Goal-oriented therapy of coagulopathy in liver transplantation in children (literature review) DOI Creative Commons
D. I. Novikov,

A. Yu. Zaitsev,

А. В. Филин

et al.

Messenger of Anesthesiology and Resuscitation, Journal Year: 2025, Volume and Issue: 22(2), P. 127 - 138

Published: April 16, 2025

Introduction. Methods for correcting perioperative blood loss and hemostasis disorders in children during liver transplantation are still controversial largely conducted empirically by specialists. Additional difficulties imposed the features of a continuously growing developing organism, as well following system. The objective was to analyze modern approaches correction period transplantation. Materials methods . analysis literary sources indexed from 2000 2024 databases PubMed, Google Scholar, Cochrane MEDLINE E-Library (for Russian authors). Results. literature has shown that at present, children, personalized approach prevails choosing tactics infusion – transfusion therapy changes Modern aimed fastest possible identification specific pro- anticoagulant factors directly «at patient’s bedside» targeted each element. Conclusion Despite active development improvement transplantation, improving pharmacotherapy protocols, minimizing time obtain laboratory data reducing influence human factor on interpretation results treatment choice, study system its is very far final stage.

Language: Английский

Goal-oriented therapy of coagulopathy in liver transplantation in children (literature review) DOI Creative Commons
D. I. Novikov,

A. Yu. Zaitsev,

А. В. Филин

et al.

Messenger of Anesthesiology and Resuscitation, Journal Year: 2025, Volume and Issue: 22(2), P. 127 - 138

Published: April 16, 2025

Introduction. Methods for correcting perioperative blood loss and hemostasis disorders in children during liver transplantation are still controversial largely conducted empirically by specialists. Additional difficulties imposed the features of a continuously growing developing organism, as well following system. The objective was to analyze modern approaches correction period transplantation. Materials methods . analysis literary sources indexed from 2000 2024 databases PubMed, Google Scholar, Cochrane MEDLINE E-Library (for Russian authors). Results. literature has shown that at present, children, personalized approach prevails choosing tactics infusion – transfusion therapy changes Modern aimed fastest possible identification specific pro- anticoagulant factors directly «at patient’s bedside» targeted each element. Conclusion Despite active development improvement transplantation, improving pharmacotherapy protocols, minimizing time obtain laboratory data reducing influence human factor on interpretation results treatment choice, study system its is very far final stage.

Language: Английский

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