance,
while
mild
could
be
monitored.
Conclusions:
prevalent
dentistry
can
lead
issues
if
untreated.
Early
detection
intervention
crucial
preventing
like
misalignment
impacted
premolars.
Tailored
strategies
based
on
severity,
along
increased
awareness
among
practitioners,
essential
improve
outcomes
affected
children.
Language: Английский