
Diabetology & Metabolic Syndrome, Journal Year: 2024, Volume and Issue: 16(1)
Published: Dec. 18, 2024
Recently, International Diabetes Federation position statement has adopted one-hour post-load glucose (1hPG) ≥ 8.6 mmol/L for diagnosing intermediate hyperglycemia. We aimed to assess the association of 1hPG with metabolic syndrome (MetS) and its components, as well interaction between sex on MetS components in Chinese people at high risk diabetes. The cross-sectional study was conducted DaQing city HeiLongJiang Province, China August, 2023 January, 2024. Eligible individuals fasting 5.6–6.9 age 25–55 years health checkup data year or least one factor diabetes were invited receive oral tolerance test biochemical examinations. Individuals self-reported presence usage glucose-lowering medication excluded. defined three five according Society criteria. Logistic regression performed evaluate components. Additive estimated using relative excess due interaction, attributable proportion (AP), synergy index. A total 2419 subjects comprising 1465 men (60.6%) a mean 45.77 ± 6.20 included, prevalence 46.8%, 59.7% 27.1% women. associated (aOR = 4.40, 95% CI 3.26–6.01), elevated blood pressure 1.46, 1.13–1.89), hyperglycemia 15.46, 11.56–20.98), reduced HDL-C 1.51, 1.07–2.15) overall population, whereas no significant 1.36, 0.97–1.91) dyslipidemia women (elevated TG: aOR 0.81, 0.47–1.39; HDL-C: 1.08, 0.49–2.37). effect observed, 31% attributed (AP 0.31, 0.06–0.49). There an additive among sex-specific strategies should be taken into consideration cardiometabolic disorder identification management.
Language: Английский