Clinical Neurology and Neurosurgery, Journal Year: 2024, Volume and Issue: 246, P. 108587 - 108587
Published: Oct. 11, 2024
Language: Английский
The Journal of Headache and Pain, Journal Year: 2025, Volume and Issue: 26(1)
Published: Feb. 20, 2025
Migraine is a chronic neurological condition that has well-documented, yet not fully understood connection to stroke, particularly in patients who experience migraine with aura (MA). Although can rarely be directly related the form of migrainous infarction, it serves as an independent risk factor, when combined other factors such smoking or hypertension. This study will thoroughly review and summarize existing literature regarding relationship between stroke. Several key processes are common both stroke migraine. These include cortical spreading depression, MA, endothelial dysfunction, which activates local inflammatory responses, vasculopathy, often appears white matter hyperintensities on neuroimaging. Furthermore, microRNAs also play significant role pathogenesis by targeting genes CALCA, regulates calcitonin gene-related peptide, factor involved pathophysiology conditions. There several genetic links including monogenic diseases loci. Moreover, various conditions linked patent foramen ovale (PFO), atrial fibrillation, carotid artery dissection, platelet dyslipidemia, obesity, hyperhomocysteinemia, elevated estrogen levels, hormonal contraceptives. Notably, PFO found have experienced cryptogenic well those MA. While microemboli associated may provoke ischemic events attacks, effectiveness closure alleviating symptoms produced varying results. worse outcomes after larger volumes poorer functional outcomes, while migraines hemorrhagic less understood. serve mimic (condition presenting similar stroke) chameleon (unrecognized misdiagnosed migraine), leading diagnostic treatment errors. The interplay complex, involving shared overlapping factors. cause for precise mechanisms remain unclear, warranting further research clarify their enhance clinical management.
Language: Английский
Citations
1
Cureus, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 30, 2025
This article aims to present and discuss a case of patient presented with stroke-like symptoms that fluctuated rapid initial improvement followed by recurrence slow resolution over period six days. A 57-year-old male past medical history chronic myeloid leukemia (CML), unspecified seizure disorder, hyperlipidemia (HLD), hypertension (HTN), peptic ulcer disease (PUD), type II diabetes mellitus (T2DM) right-sided focal neurological deficits (FNDs). The initially called the ambulance for intractable abdominal pain five-day melena one episode hematemesis ground-level fall, during which he was witnessed family shaking unresponsive. He alert oriented when developed FNDs en route hospital. differential included stroke, transient ischemic attack (TIA), Todd's paralysis (TP), hemiplegic migraine (HM). clinical picture complex; patient's T2DM, HLD, HTN all placed him at high risk stroke suggested TP. Computed tomography (CT) magnetic resonance imaging (MRI) were crucial in eliminating as possible etiology, TIA ruled out persisted. Imaging, findings, investigation history, critical reasoning helped rule finally diagnosed treated sporadic HM unexpected fluctuations aura. fluctuation symptom intensity raises questions about pathophysiology migrainous aura, how it produces FNDs, can explain presentation this patient.
Language: Английский
Citations
0
The Analyst, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
This work designed an electrochemical immunoassay for interleukin-6 on functionalized glassy carbon electrode using Prussian blue-doped CaCO 3 nanoparticle-labeled secondary antibodies.
Language: Английский
Citations
1
Clinical Neurology and Neurosurgery, Journal Year: 2024, Volume and Issue: 246, P. 108587 - 108587
Published: Oct. 11, 2024
Language: Английский
Citations
0